Down Syndrome Across The Life Span
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Down Syndrome Across The Life Span
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Author : Monica Cuskelly
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Down Syndrome Across The Life Span written by Monica Cuskelly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Psychology categories.
This book promotes a positive message for people with Down syndrome across the world. Living with Down Syndrome is a positive experience for the majority of children and adults with Down syndrome, and for their families. Of course there are difficulties to be faced, but quality of life, from infancy to old age, is determined more by the quality of healthcare, education and social inclusion offered to individuals, than by the developmental difficulties that are associated with Down syndrome. The aim of this book is to bring the latest information on research and good practice to families, practitioners and policy makers in order improve the services available to individuals with Down syndrome in all countries.
International Review Of Research In Mental Retardation
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Author : Richard C. Urbano
language : en
Publisher: Academic Press
Release Date : 2010-10-14
International Review Of Research In Mental Retardation written by Richard C. Urbano and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-14 with Medical categories.
International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, syndromes, etc. of mental retardation. This thematic volume, "Health Issues in Down Syndrome," will cover health issues for individuals across the life span. With the life expectancy of individuals now reaching 60 years or more, it has transformed from an acute condition with a short life span to a chronic condition that needs to be managed over a close to normal life span. The extra chromosome 21 that defines most cases of Down syndrome affects the functioning of many biological processes and organ systems. The cascade of events triggered by the extra chromosome 21 creates a complex set of medical conditions needing to managed over the life span. The ability to manage these conditions has led to an improvement in longevity and quality of life for individuals with Down syndrome. Provides the most recent scholarly research in the study of health issues in Down syndrome A vast range of perspectives is offered, and many topics are covered An excellent resource for academic researchers
Life For Adults With Down Syndrome
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Author : Roy Brown
language : en
Publisher: DSE Enterprises
Release Date : 2004
Life For Adults With Down Syndrome written by Roy Brown and has been published by DSE Enterprises this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Down syndrome categories.
Part of the Down Syndrome Issues and Information Adult Living series, this book takes a lifespan perspective, and considers how experiences in the past and in the present will impact on choices, opportunities and development in the future.
Down Syndrome
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Author : Yvonne Burns
language : en
Publisher: Springer
Release Date : 1993
Down Syndrome written by Yvonne Burns and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Education categories.
People with Down syndrome are increasingly encouraged to participate in community activities, and effective patterns of movement need to be established during early childhood to aid their social integration and acceptance. This book considers the full life cycle of a person with Down syndrome and outlines practices and activities that will foster constructive patterns of movement from infancy through childhood and adolescence to later adulthood.
The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome
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Author : Elizabeth Head
language : en
Publisher: Academic Press
Release Date : 2021-08-31
The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome written by Elizabeth Head and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-31 with Medical categories.
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
Intellectual Disabilities In Down Syndrome From Birth And Throughout Life Assessment And Treatment
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Author : Marie-Claude Potier
language : en
Publisher: Frontiers Media SA
Release Date : 2017-02-24
Intellectual Disabilities In Down Syndrome From Birth And Throughout Life Assessment And Treatment written by Marie-Claude Potier and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-24 with Electronic book categories.
Research on the multiple aspects of cognitive impairment in Down syndrome (DS), from genes to behavior to treatment, has made tremendous progress in the last decade. The study of congenital intellectual disabilities such as DS is challenging since they originate from the earliest stages of development and both the acquisition of cognitive skills and neurodegenerative pathologies are cumulative. Comorbidities such as cardiac malformations, sleep apnea, diabetes and dementia are frequent in the DS population, as well, and their increased risk provides a means of assessing early stages of these pathologies that is relevant to the general population. Notably, persons with DS will develop the histopathology of Alzheimer’s disease (formation of neuritic plaques and tangles) and are at high risk for dementia, something that cannot be predicted in the population at large. Identification of the gene encoding the amyloid precursor protein, its localization to chromosome 21 in the 90’s and realization that all persons with DS develop pathology identified this as an important piece of the amyloid cascade hypothesis in Alzheimer’s disease. Awareness of the potential role of people with DS in understanding progression and treatment as well as identification of genetic risk factors and also protective factors for AD is reawakening. For the first time since DS was recognized, major pharmaceutical companies have entered the search for ameliorative treatments, and phase II clinical trials to improve learning and memory are in progress. Enriched environment, brain stimulation and alternative therapies are being tested while clinical assessment is improving, thus increasing the chances of success for therapeutic interventions. Researchers and clinicians are actively pursuing the possibility of prenatal treatments for many conditions, an area with a huge potential impact for developmental disorders such as DS. Our goal here is to present an overview of recent advances with an emphasis on behavioral and cognitive deficits and how these issues change through life in DS. The relevance of comorbidities to the end phenotypes described and relevance of pharmacological targets and possible treatments will be considerations throughout.
Down Syndrome From Understanding The Neurobiology To Therapy
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Author :
language : en
Publisher: Elsevier
Release Date : 2012-10-16
Down Syndrome From Understanding The Neurobiology To Therapy written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-16 with Medical categories.
Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Multimodal Aac For Individuals With Down Syndrome
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Author : Krista M. Wilkinson
language : en
Publisher:
Release Date : 2020-11-02
Multimodal Aac For Individuals With Down Syndrome written by Krista M. Wilkinson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-02 with categories.
This volume examines the role of multimodal augmentative and alternative communication (AAC) in supporting speech, language, and communication of individuals with Down syndrome, across the lifespan.
Living With Down Syndrome
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Author : Roy I Brown
language : en
Publisher:
Release Date : 2019-07-26
Living With Down Syndrome written by Roy I Brown and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-26 with categories.
This book is written for parents, grandparents, medical staff and caregivers of people with Down syndrome; undergraduate students and young researchers in the field of intellectual disabilities, to give a broad coverage of Down syndrome, showing the latest advances and the changes in its perception, based on practice, personal experience and research.Down syndrome is discussed throughout the lifespan - from birth to old age, in the family and community. The issues of friendship, school and employment as well as health in its broadest sense and the challenges of ageing are reviewed. The application of policies based on both the Convention on the Rights of Persons with Disabilities and the concept of quality of life is also considered. Genetics is often misunderstood, so a simple explanation is given in terms of a condition that occurs naturally as a result of billions of years of evolution.The variability of people with Down syndrome is exemplified with cases from various parts of the world that have been successful in their lives and in their activities. The book is summarised with an optimistic photo essay.It contains an abundant bibliography both historical and recent.This book, originally published in Spanish, was translated to benefit a wider range of readers in need of a rigorous exposition of Down syndrome in accessible terms, including those whose English is their second language.
Down Syndrome
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Author : Lynn Nadel
language : en
Publisher: Wiley-Liss
Release Date : 1995-02-20
Down Syndrome written by Lynn Nadel and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-02-20 with Medical categories.
Recent advances in medicine are allowing people with Down syndrome to live longer and more productively - while at the same time creating new medical and social challenges for them and the people who provide their care. Down Syndrome: Living and Learning in the Community, which was written under the auspices of the National Down Syndrome Society, provides long-awaited, state-of-the-art information and advice about the disease. This book will prove an invaluable tool for parents and health care professionals, enabling people with Down syndrome to cope with the problems they face and participate to the fullest in community life.