Home eBooks Download › discovering biomolecular mechanisms with computational biology

Discovering Biomolecular Mechanisms With Computational Biology

Download Discovering Biomolecular Mechanisms With Computational Biology PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Discovering Biomolecular Mechanisms With Computational Biology book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Discovering Biomolecular Mechanisms With Computational Biology

DOWNLOAD
Author : Frank Eisenhaber
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-20

Discovering Biomolecular Mechanisms With Computational Biology written by Frank Eisenhaber and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-20 with Science categories.

This anthology presents critical reviews of methods and high-impact applications in computational biology that lead to results that non-bioinformaticians must also know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology explores the methodology of translating sequence strings into biological knowledge and considers exemplary groundbreaking results such as unexpected enzyme discoveries. This book also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation.

Discovering Biomolecular Mechanisms With Computational Biology

DOWNLOAD
Author : Frank Eisenhaber
language : en
Publisher: Springer
Release Date : 2006-06-13

Discovering Biomolecular Mechanisms With Computational Biology written by Frank Eisenhaber and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-13 with Medical categories.

Bioinformatics For Systems Biology

DOWNLOAD
Author : Stephen Krawetz
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-11

Bioinformatics For Systems Biology written by Stephen Krawetz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-11 with Science categories.

Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.

Mechanism And Causality In Biology And Economics

DOWNLOAD
Author : Hsiang-Ke Chao
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-31

Mechanism And Causality In Biology And Economics written by Hsiang-Ke Chao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-31 with Philosophy categories.

This volume addresses fundamental issues in the philosophy of science in the context of two most intriguing fields: biology and economics. Written by authorities and experts in the philosophy of biology and economics, Mechanism and Causality in Biology and Economics provides a structured study of the concepts of mechanism and causality in these disciplines and draws careful juxtapositions between philosophical apparatus and scientific practice. By exploring the issues that are most salient to the contemporary philosophies of biology and economics and by presenting comparative analyses, the book serves as a platform not only for gaining mutual understanding between scientists and philosophers of the life sciences and those of the social sciences, but also for sharing interdisciplinary research that combines both philosophical concepts in both fields. The book begins by defining the concepts of mechanism and causality in biology and economics, respectively. The second and third parts investigate philosophical perspectives of various causal and mechanistic issues in scientific practice in the two fields. These two sections include chapters on causal issues in the theory of evolution; experiments and scientific discovery; representation of causal relations and mechanism by models in economics. The concluding section presents interdisciplinary studies of various topics concerning extrapolation of life sciences and social sciences, including chapters on the philosophical investigation of conjoining biological and economic analyses with, respectively, demography, medicine and sociology.

Immunological Bioinformatics

DOWNLOAD
Author : Ole Lund
language : en
Publisher: MIT Press
Release Date : 2005-06-17

Immunological Bioinformatics written by Ole Lund and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-17 with Computers categories.

Using bioinformatics methods to generate a systems-level view of the immune system; description of the main biological concepts and the new data-driven algorithms. Despite the fact that advanced bioinformatics methodologies have not been used as extensively in immunology as in other subdisciplines within biology, research in immunological bioinformatics has already developed models of components of the immune system that can be combined and that may help develop therapies, vaccines, and diagnostic tools for such diseases as AIDS, malaria, and cancer. In a broader perspective, specialized bioinformatics methods in immunology make possible for the first time a systems-level understanding of the immune system. The traditional approaches to immunology are reductionist, avoiding complexity but providing detailed knowledge of a single event, cell, or molecular entity. Today, a variety of experimental bioinformatics techniques connected to the sequencing of the human genome provides a sound scientific basis for a comprehensive description of the complex immunological processes. This book offers a description of bioinformatics techniques as they are applied to immunology, including a succinct account of the main biological concepts for students and researchers with backgrounds in mathematics, statistics, and computer science as well as explanations of the new data-driven algorithms in the context of biological data that will be useful for immunologists, biologists, and biochemists working on vaccine design. In each chapter the authors show interesting biological insights gained from the bioinformatics approach. The book concludes by explaining how all the methods presented in the book can be integrated to identify immunogenic regions in microorganisms and host genomes.

Genesis In The Beginning

DOWNLOAD
Author : Joseph Seckbach
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-19

Genesis In The Beginning written by Joseph Seckbach and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-19 with Science categories.

Genesis – In The Beginning deals with the origin and diversity of Life and early biological evolution and discusses the question of where (hot or cold sources) and when the beginning of Life took place. Among the sections are chapters dealing with prebiotic chemical processes and considering self-replication of polymers in mineral habitats. One chapter is dedicated to the photobiological regime on early Earth and the emergence of Life. This volume covers the role of symmetry, information and order (homochrial biomolecules) in the beginning of Life. The models of protocells and the genetic code with gene transfer are important topics in this volume. Three chapters discuss the Panspermia hypothesis (to answer “Are we from outer Space?”). Other chapters cover the Astrobiological aspects of Life in the Universe in extraterrestrial Planets of the Solar System and deal with cometary hydrosphere (and its connection to Earth). We conclude with the history and frontiers of Astrobiogy.

