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Drug Delivery Applications Of Noninvasive Imaging


Drug Delivery Applications Of Noninvasive Imaging
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Drug Delivery Applications Of Noninvasive Imaging


Drug Delivery Applications Of Noninvasive Imaging
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Author : Chun Li
language : en
Publisher: John Wiley & Sons
Release Date : 2013-10-14

Drug Delivery Applications Of Noninvasive Imaging written by Chun Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-14 with Medical categories.


Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics, biodistribution, bioavailability, local concentration, and clearance of drug substances for the treatment of human disease, most notably cancer. Written by a team of international experts, this book examines the use of quantitative imaging techniques in designing and evaluating novel drug delivery systems and applications. Drug Delivery Applications of Noninvasive Imaging offers a full arsenal of tested and proven methods, practices and guidance, enabling readers to overcome the many challenges in creating successful new drug delivery systems. The book begins with an introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitative analysis Imaging drugs and drug carriers at the site of action, including low-molecular weight radiopharmaceuticals, peptides and proteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routes other than intravenous injection, such as pulmonary and oral delivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drug development and drug delivery Chapters are based on a thorough review of the current literature as well as the authors' firsthand experience working with imaging techniques for the development of novel drug delivery systems. Presenting state-of-the-technology applications of imaging in preclinical and clinical evaluation of drug delivery systems, Drug Delivery Applications of Noninvasive Imaging offers cost-effective strategies to pharmaceutical researchers and students for developing drug delivery systems that accurately target a broad range of disease conditions.



Magnetic Nanoparticles In Human Health And Medicine


Magnetic Nanoparticles In Human Health And Medicine
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Author : Costica Caizer
language : en
Publisher: John Wiley & Sons
Release Date : 2021-11-22

Magnetic Nanoparticles In Human Health And Medicine written by Costica Caizer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-22 with Science categories.


Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, ­biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer ­therapeutics—featuring discussion of current problems, ­proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.



Nanotheranostics For Personalized Medicine


Nanotheranostics For Personalized Medicine
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Author : Simona Mura
language : en
Publisher: World Scientific
Release Date : 2016-02-22

Nanotheranostics For Personalized Medicine written by Simona Mura and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-22 with Medical categories.


The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome. Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine. This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field. Contents:Combining Imaging and Drug Delivery for the Treatment of Severe Diseases (Simona Mura and Patrick Couvreur)Increased Sensitivity for Medical Imaging Using Non-Ionizing Nanomedicine as Contrast Agents (Cyrille Richard, Bich-Thuy Doan and Nathalie Mignet)MRI T2 Weighted Theranostic Nanodevices and Chemotherapy (Sophie Laurent, Luce Vander Elst, Dimitri Stanicki and Robert N Muller)MRI T1 Weighted Theranostic Nanodevices (Lucie Sancey, François Lux, Géraldine Le Duc, Sabin Carme and Olivier Tillement)Optical Imaging and Chemotherapy (Guillaume Bort, Simona Mura and Patrick Couvreur)Plasmonic Nanoparticles-Coated Microbubbles for Theranostic Applications (Mark A Borden, Jacob D Dove and Todd W Murray)Contribution of Nuclear Medicine to Cancer Nanotheranostics (Thomas Lars Andresen, Anncatrine L Petersen, Anders E Hansen and Jonas R Henriksen)Nanotheranostics in Gene Therapy (Madhura Deshpande, Shravan Kumar Sriraman and Vladimir Torchilin)Nanotheranostics in Cardiovascular Diseases (Maya Juenet, Mariana Varna, Cédric Chauvierre and Didier Letourneur)Stimuli-Responsive Nanotheranostics (Basit Yameen, Jun Wu, Critian Vilos, Andrew Whyte David Werstler, Lori Pollit and Omid C Farokhzad)Advancing the Practical Clinical Utility in Personalized Medicine: Capabilities and Lessons Learned for Pharmacology and Pharmaceutics (Ioannis S Vizirianakis, Christina Karavasili, Elsa P Amanatiadou and Dimitrios G Fatouros) Readership: Advanced undergraduates, graduates, as well as experimental researchers in academia or the industry with an interest in this emerging concept in the nanomedicine world. Key Features:This book presents an integrated and transdisciplinary description of an emerging concept in the world of nanomedicine: nanotheranosticsThis work is one of the few dedicated to nanotheranostics and its applicationsWritten by well-recognized experts in academia, this book would offer to the reader a clear overview of the progresses in the field of nanotheranostics and their fundamental contribution to the field of personalized medicineReading this book would open the way to further improvements and to the possible clinical translation of the nanotheranostics concept in the not-too-distant futureKeywords:Bioengineering;Nanomedicine & Nanobiology;Biomedical Engineering;Medical Imaging;Therapy



