Dna Replication Control In Microbial Cell Factories
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Dna Replication Control In Microbial Cell Factories
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Author : Monika Glinkowska
language : en
Publisher: Springer
Release Date : 2014-09-23
Dna Replication Control In Microbial Cell Factories written by Monika Glinkowska and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-23 with Science categories.
This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested. Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.
Efficient Biomanufacturing Via Microbial Cell Factories Volume Ii
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Author : Wei Luo
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-29
Efficient Biomanufacturing Via Microbial Cell Factories Volume Ii written by Wei Luo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with Science categories.
Minimal Cells Design Construction Biotechnological Applications
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Author : Alvaro R. Lara
language : en
Publisher: Springer Nature
Release Date : 2019-12-04
Minimal Cells Design Construction Biotechnological Applications written by Alvaro R. Lara and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-04 with Science categories.
This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Written by leading experts, it presents an in-depth analysis of the current issues and challenges in the field, including recent advances in the generation and characterization of reduced-genome strains generated from model organisms with relevance in biotechnology, and basic research such as Escherichia coli, Corynebacterium glutamicum and yeast. It also discusses methodologies, such as bottom-up and top-down genome minimization strategies, as well as novel analytical and experimental approaches to characterize and generate minimal cells. Lastly, it presents the latest research related to minimal cells of serveral microorganisms, e.g. Bacillus subtilis. The design of biological systems for biotechnological purposes employs strategies aimed at optimizing specific tasks. This approach is based on enhancing certain biological functions while reducing other capacities that are not required or that could be detrimental to the desired objective. A highly optimized cell factory would be expected to have only the capacity for reproduction and for performing the expected task. Such a hypothetical organism would be considered a minimal cell. At present, numerous research groups in academia and industry are exploring the theoretical and practical implications of constructing and using minimal cells and are providing valuable fundamental insights into the characteristics of minimal genomes, leading to an understanding of the essential gene set. In addition, research in this field is providing valuable information on the physiology of minimal cells and their utilization as a biological chassis to which useful biotechnological functions can be added.
Lignocellulosic Biomass And Enzymes
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Author : Rajeev Kumar Kapoor
language : en
Publisher: Springer Nature
Release Date : 2025-05-26
Lignocellulosic Biomass And Enzymes written by Rajeev Kumar Kapoor and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-26 with Science categories.
This book aims to offer comprehensive insights into biomass pretreatment and utilization for recovering value-added products. The book focuses on various topics including lignocellulosic biorefinery challenges, lignolytic enzymes, bioprocess advancements, and emerging industrial applications. It also serves as a knowledge repository on the use of lignocellulosic biomass and enzymes in biotechnological processes, bio-composites development, pulp and paper processing, bio-energy production, biomass detoxification, and more. Chapters of this book cover a broad focus on enzyme technologies, treatment strategies, and the application of industrially important enzymes. Chapters cover the unique features, like the focus on economically feasible treatment strategies, and highlight the book's emphasis on practicality. The book includes aspects of microbial enzymes and biomass overview, advancements in biomass pretreatment, metabolic and genetic engineering approaches, improved process and recovery strategies, eco-friendly bio bleaching in the pulp and paper industry, bioethanol production, and lignocellulose biorefinery. This book is targeted towards a diverse audience including undergraduates, postgraduates, and researchers in academia and industries.
Microbial Physiology
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Author : Albert G. Moat
language : en
Publisher: John Wiley & Sons
Release Date : 2003-03-31
Microbial Physiology written by Albert G. Moat and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-31 with Science categories.
The Fourth Edition of Microbial Physiology retains the logical, easy-to-follow organization of the previous editions. An introduction to cell structure and synthesis of cell components is provided, followed by detailed discussions of genetics, metabolism, growth, and regulation for anyone wishing to understand the mechanisms underlying cell survival and growth. This comprehensive reference approaches the subject from a modern molecular genetic perspective, incorporating new insights gained from various genome projects.
Continuous Biomanufacturing
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Author : Ganapathy Subramanian
language : en
Publisher: John Wiley & Sons
Release Date : 2017-09-12
Continuous Biomanufacturing written by Ganapathy Subramanian and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-12 with Science categories.
This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.
Microbial Cell Factories Engineering For Production Of Biomolecules
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Author : Vijai Singh
language : en
Publisher: Academic Press
Release Date : 2021-02-13
Microbial Cell Factories Engineering For Production Of Biomolecules written by Vijai Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-13 with Science categories.
Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs
Fungal Cell Factories For Sustainable Nanomaterials Productions And Agricultural Applications
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Author : Kamel A Abd-Elsalam
language : en
Publisher: Elsevier
Release Date : 2022-10-26
Fungal Cell Factories For Sustainable Nanomaterials Productions And Agricultural Applications written by Kamel A Abd-Elsalam and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-26 with Business & Economics categories.
Fungal Cell Factories for Sustainable Nanomaterials Productions and Agricultural Applications explores the mycogenic synthesis of many metal nanoparticles, including processing processes, environmental protection, and future perspectives. Nanomaterials, including silver, gold, palladium, copper, zinc, selenium, titanium dioxide, metal sulphide, cellulose, have been formed by major fungal genes, such as mushrooms, Fusarium, Trichoderma, endophytic fungi, and yeast, in addition to lichens. Understanding the exact process involved in the synthesis of nanoparticles and the effects of various factors on the reduction of metal ions can help to improve low-cost strategies for the synthesis and extraction of nanoparticles. Other sections focus on a new framework for the production of nano-antimicrobial, the use of myconanoparticles against plant diseases, post-harvest antibiotics, mycotoxin control and plant pests in addition to certain animal pathogens. Myconanomaterials are well developed with great potential and promise for advanced diagnostics, biosensors, precision farming and targeted smart delivery systems. - Assesses the impact of a variety of copper-based nanostructures on agri-food sectors, addressing the most relevant knowledge gaps - Explores the opportunities that myconanotechnology can provide for industrial applications - Explains the major challenges of applying myconanotechnology at an industrial scale
Alcamo S Fundamentals Of Microbiology
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Author :
language : en
Publisher: Jones & Bartlett Publishers
Release Date :
Alcamo S Fundamentals Of Microbiology written by and has been published by Jones & Bartlett Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Alcamo S Fundamentals Of Microbiology
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Author : Jeffrey C. Pommerville
language : en
Publisher: Jones & Bartlett Publishers
Release Date : 2010-03-08
Alcamo S Fundamentals Of Microbiology written by Jeffrey C. Pommerville and has been published by Jones & Bartlett Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-08 with Science categories.
The ninth edition of award-winning author Jeffrey Pommerville's classic text provides nursing and allied health students with a firm foundation in microbiology, with an emphasis on human disease. An educator himself, Dr. Pommerville incorporates accessible, engaging pedagogical elements and student-friendly ancillaries to help students maximize their understanding and retention of key concepts. Ideal for the non-major, the ninth edition includes numerous updates and additions, including the latest disease data and statistics, new material on emerging disease outbreaks, an expanded use of concept maps, and may other pedagogical features. With an inviting "Learning Design" format and Study Smart notes to students, Alcamo's Fundamentals of Microbiology, Ninth Edition ensures student success as they delve into the exciting world of microbiology.