Design Automation Methods And Tools For Microfluidics Based Biochips


Design Automation Methods And Tools For Microfluidics Based Biochips
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Design Automation Methods And Tools For Microfluidics Based Biochips


Design Automation Methods And Tools For Microfluidics Based Biochips
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Author : Jun Zeng
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-11-08

Design Automation Methods And Tools For Microfluidics Based Biochips written by Jun Zeng and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-08 with Technology & Engineering categories.


Design Automation Methods and Tools for Microfluidics-Based Biochips deals with all aspects of design automation for microfluidics-based biochips. Experts have contributed chapters on many aspects of biochip design automation. Topics covered include: device modeling; adaptation of bioassays for on-chip implementations; numerical methods and simulation tools; architectural synthesis, scheduling and binding of assay operations; physical design and module placement; fault modeling and testing; and reconfiguration methods.



Digital Microfluidic Biochips


Digital Microfluidic Biochips
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Author : Krishnendu Chakrabarty
language : en
Publisher: CRC Press
Release Date : 2010-05-03

Digital Microfluidic Biochips written by Krishnendu Chakrabarty and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-03 with Medical categories.


Microfluidics-based biochips combine electronics with biochemistry, providing access to new application areas in a wide variety of fields. Continued technological innovations are essential to assuring the future role of these chips in functional diversification in biotech, pharmaceuticals, and other industries.Revolutionary guidance on design, opti



Design And Testing Of Digital Microfluidic Biochips


Design And Testing Of Digital Microfluidic Biochips
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Author : Yang Zhao
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-25

Design And Testing Of Digital Microfluidic Biochips written by Yang Zhao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-25 with Technology & Engineering categories.


This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point.



Micro Electrode Dot Array Digital Microfluidic Biochips


Micro Electrode Dot Array Digital Microfluidic Biochips
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Author : Zipeng Li
language : en
Publisher: Springer
Release Date : 2018-12-14

Micro Electrode Dot Array Digital Microfluidic Biochips written by Zipeng Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-14 with Technology & Engineering categories.


This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.



Digital Microfluidic Biochips


Digital Microfluidic Biochips
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Author : Krishnendu Chakrabarty
language : en
Publisher: CRC Press
Release Date : 2018-10-03

Digital Microfluidic Biochips written by Krishnendu Chakrabarty and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-03 with Technology & Engineering categories.


Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.



Hardware Software Co Design And Optimization For Cyberphysical Integration In Digital Microfluidic Biochips


Hardware Software Co Design And Optimization For Cyberphysical Integration In Digital Microfluidic Biochips
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Author : Yan Luo
language : en
Publisher: Springer
Release Date : 2014-08-06

Hardware Software Co Design And Optimization For Cyberphysical Integration In Digital Microfluidic Biochips written by Yan Luo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-06 with Technology & Engineering categories.


This book describes a comprehensive framework for hardware/software co-design, optimization, and use of robust, low-cost, and cyberphysical digital microfluidic systems. Readers with a background in electronic design automation will find this book to be a valuable reference for leveraging conventional VLSI CAD techniques for emerging technologies, e.g., biochips or bioMEMS. Readers from the circuit/system design community will benefit from methods presented to extend design and testing techniques from microelectronics to mixed-technology microsystems. For readers from the microfluidics domain, this book presents a new design and development strategy for cyberphysical microfluidics-based biochips suitable for large-scale bioassay applications. • Takes a transformative, “cyberphysical” approach towards achieving closed-loop and sensor feedback-driven biochip operation under program control; • Presents a “physically-aware” system reconfiguration technique that uses sensor data at intermediate checkpoints to dynamically reconfigure biochips; • Enables readers to simplify the structure of biochips, while facilitating the “general-purpose” use of digital microfluidic biochips for a wider range of applications.



Computer Aided Design Of Microfluidic Very Large Scale Integration Mvlsi Biochips


Computer Aided Design Of Microfluidic Very Large Scale Integration Mvlsi Biochips
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Author : Kai Hu
language : en
Publisher: Springer
Release Date : 2017-04-05

Computer Aided Design Of Microfluidic Very Large Scale Integration Mvlsi Biochips written by Kai Hu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-05 with Technology & Engineering categories.


This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques.



Secure And Trustworthy Cyberphysical Microfluidic Biochips


Secure And Trustworthy Cyberphysical Microfluidic Biochips
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Author : Jack Tang
language : en
Publisher: Springer
Release Date : 2019-05-28

Secure And Trustworthy Cyberphysical Microfluidic Biochips written by Jack Tang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-28 with Technology & Engineering categories.


This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.



Fault Tolerant Digital Microfluidic Biochips


Fault Tolerant Digital Microfluidic Biochips
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Author : Paul Pop
language : en
Publisher: Springer
Release Date : 2015-09-07

Fault Tolerant Digital Microfluidic Biochips written by Paul Pop and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-07 with Technology & Engineering categories.


This book describes for researchers in the fields of compiler technology, design and test, and electronic design automation the new area of digital microfluidic biochips (DMBs), and thus offers a new application area for their methods. The authors present a routing-based model of operation execution, along with several associated compilation approaches, which progressively relax the assumption that operations execute inside fixed rectangular modules. Since operations can experience transient faults during the execution of a bioassay, the authors show how to use both offline (design time) and online (runtime) recovery strategies. The book also presents methods for the synthesis of fault-tolerant application-specific DMB architectures. · Presents the current models used for the research on compilation and synthesis techniques of DMBs in a tutorial fashion; · Includes a set of “benchmarks”, which are presented in great detail and includes the source code of most of the techniques presented, including solutions to the basic compilation and synthesis problems; · Discusses several new research problems in detail, using numerous examples.



Design Automation Of Continuous Flow Based Microuidic Biochips


Design Automation Of Continuous Flow Based Microuidic Biochips
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Author : Jeffrey Michael McDaniel
language : en
Publisher:
Release Date : 2016

Design Automation Of Continuous Flow Based Microuidic Biochips written by Jeffrey Michael McDaniel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Biochips categories.


Continuous flow-based microfluidic biochips use actively controlled valves to manipulate the flow of fluids through components and channels to automate biochemical protocols. The current state-of-the-art design practices require biochemists with no engineering experience to manually design these devices. This process severely limits the realistic complexity a device can have, limiting the applications they can be used for. These devices can be viewed as a netlist of components and their interconnections, along with a protocol to be performed, similar to a how an integrated circuit can be abstracted. This thesis introduces an end to end tool-chain capable of taking a high level biochemical protocol and automatically generating a device design that can be fabricated to perform that experiment. This is done through the use of design automation algorithms adapted from the electronic design automation (EDA) industry