Natural Molecules In Neuroprotection And Neurotoxicity
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Natural Molecules In Neuroprotection And Neurotoxicity
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Author : Marcos Roberto de Oliveira
language : en
Publisher: Academic Press
Release Date : 2023-09-01
Natural Molecules In Neuroprotection And Neurotoxicity written by Marcos Roberto de Oliveira and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-01 with Science categories.
Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease.
Medicinal Herbs And Fungi
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Author : Dinesh Chandra Agrawal
language : en
Publisher: Springer Nature
Release Date : 2021-01-21
Medicinal Herbs And Fungi written by Dinesh Chandra Agrawal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-21 with Science categories.
The ever-rising increase in the consumption of medicinal herbs and its products and its exposure in the human population have generated concerns about the potential neurotoxicity of several new and existing botanicals. This book offers an accurate, relevant, and comprehensive coverage of a wide variety of medicinal herbs and fungi affecting the central and peripheral nervous system. It includes review articles that thoroughly describe the benefits and adverse effects of some of the most commonly used medicinal herbs and fungi, and the pathophysiological mechanisms underlying them. The book provides an all-inclusive overview of the diverse aspects of medicinal herbs and fungi related to neurotoxicity and/or neuroprotection, ranging from discussions of cellular and molecular processes and pathology to clinical aspects. The rich compilation brings together thorough and extensive research updates on the advances in the field. The chapters have been contributed by the experienced and eminent academicians, researchers, and scientists working in the field across the globe.
Natural Products And Neuroprotection
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Author : Cristina Angeloni
language : en
Publisher: MDPI
Release Date : 2020-06-17
Natural Products And Neuroprotection written by Cristina Angeloni and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-17 with Science categories.
Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
Discovery And Development Of Neuroprotective Agents From Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2017-05-18
Discovery And Development Of Neuroprotective Agents From Natural Products written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-18 with Science categories.
Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
Natural Molecules In Neuroprotection And Neurotoxicity
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Author : Marcos Roberto de Oliveira
language : en
Publisher: Elsevier
Release Date : 2023-11-24
Natural Molecules In Neuroprotection And Neurotoxicity written by Marcos Roberto de Oliveira and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-24 with Science categories.
Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells
Natural Products And Neuroprotection
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Author : Cristina Angeloni
language : en
Publisher:
Release Date : 2020
Natural Products And Neuroprotection written by Cristina Angeloni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
Neuroprotective Natural Products
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Author : Goutam Brahmachari
language : en
Publisher: John Wiley & Sons
Release Date : 2017-06-19
Neuroprotective Natural Products written by Goutam Brahmachari and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-19 with Medical categories.
Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine. With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.
Neuroprotection
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Author : Matilde Otero-Losada
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-11-26
Neuroprotection written by Matilde Otero-Losada and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-26 with Medical categories.
Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal plants, and essential oils in Alzheimer’s and Parkinson’s; protein misfolding and the neuroprotective potential of vitamin E in cerebral ischemia; and potential new neurological treatments and their mechanisms of action.
Neuroprotection
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Author : Raymond Chuen-Chung Chang
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-08-28
Neuroprotection written by Raymond Chuen-Chung Chang and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-28 with Medical categories.
Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In this book, there are chapters discussing imidazoline ligands and opioid ligands in Alzheimer's disease, the beneficial effects of adenosine A2A receptor antagonist, adrenergic receptor agonists and antagonists modulating microglial responses, and different approaches to achieve neuroprotection against aging-associated macular degeneration. This book will give insights to scientists in the field to stimulate their research, medical professionals to review their clinical practices, and others who would like to learn more about different neuroprotective approaches.
The Benefits Of Natural Products For Neurodegenerative Diseases
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Author : M. Mohamed Essa
language : en
Publisher: Springer
Release Date : 2016-09-20
The Benefits Of Natural Products For Neurodegenerative Diseases written by M. Mohamed Essa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-20 with Medical categories.
Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.