Dispersity Structure And Phase Changes Of Proteins And Bio Agglomerates In Biotechnological Processes
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Dispersity Structure And Phase Changes Of Proteins And Bio Agglomerates In Biotechnological Processes
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Author : Arno Kwade
language : en
Publisher: Springer Nature
Release Date : 2024-09-26
Dispersity Structure And Phase Changes Of Proteins And Bio Agglomerates In Biotechnological Processes written by Arno Kwade and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-26 with Science categories.
This book serves as a comprehensive summary of the priority program SPP 1934, which focused on understanding the dispersity, structure, and phase changes of proteins and bio-agglomerates in biotechnological processes. Through contributions from various research groups, the program explored how sensitive proteins and bio-agglomerates are affected by the process environment during fermentation, downstream processing, and formulation. It investigated these effects across three size scales: microscale, encompassing single proteins, clusters, crystals, and virus-like particles; mesoscale, focusing on cells and cell clusters; and macroscale, examining overall process dynamics. The main objective was to enhance biotechnological process chains by elucidating the mechanical, thermal, and chemical stresses that impact protein and bio-agglomerate structures. By gaining insights into these stressors, the program aimed to enable precise control measures to mitigate denaturation and unfavorable growth of proteins and cells. This compilation seeks to contribute to the optimization of biotechnological processes, facilitating advancements in various industries.
Dispersity Structure And Phase Changes Of Proteins And Bio Agglomerates In Biotechnological Processes
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Author : Arno Kwade
language : en
Publisher: Springer
Release Date : 2024-09-03
Dispersity Structure And Phase Changes Of Proteins And Bio Agglomerates In Biotechnological Processes written by Arno Kwade and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-03 with Science categories.
This book serves as a comprehensive summary of the priority program SPP 1934, which focused on understanding the dispersity, structure, and phase changes of proteins and bio-agglomerates in biotechnological processes. Through contributions from various research groups, the program explored how sensitive proteins and bio-agglomerates are affected by the process environment during fermentation, downstream processing, and formulation. It investigated these effects across three size scales: microscale, encompassing single proteins, clusters, crystals, and virus-like particles; mesoscale, focusing on cells and cell clusters; and macroscale, examining overall process dynamics. The main objective was to enhance biotechnological process chains by elucidating the mechanical, thermal, and chemical stresses that impact protein and bio-agglomerate structures. By gaining insights into these stressors, the program aimed to enable precise control measures to mitigate denaturation and unfavorable growth of proteins and cells. This compilation seeks to contribute to the optimization of biotechnological processes, facilitating advancements in various industries.
Physics Based And Data Driven Mulitiscale Modeling Of The Structural Formation In Macromolecular Systems Band 25
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Author : Philipp Nicolas Depta
language : en
Publisher: Cuvillier Verlag
Release Date : 2024-02-27
Physics Based And Data Driven Mulitiscale Modeling Of The Structural Formation In Macromolecular Systems Band 25 written by Philipp Nicolas Depta and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-27 with categories.
In order to improve knowledge on macromolecular structural formation and self-assembly, this work proposes a physics-based and data-driven multiscale modeling framework capable of describing structural formation on micro-meter and milli-second scales near molecular-level precision. The framework abstracts macromolecules as anisotropic unit objects and models the interactions and environment using data-driven approaches. The models are parameterized in a bottom-up fashion and validated top-down by comparison with literature and collaborator data for self-assembly of three model system: alginate gelation, hepatitis B virus capsids, and the pyruvate dehydrogenase complex.
Interfacial Water A Physical Chemistry Perspective Volume Ii
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Author : Motomu Tanaka
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-19
Interfacial Water A Physical Chemistry Perspective Volume Ii written by Motomu Tanaka and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-19 with Science categories.
Topic Editor Harada receives financial support from AGC Research Collaboration System with the title “Research on the control of biocompatibility based on the analysis of substrate surface”. The other Topic Editors declare no competing interests
Protein Self Assembly
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Author : Jennifer J. McManus
language : en
Publisher: Humana
Release Date : 2020-08-08
Protein Self Assembly written by Jennifer J. McManus and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-08 with Science categories.
