Immunological Bioinformatics
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Immunological Bioinformatics
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Author : Ole Lund
language : en
Publisher: MIT Press
Release Date : 2024-02-06
Immunological Bioinformatics written by Ole Lund and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-06 with Computers categories.
Using bioinformatics methods to generate a systems-level view of the immune system; description of the main biological concepts and the new data-driven algorithms. Despite the fact that advanced bioinformatics methodologies have not been used as extensively in immunology as in other subdisciplines within biology, research in immunological bioinformatics has already developed models of components of the immune system that can be combined and that may help develop therapies, vaccines, and diagnostic tools for such diseases as AIDS, malaria, and cancer. In a broader perspective, specialized bioinformatics methods in immunology make possible for the first time a systems-level understanding of the immune system. The traditional approaches to immunology are reductionist, avoiding complexity but providing detailed knowledge of a single event, cell, or molecular entity. Today, a variety of experimental bioinformatics techniques connected to the sequencing of the human genome provides a sound scientific basis for a comprehensive description of the complex immunological processes. This book offers a description of bioinformatics techniques as they are applied to immunology, including a succinct account of the main biological concepts for students and researchers with backgrounds in mathematics, statistics, and computer science as well as explanations of the new data-driven algorithms in the context of biological data that will be useful for immunologists, biologists, and biochemists working on vaccine design. In each chapter the authors show interesting biological insights gained from the bioinformatics approach. The book concludes by explaining how all the methods presented in the book can be integrated to identify immunogenic regions in microorganisms and host genomes.
Conceptual Modelling In Computational Immunology
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Author : Martina Husáková
language : en
Publisher: Tomáš Bruckner
Release Date : 2015-09-10
Conceptual Modelling In Computational Immunology written by Martina Husáková and has been published by Tomáš Bruckner this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-10 with Computers categories.
Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.
Ai Assisted Computational Approaches For Immunological Disorders
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Author : Chen, Jen-Tsung
language : en
Publisher: IGI Global
Release Date : 2025-05-13
Ai Assisted Computational Approaches For Immunological Disorders written by Chen, Jen-Tsung and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-13 with Medical categories.
Based on accelerated computing and advanced algorithms, artificial intelligence (AI) has become a game-changer in diverse fields. In biomedical science, AI models based on machine learning, deep learning, and generative AI, together with upgraded computational and systems biology, provide smart, precise, and personalized medicine and healthcare. In the field of clinical immunology, which deals with intrinsic complicated immune systems for combating immunological disorders, AI technologies have the potential to solve problems based on identification, prediction, simulation, and modeling. AI algorithms may impact sustainable clinical healthcare and future immunology diagnoses. AI-Assisted Computational Approaches for Immunological Disorders explores precision clinical medicine and personalized healthcare in major immunological disorders, such as immunodeficiency, autoimmune diseases, allergies, asthma, cancers, and neurological diseases. It analyzes clinical healthcare big data, genomics, and high-throughput multiple omics based on single-cell and high-dimensional data for their technical advances, clinical applications, challenges, and future directions. Covering topics such as cell therapy, reducing complications, and drug development, this book is an excellent resource for immunologists, biologists, healthcare practitioners, professionals, researchers, scholars, academicians, and more.
Immunological Bioinformatics
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Author :
language : en
Publisher:
Release Date : 2005
Immunological Bioinformatics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Bioinformatics categories.
Methods And Applications Of Computational Immunology
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Author : Victor Greiff
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-30
Methods And Applications Of Computational Immunology written by Victor Greiff and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with categories.
Bioinformatics For Immunomics
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Author : Darren D.R. Flower
language : en
Publisher: Springer
Release Date : 2009-10-03
Bioinformatics For Immunomics written by Darren D.R. Flower and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.
Like many words, the term “immunomics” equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism – be that virus, bacteria, fungus, or parasite – or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.
Immunology
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Author : Anil Sharma
language : en
Publisher: CRC Press
Release Date : 2019-03-07
Immunology written by Anil Sharma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-07 with Health & Fitness categories.
Immunology has emerged as a key component of the curricula of graduate and postgraduate courses in biotechnology, microbiology, biochemistry, bioinformatics, and other interdisciplinary fields of biology, including zoology, veterinary science, and medicine. As a basic introductory textbook on one of the fastest-moving and most challenging areas of immunological science, this book contains the most recent information about immunologic mechanisms and their importance, along with various molecular techniques employed in immunology. The short and concise text helps make the structures, processes, and interactions of the immune system easily comprehensible. The book includes chapters on immunoinformatics as well as the immune system of the brain, rarely found in any of the immunology books published so far. Many diverse and interesting aspects of the advances in immunology have also been covered, including tumor immunology and immunodeficiency disorders. The easy-to-understand concepts presented in the textbook make it an ideal companion for learners preparing for competitive and other examinations. Undergraduate, postgraduate, and PhD students, people from the industry and academia, and research scholars will immensely benefit from it.
Systems Immunology And Infection Microbiology
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Author : Bor-Sen Chen
language : en
Publisher: Academic Press
Release Date : 2021-03-16
Systems Immunology And Infection Microbiology written by Bor-Sen Chen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-16 with Science categories.
Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate development procedures and help users understand the results of systems immunology and infection microbiology. Chapters discuss systems immunology, systems infection microbiology, systematic inflammation and immune responses in restoration and regeneration process, systems' innate and adaptive immunity in infection process, systematic genetic and epigenetic pathogenic/defensive mechanism during bacterial infection on human cells is introduced, and the systematic genetic and epigenetic pathogenic/defensive mechanisms during viral infection on human cells. This book provides new big data-driven and systems-driven systems immunology and infection microbiology to researchers applying systems biology and bioinformatics in their work. It is also invaluable to several members of biomedical field who are interested in learning more about those approaches. - Encompasses one applicable example in every chapter to illustrate the solution procedure from big data mining, network modeling, host/pathogen cross-talk detection, drug target identification and systems drug design - Presents flowcharts to represent the development procedure of systematic immunology and infection in a very clear format - Contains 100 color diagrams to help readers understand the related biological networks, their corresponding mechanisms, and significant network biomarkers for therapeutic drug design
Immunological Bioinformatics
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Author :
language : en
Publisher:
Release Date : 2005
Immunological Bioinformatics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Bioinformatics categories.
Vaccinology
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Author : W. John W. Morrow
language : en
Publisher: John Wiley & Sons
Release Date : 2012-06-12
Vaccinology written by W. John W. Morrow and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-12 with Medical categories.
Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.