Drug Targeting And Delivery
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Targeted Drug Delivery Concepts And Design
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Author : Padma V. Devarajan
language : en
Publisher: Springer
Release Date : 2014-12-08
Targeted Drug Delivery Concepts And Design written by Padma V. Devarajan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Medical categories.
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.
Drug Targeting And Stimuli Sensitive Drug Delivery Systems
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Author : Alexandru Mihai Grumezescu
language : en
Publisher: William Andrew
Release Date : 2018-05-21
Drug Targeting And Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-21 with Science categories.
Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy
Targeted Drug Delivery
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Author : Rudolph L. Juliano
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Targeted Drug Delivery written by Rudolph L. Juliano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The chapters in this volume describe a powerful emerging approach for the therapy of disease. Targeted drug delivery, that is control of the kinetic behavior, tissue distribution, and subcellular localization of pharmaco logically active agents, offers an important means for improving the efficacy of a wide variety of drug therapies. This is particularly true for therapeutic approaches based on newer agents which are the products of recombinant DNA research. These agents, be they peptides, proteins, or oligonucleotides, tend to be larger, more complex, and less stable than traditional drugs. Thus they stand to benefit most from drug delivery systems which can protect them from premature degradation and which can carry them to critical target sites in the body. This volume examines several important aspects of the current state of drug delivery research; it also attempts to project future directions for this field. Successful approaches to drug targeting are based, first of all, on a sophisticated understanding of the biological barriers encountered by the drug-carrier complex as it moves from the portal of administration to the ultimate target site. A second aspect of successful drug delivery is appro priate matching of the disease entity with the pharmacologically active substance and with the delivery system. Thus it is important to be aware of the variety of delivery technologies which currently exist and to be sensitive to their strengths and limitations.
Targeted Drug Delivery
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Author : Rachael W. Sirianni
language : en
Publisher: Humana Press
Release Date : 2018-07-27
Targeted Drug Delivery written by Rachael W. Sirianni and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-27 with Medical categories.
This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.
Drug Delivery And Targeting
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Author : Anya M. Hillery
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Drug Delivery And Targeting written by Anya M. Hillery and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.
The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of disease. However, such potential is severely compromised by significant obstacles to delivery of these drugs in vivo. These obstacles are often so great that effective drug delivery and targeting is now recognized as the key to effective development of many therapeutics. Advanced drug delivery and targeting can offer significant advantages to conventional drugs, such as increased efficiency, convenience, and the potential for line extensions and market expansion. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including: *Methods to optimize therapeutic efficacy, and the related commercial implications *Difficulties with drug absorption, unwanted distribution and premature inactivation / elimination *Attempts to minimize toxicity or alter immunogenicity *Methods to achieve rate-controlled drug release and effective drug targeting *Novel and established routes of delivery *Use of new generation technologies such as biosensors, microchips, stimuli-sensitive hydrogels and plasmid-based gene therapy This volume is indispensable for pharmaceutical students, scientists and researchers.
Smart Drug Delivery System
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Author : Ali Demir Sezer
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-02-10
Smart Drug Delivery System written by Ali Demir Sezer and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-10 with Medical categories.
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
Targeted Delivery Of Small And Macromolecular Drugs
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Author : Ajit S. Narang
language : en
Publisher: CRC Press
Release Date : 2010-05-12
Targeted Delivery Of Small And Macromolecular Drugs written by Ajit S. Narang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-12 with Medical categories.
Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery technologies that utilize both systemic and local rou
Fasttrack Pharmaceutics
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Author : Yvonne Perrie
language : en
Publisher: Pharmaceutical Press
Release Date : 2012
Fasttrack Pharmaceutics written by Yvonne Perrie and has been published by Pharmaceutical Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
"Pharmaceutics - Drug delivery and targeting focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs."--Page 4 of cover.
Targeted Controlled Drug Delivery Novel Carrier Systems Hb
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Author : Vyas; Khar
language : en
Publisher:
Release Date : 2006-02-01
Targeted Controlled Drug Delivery Novel Carrier Systems Hb written by Vyas; Khar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-01 with Drug delivery systems categories.
Drug Targeting And Delivery
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Author : H.E. Junginger
language : en
Publisher: CRC Press
Release Date : 1992-10-31
Drug Targeting And Delivery written by H.E. Junginger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-31 with Medical categories.
This is a review of the structure and function of biological membranes and other cellular barriers used in drug transport. It discusses a range of concepts for drug delivery systems, treating the routes of drugs with regard to their characteristics: function, structure, uptake, mechanism and effect. The book also explores the interface between pharmaceutical technology and physiological principles in drug design, a field of increased importance to industry.