This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
Fundamentals Of Cell Immobilisation Biotechnology
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Author : Viktor Nedovic
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Fundamentals Of Cell Immobilisation Biotechnology written by Viktor Nedovic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Cell Immobilisation Biotechnology Biotechnology is divided into two volumes. The first volume is dedicated to fundamental aspects of cell immobilisation while the second volume deals with the diverse applications of this technology. The first volume, Fundamentals of Cell Immobilisation Biotechnology, comprises 26 chapters arranged into four parts: Materials for cell immobilisation/encapsulation, Methods and technologies for cell immobilisation/encapsulation, Carrier characterisation and bioreactor design, and Physiology of immobilised cells: techniques and mathematical modelling.
Downstream Process Technology A New Horizon In Biotechnology
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Author : Krishna Kant Prasad
language : en
Publisher: PHI Learning Pvt. Ltd.
Release Date : 2010-01-30
Downstream Process Technology A New Horizon In Biotechnology written by Krishna Kant Prasad and has been published by PHI Learning Pvt. Ltd. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-30 with Mathematics categories.
Today, biochemical process industry demands fast and economic processes for the partitioning and purification of biomolecules that give high yield and high purity of the product. An integral and cost intensive part of these processes is associated with downstream processing for product isolation and purification. The aim of this comprehensive text is to provide an insightful overview of the whole aspects of downstream processing for biochemical product recovery. Intended for undergraduate and postgraduate students of biotechnology and chemical engineering, this self-contained text includes the chapters based on the recent developments in the industry and academics. It covers the importance of the downstream processing in terms of its relevancy to modern days ever-changing consumer needs, process design criteria relevance to set objectives, and physicochemical factors that help to formulate the strategy to develop a configuration among the raw material, methodology and instruments. This overview is followed by different downstream processing steps. The text concludes with the discussion on stabilization of the product to improve the shelf life of the product. Key Features Includes detailed biological, mathematical, chemical and physical aspects of downstream processing. Distinguishes downstream processing from analytical bioseparation. Contains numerous illustrations and solved problems.
Wet Granular Matter A Truly Complex Fluid
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Author : Stephan Herminghaus
language : en
Publisher: World Scientific
Release Date : 2013-08-29
Wet Granular Matter A Truly Complex Fluid written by Stephan Herminghaus and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-29 with Science categories.
This is a monograph written for the young and advanced researcher who is entering the field of wet granular matter and keen to understand the basic physical principles governing this state of soft matter. It treats wet granulates as an instance of a ternary system, consisting of the grains, a primary, and a secondary fluid. After addressing wetting phenomena in general and outlining the basic facts on dry granular systems, a chapter on basic mechanisms and their effects is dedicated to every region of the ternary phase diagram. Effects of grain shape and roughness are considered as well. Rather than addressing engineering aspects such as existing books on this topic do, the book aims to provide a generalized framework suitable for those who want to understand these systems on a more fundamental basis.
Intensification Of Biobased Processes
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Author : Andrzej Górak
language : en
Publisher: Royal Society of Chemistry
Release Date : 2018-06-18
Intensification Of Biobased Processes written by Andrzej Górak and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-18 with Technology & Engineering categories.
In recent years bioprocessing has increased in popularity and importance, however, bioprocessing still poses various important techno-economic and environmental challenges, such as product yields, excessive energy consumption for separations in highly watery systems, batch operation or the downstream processing bottlenecks in the production of biopharmaceutical products. Many of those challenges can be addressed by application of different process intensification technologies discussed in the present book. The first book dedicated entirely to this area, Intensification of Biobased Processes provides a comprehensive overview of modern process intensification technologies used in bioprocessing. The book focusses on four different categories of biobased products: bio-fuels and platform chemicals; cosmeceuticals; food products; and polymers and advanced materials. It will cover various intensification aspects of the processes concerned, including (bio)reactor intensification; intensification of separation, recovery and formulation operations; and process integration. This is an invaluable source of information for researchers and industrialists working in chemical engineering, biotechnology and process engineering.
Metal Nanoparticles In Microbiology
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Author : Mahendra Rai
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-04-02
Metal Nanoparticles In Microbiology written by Mahendra Rai and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-02 with Science categories.
Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.