Computational Systems Biology Of Pathogen Host Interactions

DOWNLOAD
Author : Saliha Durmuş
language : en
Publisher: Frontiers Media SA
Release Date : 2016-05-30

Computational Systems Biology Of Pathogen Host Interactions written by Saliha Durmuş and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-30 with Microbiology categories.

A thorough understanding of pathogenic microorganisms and their interactions with host organisms is crucial to prevent infectious threats due to the fact that Pathogen-Host Interactions (PHIs) have critical roles in initiating and sustaining infections. Therefore, the analysis of infection mechanisms through PHIs is indispensable to identify diagnostic biomarkers and next-generation drug targets and then to develop strategic novel solutions against drug-resistance and for personalized therapy. Traditional approaches are limited in capturing mechanisms of infection since they investigate hosts or pathogens individually. On the other hand, the systems biology approach focuses on the whole PHI system, and is more promising in capturing infection mechanisms. Here, we bring together studies on the below listed sections to present the current picture of the research on Computational Systems Biology of Pathogen-Host Interactions: - Computational Inference of PHI Networks using Omics Data - Computational Prediction of PHIs - Text Mining of PHI Data from the Literature - Mathematical Modeling and Bioinformatic Analysis of PHIs Computational Inference of PHI Networks using Omics Data Gene regulatory, metabolic and protein-protein networks of PHI systems are crucial for a thorough understanding of infection mechanisms. Great advances in molecular biology and biotechnology have allowed the production of related omics data experimentally. Many computational methods are emerging to infer molecular interaction networks of PHI systems from the corresponding omics data. Computational Prediction of PHIs Due to the lack of experimentally-found PHI data, many computational methods have been developed for the prediction of pathogen-host protein-protein interactions. Despite being emerging, currently available experimental PHI data are far from complete for a systems view of infection mechanisms through PHIs. Therefore, computational methods are the main tools to predict new PHIs. To this end, the development of new computational methods is of great interest. Text Mining of PHI Data from Literature Despite the recent development of many PHI-specific databases, most data relevant to PHIs are still buried in the biomedical literature, which demands for the use of text mining techniques to unravel PHIs hidden in the literature. Only some rare efforts have been performed to achieve this aim. Therefore, the development of novel text mining methods specific for PHI data retrieval is of key importance for efficient use of the available literature. Mathematical Modeling and Bioinformatic Analysis of PHIs After the reconstruction of PHI networks experimentally and/or computationally, their mathematical modeling and detailed computational analysis is required using bioinformatics tools to get insights on infection mechanisms. Bioinformatics methods are increasingly applied to analyze the increasing amount of experimentally-found and computationally-predicted PHI data.

Omics In Clinical Practice

DOWNLOAD
Author : Yu Liu
language : en
Publisher: CRC Press
Release Date : 2014-06-20

Omics In Clinical Practice written by Yu Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-20 with Science categories.

This book serves as an introduction to genomics, proteomics, and transcriptomics, putting these fields in relation to human disease and ailments. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation to genomics, proteomics, and transcriptomics. The topic of companion diagnostics is also covered. The book is broken into five sections. Part I examines the connection between omics and human disease. Part II looks at the applications for the fields of translational and personalized medicine. Part III focuses on molecular and genetic markers. Part IV describes the use of omics while studying pathogens, and Part V examines the applications for companion diagnostics. The book: • Introduces genomics, proteomics, and transcriptomics in relation to human disease and ailments • Considers the role of translation and personalized medicine in relation to genomics, proteomics, and transcriptomics • Covers molecular and genetic markers • Considers the role of genomics, proteomics, and transcriptomics in relation to pathogen detection, evolution, and infection • Covers companion diagnostics in relation to genomics, proteomics, and transcriptomics clinical applications and research

Information Processing And Living Systems

DOWNLOAD
Author : Vladimir B. Baji?
language : en
Publisher: World Scientific
Release Date : 2005

Information Processing And Living Systems written by Vladimir B. Baji? and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.

Information processing and information flow occur in the course of an organism's development and throughout its lifespan. Organisms do not exist in isolation, but interact with each other constantly within a complex ecosystem. The relationships between organisms, such as those between prey or predator, host and parasite, and between mating partners, are complex and multidimensional. In all cases, there is constant communication and information flow at many levels.This book focuses on information processing by life forms and the use of information technology in understanding them. Readers are first given a comprehensive overview of biocomputing before navigating the complex terrain of natural processing of biological information using physiological and analogous computing models. The remainder of the book deals with ?artificial? processing of biological information as a human endeavor in order to derive new knowledge and gain insight into life forms and their functioning. Specific innovative applications and tools for biological discovery are provided as the link and complement to biocomputing.Since ?artificial? processing of biological information is complementary to natural processing, a better understanding of the former helps us improve the latter. Consequently, readers are exposed to both domains and, when dealing with biological problems of their interest, will be better equipped to grasp relevant ideas.

The Evolution Of Biomineralization In Metazoans

DOWNLOAD
Author : Sylvain Marcellini
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-01

The Evolution Of Biomineralization In Metazoans written by Sylvain Marcellini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-01 with Science categories.

Discovering Biomolecular Mechanisms With Computational Biology

Recent Posts