Discovery And Development Of Neuroprotective Agents From Natural Products
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Discovery And Development Of Neuroprotective Agents From Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2017-05-18
Discovery And Development Of Neuroprotective Agents From Natural Products written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-18 with Science categories.
Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer's disease, Parkinson's disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. - Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases - Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
Discovery And Development Of Therapeutics From Natural Products Against Neglected Tropical Diseases
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2019-04-15
Discovery And Development Of Therapeutics From Natural Products Against Neglected Tropical Diseases written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Science categories.
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Bioactive Natural Products Opportunities And Challenges In Medicinal Chemistry
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Author : Goutam Brahmachari
language : en
Publisher: World Scientific
Release Date : 2011-10-17
Bioactive Natural Products Opportunities And Challenges In Medicinal Chemistry written by Goutam Brahmachari and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-17 with Science categories.
Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.
Neuroprotective Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-01
Neuroprotective Natural Products written by Goutam Brahmachari and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-01 with Medical categories.
Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine. With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.
Cardioprotective Natural Products Promises And Hopes
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Author : Goutam Brahmachari
language : en
Publisher: World Scientific
Release Date : 2017-10-27
Cardioprotective Natural Products Promises And Hopes written by Goutam Brahmachari and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-27 with Medical categories.
Cardioprotective Natural Products: Promises and Hopes focuses on the recent advances in the research of bioactive natural products with cardioprotective potential against various cardiovascular diseases/disorders. The aim of this book is to underline the promise and future hope in bioactive natural molecules, herbal formulations, natural dietary supplements and related materials in the prevention and cure of cardiovascular diseases in a scientific way.This book, which comprises a variety of about 9 chapters written by active researchers and leading experts, brings together an overview of current discoveries and trends in this field. This volume is also an outstanding source of information with regard to the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach adopted in this book ensures that it is much more interesting to scientists deeply engaged in the research and/or use of bioactive natural products. It will serve not only as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to prevent and treat disease manifestations, but will hopefully also motivate young scientists to engage in the dynamic field of natural products research.
Handbook Of Nutraceuticals And Natural Products
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Author : Sreerag Gopi
language : en
Publisher: John Wiley & Sons
Release Date : 2022-06-29
Handbook Of Nutraceuticals And Natural Products written by Sreerag Gopi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-29 with Technology & Engineering categories.
An essential treatment of nutraceuticals and natural products, their preparation techniques, and applications In Handbook of Nutraceuticals and Natural Products: From Concepts to Application, a team of distinguished researchers delivers a one-stop resource describing the preparation techniques and functional uses of nutraceuticals and natural products with a focus on the technologies involved. The book includes coverage of the biological, medicinal, and nutritional properties and applications of functional foods, as well as the advanced technologies used in the extraction and functionalization of nano components and the nanomaterial and nanochemical aspects of the products. The authors discuss developmental research as well as user-level benefits of nutraceuticals and natural products and thoroughly review the market analyses, quality assurance processes, and regulations relevant to nutraceuticals and natural products. They also cover: Thorough introductions to nutraceuticals, functional foods, liposomal technology, prebiotics, and lycopene and its active drug delivery Comprehensive explorations of nutraceutical compounds from marine microalgae and poly lysine as an antimicrobial agent Practical discussions of a nutraceuticals approach to treating cancer-cachexia and early life nutrition and epigenetics In-depth examinations of encapsulation and delivery of nutraceuticals and bioactive compounds by nanoliposomes and tocosomes as promising nanocarriers Perfect for chemists, biochemists, food scientists, and materials scientists, Nutraceuticals and Natural Products: From Concepts to Application will also earn a place in the libraries of medical scientists working in academia or industry, as well as nutritionists, dietitians, and biochemistry graduate students studying nutraceuticals.
