Drugs For The Control Of Epilepsy
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Drugs For The Control Of Epilepsy
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Author : Carl L. Faingold
language : en
Publisher: CRC Press
Release Date : 2019-06-04
Drugs For The Control Of Epilepsy written by Carl L. Faingold and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
Originally published in 1991. This book brings together the ideas of an international group of experts on clinical and experimental epilepsy. These authors consider how antiepileptic drugs may act on elements of neuronal networks to reduce seizure incidence and severity. The book addresses such topics as the four general classes of anticonvulsant drug mechanisms, major epilepsy models, the proposed mechanisms of action of major antiepileptic drugs, and the clinical use of antiepileptic drugs in the treatment of various forms of human epilepsy. This volume is special for its focus on the neuronal network approach to epilepsy, as well as for its comprehensive review and integration of human and animal data. Neurologists, pharmacologists, psychiatrists, and other investigators actively working on epilepsy research will find this book to be a useful, thought-provoking reference volume.
Handbook Of Epilepsy Treatment
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Author : Simon Shorvon
language : en
Publisher: John Wiley & Sons
Release Date : 2010-12-03
Handbook Of Epilepsy Treatment written by Simon Shorvon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-03 with Medical categories.
Make your way through the epilepsy maze Epilepsy is a complex neurological condition. There are many modern treatment options, and treatment should nowadays be tailored to an individual patient. But identification of the best therapy can be a labyrinthine process. The Handbook of Epilepsy Treatment provides a practical pathfinder for treating epilepsy based on published evidence and the author’s 30 years of specialist clinical experience. Direct in style but comprehensive in content, with ample tables and summaries, the Handbook of Epilepsy Treatment covers: Treatment of the different forms and causes of epilepsy Treatment in the different commonly encountered clinical situations Treatment in children, in adults, in the elderly, in women, in epilepsy syndromes and in those with special needs and requirements Epilepsy drugs – their pharmacology, kinetics, side effects, effectiveness and practical usage in the clinic Epilepsy surgery – the various types, the indications, assessment and outcome A succinct pharmacopeia summarizes the entire range of anti-epileptic medications with emphasis on effective prescribing in the clinical setting. The Handbook of Epilepsy Treatment will help you and your patient find the best path to control epilepsy for each individual’s situation.
Medication For Epilepsy
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Author : Epilepsy Society
language : en
Publisher: Epilepsy Society
Release Date : 2014-01-31
Medication For Epilepsy written by Epilepsy Society and has been published by Epilepsy Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-31 with categories.
Medication booklet The booklet covers issues around taking anti-epileptic drugs (AEDs) for epilepsy. The information applies to all ages. It covers topics such as: •what AEDs are and what they do; •how AEDs are chosen; •how treatment is started; •making decisions about taking medication or not; •side effects and interactions; •medication adherence including reasons why someone might not want to, or be able to take, medicines, what might help to take medication including practical things like drug wallets and pill crushers, and strategies for remembering medication; •treatment plans; •how medication is monitored; and •what happens if medication does not work.
Epilepsy
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Author : Adrienne Richard
language : en
Publisher: Bloomsbury Publishing USA
Release Date : 2009-05-29
Epilepsy written by Adrienne Richard and has been published by Bloomsbury Publishing USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-29 with Medical categories.
This book is a unique collaboration between a gifted writer with epilepsy and a skilled physician who has brought new insight into the treatment of this condition. At the age of twenty-six, when Adrienne Richard was seven months pregnant, she was diagnosed with epilepsy. For years she took anticonvulsant drugs to control her seizures, but she wanted to wean herself from the powerful drugs if she could. During the first ten years without medication she had only one seizure. Her goal was to live seizure-free. Ms. Richard practiced yoga, biofeedback, and mind/body techniques in the eighties to help her reach that goal. While writing an article for a magazine based in California, she learned of Dr. Joel Reiter, who was exploring epilepsy self-care in his clinical practice and through his groundbreaking research. Epilepsy: A New Approach combines Adrienne Richard's own inspiring story of overcoming a debilitating condition with Dr. Reiter's up-to-the-minute medical knowledge of diagnosis and treatment. This self-help program offers people with epilepsy and those who love them a chance to regain control of their lives.
The Treatment Of Epilepsy
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Author : Simon Shorvon
language : en
Publisher: John Wiley & Sons
Release Date : 2015-09-15
The Treatment Of Epilepsy written by Simon Shorvon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-15 with Medical categories.
Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries
Orphan Drugs In Epilepsy
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Author : M. Nikanorova
language : en
Publisher: John Libbey Eurotext
Release Date : 2013-09-18
Orphan Drugs In Epilepsy written by M. Nikanorova and has been published by John Libbey Eurotext this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-18 with categories.
All the necessary information on 6 molecules called “orphan drugs” used in the treatment of some epileptic syndromes. More than half of epilepsies start before the age of 20 years and nearly 25% of them are refractory. Two problems arise: - It is essential to treat them so that brain development continues as normally as possible. - There are few drugs available. This work outlines 6 molecules in detail that are specifically used in epileptic encephalopathies. Every aspect of these molecules is discussed, including drug development, indication, efficacy, cost, etc. Drafted by international experts in the field of epileptology, this book provides all the necessary information on orphan drugs and their clinical use.
