The Neurobiology Of Down Syndrome
DOWNLOAD
Download The Neurobiology Of Down Syndrome PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get The Neurobiology Of Down Syndrome book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
The Neurobiology Of Down Syndrome
DOWNLOAD
Author : Charles J. Epstein
language : en
Publisher:
Release Date : 1986
The Neurobiology Of Down Syndrome written by Charles J. Epstein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Down syndrome categories.
Down Syndrome From Understanding The Neurobiology To Therapy
DOWNLOAD
Author :
language : en
Publisher: Elsevier
Release Date : 2012-10-16
Down Syndrome From Understanding The Neurobiology To Therapy written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-16 with Medical categories.
Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Genetics And Neurobiology Of Down Syndrome
DOWNLOAD
Author : Bani Bandana Ganguly
language : en
Publisher: Academic Press
Release Date : 2022-08-21
Genetics And Neurobiology Of Down Syndrome written by Bani Bandana Ganguly and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-21 with Medical categories.
Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development. Reviews genetic etiology and mechanisms of trisomy 21 Discusses prenatal screening and genetic counseling, including ethical aspects Explores link between Down Syndrome and susceptibility to Alzheimer’s and early brain aging Covers cognitive and neurological symptoms and other health consequences Identifies future therapeutic developments
The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome
DOWNLOAD
Author : Elizabeth Head
language : en
Publisher: Academic Press
Release Date : 2021-08-31
The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome written by Elizabeth Head and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-31 with Medical categories.
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
The Molecular Biology Of Down Syndrome
DOWNLOAD
Author : G. Lubec
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-01
The Molecular Biology Of Down Syndrome written by G. Lubec and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-01 with Medical categories.
This book contains updated reviews and original research work on Down Syndrome focussing on brandnew results in neurobiology, in particular results on gene hunting (subtractive hybridization, differential display) and neurochemistry. The book provides new data such as a subtractive library of Down Syndrome brain showing cDNAs that are overexpressed or downregulated and can be regarded as a source for further research on the preliminary transcriptional data given. A 2D-electrophoretic map of human brain proteins including Down Syndrome brain protein expression established by in-gel-digestion of spots with subsequent MALDI-identification provides the scientific basis for protein work to the neuroscientist. Altogether, the book provides a series of new candidate genes possibly involved in Down Syndrome neurobiology, tools for neuroscience studies on Down Syndrome brain thus serving as a manual and updated views and aspects on Down Syndrome pathobiology.
Alzheimer Disease Down Syndrome And Their Relationship
DOWNLOAD
Author : Joseph Maurice Berg
language : en
Publisher: Oxford University Press, USA
Release Date : 1993
Alzheimer Disease Down Syndrome And Their Relationship written by Joseph Maurice Berg and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Literary Criticism categories.
Unique, up-to-date and comprehensive, this book considers in depth the remarkable association between Down Syndrome and Alzheimer disease. It provides overviews of each condition, followed by detailed accounts and analyses of hypotheses that attempt to account for the presence of Down Syndrome as a risk factor for Alzheimer disease. The data and discussions presented, including practical diagnostic and management recommendations, will be vital for health professionals involved in caring for adults with Down Syndrome, and for researchers exploring biological and behavioral aspects of the intriguing link between the two disorders.
Advances In Cellular Neurobiology
DOWNLOAD
Author : Sergey Fedoroff
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Advances In Cellular Neurobiology written by Sergey Fedoroff and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Nature categories.
Advances in Cellular Neurobiology, Volume 4 focuses on the central nervous system. This book is divided into three main sections—cell differentiation and interaction, aging and pathology, and methodologies. The topics discussed include advances in the neurobiology of oligodendroglia; neuronal differentiation in reaggregate cell cultures; and morphological aspects of brain edema. The cell biological aspects of Down's syndrome; isolation and culture of cells of the dorsal root ganglia; and growth requirements of neural cells in vitro are also deliberated in this text. This publication is intended for neurologists, but is also beneficial to students researching on the anatomy and functional relation of the brain and spinal cord.
Comprehensive Developmental Neuroscience Neural Circuit Development And Function In The Heathy And Diseased Brain
DOWNLOAD
Author : A.B. Bowman
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-06
Comprehensive Developmental Neuroscience Neural Circuit Development And Function In The Heathy And Diseased Brain written by A.B. Bowman and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Medical categories.
Preclinical Research In Down Syndrome Insights For Pathophysiology And Treatments
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2020-02-10
Preclinical Research In Down Syndrome Insights For Pathophysiology And Treatments written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-10 with Science categories.
Preclinical Research in Down Syndrome: From Bench to Bedside, Volume 251, the latest release in the Progress in Brain Research series, highlights new advances in the field. Chapters in this updated release include Exploring genetic and epigenetic mechanisms underlying cognitive deficits in Dow syndrome, The trisomy paradox: gene expression dysregulation domains, the Influence of allelic differences in mouse models of Down syndrome, Modelling Down syndrome in cells: From stem cells to organoids, Modelling Down syndrome in animals from the early stage to the new generation of models, Mapping behavioral landscapes in Down syndrome animal models, and more. Presents content by renowned authors who review the state-of-the-art in preclinical research and provide their views and perspectives for the future of the field Provides extensively referenced chapters, thus giving readers a comprehensive list of resources on topics covered Includes comprehensive and in-depth background information written in a clear form that is accessible to both specialists and non-specialists
Trisomy 21
DOWNLOAD
Author : André Frank Zimpel
language : en
Publisher: Vandenhoeck & Ruprecht
Release Date : 2016-07-11
Trisomy 21 written by André Frank Zimpel and has been published by Vandenhoeck & Ruprecht this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-11 with Education categories.
For a long time, it was assumed that a genetic disposition such as trisomy 21 enables predictions to be made about overall personality development. But, who could have ever imagined that people with trisomy 21 (Down syndrome) would also be capable of earning a university degree? We studied 1,294 people with trisomy 21. The results showed that people with trisomy 21 benefit more from abstract learning than their neurotypical counterparts. Two-year-olds with the syndrome first learn to read and only then to speak and will understand algebra better than arithmetic. Ignorance of neurodiversity inevitably leads to learning difficulties when these people are forced to learn at the same pace as others. This applies to autism and trisomy 21 to the same extent. That is why this book advocates the recognition of trisomy 21 as a variant in the spectrum of human neurodiversity.