Natural Molecules In Neuroprotection And Neurotoxicity
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Author : Marcos Roberto de Oliveira
language : en
Publisher: Elsevier
Release Date : 2023-12-22
Natural Molecules In Neuroprotection And Neurotoxicity written by Marcos Roberto de Oliveira and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-22 with Science categories.
Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. - Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules - Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules - Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells - Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells
Drug Discovery Development
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Author : Bhushan Patwardhan
language : en
Publisher: New India Publishing
Release Date : 2007
Drug Discovery Development written by Bhushan Patwardhan and has been published by New India Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
While biotechnological advances, genomics and high throughput screenings or combinatorial and asymmetric syntheses are opening new opportunities in drug discovery, the industry is facing serious innovation deficit. The total number of new molecules registered per year has dropped in contrast to expected increase. Post marketing failures of blockbuster drugs have become major concerns of industries. On the other side, globally there is a major shift to sue of traditional medicine involving complementary and alternative therapies. Ethnopharmacology and traditional medicines have contributed in past significantly in the process of natural product drug discovery. There are two clear tracks where ethnopharmacology has potential to contribute in future drug research. First, as a discovery engine to provide new targets, leads, and second, use of quality assured and standardized traditional medicines. In this scenario, it is important to understand the mechanisms of drug discovery and pharmaceutical development with a focus on herbal drugs and neutraceutical. This book provides historical perspective, future prospects and significance of ethnopharmacology in drug research. It also provides important steps in botanical drug discovery and development including bioprospecting, quality control, standardization, pharmaceutics, stability, pharmacokinetics, and bioavailability with examples from ethnopharmacology and herbal medicine. One of the important feature of this book is to give an excellent insight to Good Laboratory and Good Clinical Practices along with very useful summary steps involved in filing IND or NDA of botanical products. The book also gives Regulators' perspective of validating claims and how ethnopharmacological or traditional medicines need different approach.
Indopathy For Neuroprotection Recent Advances
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Author : Surya Pratap Singh
language : en
Publisher: Bentham Science Publishers
Release Date : 2022-12-07
Indopathy For Neuroprotection Recent Advances written by Surya Pratap Singh and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-07 with Medical categories.
Degenerative nerve diseases are age-related, progressive and cause irreversible neurological loss that may lead too death. Chronic diseases like amylotrophic lateral sclerosis, Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease are associated with insoluble protein depositions and pose serious health challenges that may intensify in the coming decades. Current therapies only help to alleviate some of the physical or mental symptoms associated with neurodegenerative diseases, although there is currently no remedy for slow disease progression. In recent years, attempts have been made to discover a mechanism for neurodegenerative diseases and prospective treatment that may help mitigate aging effects and prevent these diseases. Natural products have been a constant source of new approaches for the treatment of neurodegenerative diseases, in particular plant alkaloids and polyphenolic compounds. Indopathy for Neuroprotection: Recent Advances highlights herbal treatments that are preferred over conventional treatments in some regions. Book chapters focus on the effects of various medicinal plants that have shown promise in reversing pathological symptoms of neurodegenerative disease and highlight the neuroprotective role of medicinal herbal phytochemicals and their mechanism of action. The book serves as a reference for pharmacology and herbal medicine scholars as well as healthcare workers interested in information about alternative and complementary therapies for neurological disorders.
Concepts Of Alkaloids From Natural Sources
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Author : Rukhsana Rub Pinjari
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2024-10-03
Concepts Of Alkaloids From Natural Sources written by Rukhsana Rub Pinjari and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-03 with Science categories.
Embark on a journey into the captivating world of alkaloids with this book, a thorough guide that explores the most used alkaloid plants, alongside those sourced from animals and marine life. Perfect for students of plant chemistry, herbs, and natural products, this book is crafted to present complex information with simplicity and clarity. Both students and researchers will find it an indispensable reference, providing deep insights into the chemistry and diverse applications of alkaloids. Uncover the intricate science of these natural compounds and expand your knowledge with this essential guide.