The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome


The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome
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The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome


The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome
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Author : Elizabeth Head
language : en
Publisher: Academic Press
Release Date : 2021-08-31

The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome written by Elizabeth Head and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-31 with Medical categories.


The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research



Genetics And Neurobiology Of Down Syndrome


Genetics And Neurobiology Of Down Syndrome
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Author : Bani Bandana Ganguly
language : en
Publisher: Academic Press
Release Date : 2022-08-21

Genetics And Neurobiology Of Down Syndrome written by Bani Bandana Ganguly and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-21 with Medical categories.


Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development. Reviews genetic etiology and mechanisms of trisomy 21 Discusses prenatal screening and genetic counseling, including ethical aspects Explores link between Down Syndrome and susceptibility to Alzheimer’s and early brain aging Covers cognitive and neurological symptoms and other health consequences Identifies future therapeutic developments



Neurodevelopment Aging And Cognition


Neurodevelopment Aging And Cognition
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Author : KNEZEVIC
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Neurodevelopment Aging And Cognition written by KNEZEVIC and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


It was Oscar Wilde who defined the tragedy of old age by saying that " . . . as soon as you are old enough to know better, you don't know anything at all. " As improvements in the quality of health care bring about longer life, our attention has turned from the prolonging of life to the maintenance of involvement in life. In developed nations, a full 100% increase in the ranks of the elderly has appeared and with the benefits of this prolongation have come new and greater needs of the elderly cohort. Our interest is in those processes that may lead to dementia among the elderly, for in dementia we see a thief that robs victims of their memories and their place in life. This text was conceived and developed from an international con ference on neurodevelopment, aging, and cognition; the purpose of this few days a group of experts in these conference was to bring together for a fields from around the world to generate a dialog on common themes and unresolved problems. Our hope was that by keeping the meeting small and informal, we could break through barriers of terminology unique to the areas of developmental neurobiology, neuroscience, cognitive sci ence, and clinical medicine, and have a meaningful discussion on pro cesses that affect the biological integrity and cognitive performance of the aging nervous system.



Down Syndrome From Understanding The Neurobiology To Therapy


Down Syndrome From Understanding The Neurobiology To Therapy
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Author :
language : en
Publisher: Elsevier
Release Date : 2012-10-16

Down Syndrome From Understanding The Neurobiology To Therapy written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-16 with Medical categories.


Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist



The Neurobiology Of Down Syndrome


The Neurobiology Of Down Syndrome
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Author : Charles J. Epstein
language : en
Publisher:
Release Date : 1986

The Neurobiology Of Down Syndrome written by Charles J. Epstein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Down syndrome categories.




Down Syndrome And Alzheimer S Disease


Down Syndrome And Alzheimer S Disease
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Author : Vee Prasher
language : en
Publisher: CRC Press
Release Date : 2018-12-14

Down Syndrome And Alzheimer S Disease written by Vee Prasher and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-14 with Medical categories.


This is the first book in the field to address the underlying biological abnormalities of Dementia in Alzheimer’s Disease (DAD) in people with Down syndrome. It brings together research findings relating to the neuropathology, genetics, blood markers and neurophysiology of Alzheimer’s disease in older adults with Down syndrome. Down Syndrome and Alzheimer’s Disease presents vital information to medical professionals who provide clinical care to people with Alzheimer’s disease and Down syndrome. It will also be of great benefit to researchers with an interest in Alzheimer’s disease and Down syndrome and academics researching ageing issues in people with Down Syndrome. It complements Alzheimer's Disease and Dementia in Down Syndrome and Intellectual Disabilities by the same author.



Down Syndrome Neurodegeneration And Dementia


Down Syndrome Neurodegeneration And Dementia
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Author : Sylvia Eva Perez
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-27

Down Syndrome Neurodegeneration And Dementia written by Sylvia Eva Perez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-27 with Science categories.




Handbook Of The Neuroscience Of Aging


Handbook Of The Neuroscience Of Aging
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Author : Patrick R. Hof
language : en
Publisher: Academic Press
Release Date : 2010-05-22

Handbook Of The Neuroscience Of Aging written by Patrick R. Hof and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-22 with Medical categories.


A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008). The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers. This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology. * The most comprehensive source of up-to-date data on the neurobiology of aging, review articles cover: normal, sensory and cognitive aging; neuroendocrine, structural and molecular factors; and fully address both patholgy and intervention * Chapters represent an authoritative selection of relevant material from the most comprehensive source of information about neuroscience ever assembled, (Encyclopedia of Neuroscience), synthesizing information otherwise dispersed across a number of journal articles and book chapters, and saving researchers the time consuming process of finding and integrating this information themselves * Offering outstanding scholarship, each chapter is written by an expert in the topic area and over 20% of chapters feature international contributors, (representing 11 countries) * Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions * Fully explores various pathologies associated with the aging brain (Alzheimer's, dementia, Parkinson's, memory disorders, stroke, Down's syndrome, etc.) * Coverage of disorders and key interventions makes the volume relevant to clinicians as well as researchers * Heavily illustrated with over 100 color figures



Alzheimer S Disease Down S Syndrome And Aging


Alzheimer S Disease Down S Syndrome And Aging
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Author : F. Marott Sinex
language : en
Publisher:
Release Date : 1982

Alzheimer S Disease Down S Syndrome And Aging written by F. Marott Sinex and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with categories.




Dementia Aging And Intellectual Disabilities


Dementia Aging And Intellectual Disabilities
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Author : Matthew P. Janicki
language : en
Publisher: Psychology Press
Release Date : 1999

Dementia Aging And Intellectual Disabilities written by Matthew P. Janicki and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Aged people with mental disabilities categories.


First Published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.