Nanomedicine For Deep Tissue High Resolution Bio Imaging And Non Invasive Therapy


Nanomedicine For Deep Tissue High Resolution Bio Imaging And Non Invasive Therapy
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Author : Michael Ming-Yuan Wei
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-12

Nanomedicine For Deep Tissue High Resolution Bio Imaging And Non Invasive Therapy written by Michael Ming-Yuan Wei and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-12 with Science categories.


Dr Ming-Yuan Wei currently holds a pending U.S. Patent Application entitled “Systems and Methods for High-Resolution Imaging”. All other Guest Editors have no other competing interests to declare with regards to the Topic subject.



Handbook Of Non Invasive Drug Delivery Systems


Handbook Of Non Invasive Drug Delivery Systems
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Author : Vitthal S. Kulkarni
language : en
Publisher: Elsevier
Release Date : 2009-12-31

Handbook Of Non Invasive Drug Delivery Systems written by Vitthal S. Kulkarni and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-31 with Medical categories.


With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery. The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.



Theranostics And Image Guided Drug Delivery


Theranostics And Image Guided Drug Delivery
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Author : Maya Thanou
language : en
Publisher: Royal Society of Chemistry
Release Date : 2018-01-02

Theranostics And Image Guided Drug Delivery written by Maya Thanou and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-02 with Science categories.


Molecular imaging of drugs or drug carriers is a valuable tool that can provide important information on spatiotemporal distribution of drugs, allowing improved drug distribution at target sites. Chemically labelled drugs can be used to both diagnose and treat diseases. This book introduces the topic of image guided drug delivery and covers the latest imaging techniques and developments in theranostics, highlighting the interdisciplinary nature of this field as well as its translational ability. These technologies and techniques hold potential for individualised, safer therapies. The book introduces the chemistry behind labelling drugs or drug carriers for imaging. It then discusses current scientific progress in the discovery and development of theranostic agents as well as the latest advances in triggered drug delivery. Novel imaging techniques that can be combined with therapeutics are presented, as well as results and findings from early clinical trials. This text will provide postgraduates and researchers in various disciplines associated with drug discovery, including chemistry, device engineering, oncology, neurology, cardiology, imaging, and nanoscience, an overview of this important field where several disciplines have been combined to improve treatments. Readers will be introduced to techniques that can be translated to the clinic and be applied widely.



Mri Guided Focused Ultrasound Surgery


Mri Guided Focused Ultrasound Surgery
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Author : Ferenc A. Jolesz
language : en
Publisher: CRC Press
Release Date : 2007-09-26

Mri Guided Focused Ultrasound Surgery written by Ferenc A. Jolesz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-26 with Medical categories.


MRI-Guided Focused Ultrasound Surgery will be the first publication on this new technology, and will present a variety of current and future clinical applications in tumor ablation treatment. This source helps surgeons and specialists evaluate, analyze, and utilize MRI-guided focused ultrasound surgery - bridging the gap between phase 3 clinical tr



Noninvasive Monitoring Of Drug Bioavailability By Tissue Impedance Measurement


Noninvasive Monitoring Of Drug Bioavailability By Tissue Impedance Measurement
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Author : Pasquale Arpaia
language : en
Publisher: CRC Press
Release Date : 2022

Noninvasive Monitoring Of Drug Bioavailability By Tissue Impedance Measurement written by Pasquale Arpaia and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Medical categories.


"The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications"--



Image Guided Therapy Surgery And Drug Delivery


Image Guided Therapy Surgery And Drug Delivery
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Author : Keyvan Farahani
language : en
Publisher:
Release Date : 2018

Image Guided Therapy Surgery And Drug Delivery written by Keyvan Farahani and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.




Unravelling Cancer Signaling Pathways A Multidisciplinary Approach


Unravelling Cancer Signaling Pathways A Multidisciplinary Approach
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Author : Kakoli Bose
language : en
Publisher: Springer Nature
Release Date : 2019-11-25

Unravelling Cancer Signaling Pathways A Multidisciplinary Approach written by Kakoli Bose and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-25 with Medical categories.


Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.