Diabetes And Heart Failure Pathogenesis And Novel Therapeutic Approaches
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Diabetes And Heart Failure Pathogenesis And Novel Therapeutic Approaches
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Author : Celestino Sardu
language : en
Publisher: Frontiers Media SA
Release Date : 2019-05-15
Diabetes And Heart Failure Pathogenesis And Novel Therapeutic Approaches written by Celestino Sardu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-15 with categories.
Diabetic Cardiomyopathy
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Author : Belma Turan
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-08
Diabetic Cardiomyopathy written by Belma Turan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-08 with Science categories.
Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.
Diabetes And Cardiovascular Disease
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Author : Michael T. Johnstone
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-05-25
Diabetes And Cardiovascular Disease written by Michael T. Johnstone and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-25 with Health & Fitness categories.
This extensively updated and expanded second edition reflects new research, advances in clinical care, and the growing recognition that diabetes mellitus is a risk factor for cardiovascular disease. Written for the practicing clinician as a comprehensive review of diabetic vascular disease, the book both explains the basic pathophysiology of the disease and details the latest diagnostic and therapeutic approaches. The authors have added new chapters on percutaneous interventional therapy in cardiac and peripheral vascular disease, cardiovascular surgery in diabetes, therapeutic interventions to improve endothelial function in diabetes, PARP activation and nitrosative stress in the development of the cardiovascular system, and PPARs and their emerging role in vascular biology, inflammation, and atherosclerosis.
Acute Heart Failure
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Author : Alexandre Mebazaa
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-24
Acute Heart Failure written by Alexandre Mebazaa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-24 with Medical categories.
For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
Novel Therapeutic Approaches Targeting Oxidative Stress
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Author : Pawan Kumar Maurya
language : en
Publisher: Academic Press
Release Date : 2022-02-18
Novel Therapeutic Approaches Targeting Oxidative Stress written by Pawan Kumar Maurya and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-18 with Science categories.
Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives. Explores oxidative stress in a variety of diseases, including neurological disorders, cardiovascular diseases, age-related diseases, and cancer Covers a range of therapeutic approaches to target oxidative stress Includes chapters on the application of novel drug delivery systems and diagnostic biosensors to oxidative stress Features case studies illustrating the targeting of oxidative stress
International Textbook Of Diabetes Mellitus
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Author : R. A. DeFronzo
language : en
Publisher: John Wiley & Sons
Release Date : 2015-03-11
International Textbook Of Diabetes Mellitus written by R. A. DeFronzo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-11 with Medical categories.
The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.
Therapeutic Strategies For Heart Failure
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Author : Naoki Sato
language : en
Publisher: Springer
Release Date : 2018-01-24
Therapeutic Strategies For Heart Failure written by Naoki Sato and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-24 with Medical categories.
This book introduces pathophysiology and practical heart failure (HF) management at the acute, in-hospital stages during hospitalization and also in the end-stages of HF. Given its increasing incidence and prevalence, we live in a world that is essentially facing an HF pandemic. A country with an ageing population, Japan is unique in terms of the selection of medical treatment, diagnostic techniques, team managing and other approaches. This book sheds new light on the clinical challenges involved in reducing re-hospitalization and improving patients’ prognosis and ADL/QOL, while also reporting on the status quo in Japan. By highlighting these challenges and the methods used to address them, it will encourage experts around the globe to intensively discuss and accelerate research in this field. Including contributions by authors who have played central roles in managing HF in Japan, the book offers an indispensable guide not only for clinicians, technicians and nurses in this field, but also for general physicians, emergency physicians and all others who are involved in the management of acute and end-stage HF.
Diabetes Mellitus In Children
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Author : Mark A. Sperling
language : en
Publisher:
Release Date : 2005
Diabetes Mellitus In Children written by Mark A. Sperling and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Children categories.
Depression And Diabetes
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Author : Wayne Katon
language : en
Publisher: John Wiley & Sons
Release Date : 2011-06-09
Depression And Diabetes written by Wayne Katon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-09 with Medical categories.
In recent years, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. The WPA is providing an update of currently available evidence on these interrelationships by the publication of three books, dealing with the comorbidity of depression with diabetes, heart disease and cancer. Depression is a frequent and serious comorbid condition in diabetes, which adversely affects quality of life and the long-term prognosis. Co-occurrent depression presents peculiar clinical challenges, making both conditions harder to manage. Depression and Diabetes is the first book devoted to the interaction between these common disorders. World leaders in diabetes, depression and public health synthesize current evidence, including some previously unpublished data, in a concise, easy-to-read format. They provide an overview of the epidemiology, pathogenesis, medical costs, management, and public health and cultural implications of the comorbidity between depression and diabetes. The book describes how the negative consequences of depression in diabetes could be avoided, given that effective depression treatments for diabetic patients are available. Its practical approach makes the book ideal for all those involved in the management of these patients: psychiatrists, psychologists, diabetologists, general practitioners, diabetes specialist nurses and mental health nurses.
The Breathless Heart
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Author : Michele Emdin
language : en
Publisher: Springer
Release Date : 2016-11-25
The Breathless Heart written by Michele Emdin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-25 with Medical categories.
This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present historical background information on Cheyne-Stokes respiration (CSR), clarify terminology, and explain the mechanics and chemistry of respiration. Following a description of the physiology of respiration, the pathophysiology underlying central apneas in different disorders and particularly in heart failure is discussed. The similarities and differences of obstructive and central apneas are then considered. The book looks beyond the concept of sleep apnea to daytime CSR and periodic breathing during effort and contrasts the opposing views of CSR as a compensatory phenomenon or as detrimental to the failing heart. The diagnostic tools currently in use for the detection of CSR are thoroughly reviewed, with guidance on interpretation of findings. The book concludes by describing the various forms of treatment that are available for CSR and by explaining how to select patients for treatment.