Pharmacoresistance In Epilepsy
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Author : Luisa Rocha
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08
Pharmacoresistance In Epilepsy written by Luisa Rocha and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
Although more than 10 new antiepileptic drugs have been developed in the past decade, epilepsy remains resistant to drug therapy in about one third of patients, many of whom struggle with the disease their entire lives. Managing these patients is a challenge and requires a structured multidisciplinary approach. The book includes chapters on all issues related to pharmacoresistance in epilepsy and describes recent developments in the pathogenesis and treatment of this disorder. It addresses abnormalities in inhibitory mechanisms, epilepsy-related changes to the immune system, development of pharmacoresistance caused by chronic exposure to antiepileptic drugs, and novel therapeutic strategies for preventing or slowing down the progression of the disease. Clinicians and basic scientists alike will find up-to-date information on the development of pharmacoesistance, as well as reviews of mechanisms associated with epilepsy that may help them consider novel strategies for preventing the development of pharmacoresistance in the first place. The book also features information on new therapeutic strategies for control of epilepsy, such as transcutaneous electrical stimulation and virtual screening of new antiepileptic drugs. Pharmacoresistance in Epilepsy: From Genes and Molecules to Promising Therapies is useful to anyone working in the field, whether they’re studying epilepsy in the lab or treating it in a doctor’s office.”
Antiepileptic Drugs
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Author : René H. Levy
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2002
Antiepileptic Drugs written by René H. Levy and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The thoroughly revised, updated Fifth Edition of this classic is the m ost comprehensive, current, and authoritative reference on all anticon vulsants available today. This edition features detailed profiles of n ewer drugs--including levetiracetam, oxcarbazepine, tiagabine, topiram ate, and zonisamide--and new chapters on use of antiepileptic drugs in children and during pregnancy. Drugs are covered in alphabetical ord er and in an easy-to-follow format: mechanisms of action; chemistry, b iotransformation, and pharmacokinetics; interactions; clinical efficac y and use; and adverse effects. Coverage of clinical use includes none pileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.
Effectiveness And Safety Of Antiepileptic Medications In Patients With Epilepsy
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Author : U. S. Department of Health and Human Services
language : en
Publisher: Createspace Independent Pub
Release Date : 2013-04-16
Effectiveness And Safety Of Antiepileptic Medications In Patients With Epilepsy written by U. S. Department of Health and Human Services and has been published by Createspace Independent Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-16 with Medical categories.
Epilepsy is a clinical phenomenon in which a person has recurrent seizures due to a chronic underlying process. Approximately 1 to 3 percent of people in the United States will develop epilepsy over the course of their lives. Epilepsy begins most commonly during the first 9 years of life, plateaus over the next 30 years, dips in patients 40 to 59 years of age, and then rises again in the elderly. Seizures in epilepsy can result in status epilepticus, a life-threatening unrelenting seizure, or can result in car accidents or falls that can lead to morbidity or mortality. In addition, uncontrolled seizures can result in patients losing their jobs or driving privileges. The main three types of seizures in patients with epilepsy include partial, generalized, and unclassified. There are several distinct subtypes of seizures. Since 1993, the Food and Drug Administration (FDA) has approved several newer antiepileptic drugs (felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, oxcarbazepine, pregabalin, rufinamide, tiagabine, topiramate, vigabatrin, zonisamide) for the treatment of epilepsy. This offered clinicians and patients many new options over the older antiepileptic medications that were approved between 1953 and 1983 (phenytoin, 1953; primidone, 1954; ethosuximide, 1960; carbamazepine, 1968; clonazepam, 1975; divalproex, 1978; valproic acid, 1983). The comparative benefits and harms of older versus newer antiepileptic drugs have been assessed in numerous randomized controlled trials with varying results. Another important issue in the management of epilepsy is generic substitution of innovator antiepileptic medications. The American Academy of Neurology has issued two position papers stating that there is concern with generic antiepileptic medication substitution and that physicians should specifically approve all generic substitutions. . The Italian League Against Epilepsy established a working group on generic products in epilepsy treatment. It concluded that generic medications offer a valuable and cost-effective choice in the management of epilepsy but that generic substitution is not recommended in patients who achieve seizure remission on an innovator product. The FDA and the American Society of Health-System Pharmacists do not share the view that antiepileptic medications, or other narrow therapeutic index medications (medications where the difference between the minimum effective and minimum toxic concentrations are close together), should be treated differently as it pertains to generic substitution. This CER utilized data on benefits and harms from direct comparative studies of newer versus older or innovator versus generic antiepileptic medications in patients with epilepsy. Key Question 1: In patients with epilepsy, what is the comparative effectiveness/efficacy of antiepileptic medications on health outcomes: mortality, hospitalizations, office/emergency department visits, composite endpoint of medical service utilization, health-related quality of life, seizures, secondary seizure injury, status epilepticus, loss of driver's license, and loss of employment? Key Question 2: In patients with epilepsy, what is the comparative effectiveness/efficacy of antiepileptic medications on intermediate outcomes: pharmacokinetics, the comparative dose of medication needed to control seizures, and switchback rates? Key Question 3: In patients with epilepsy, what is the comparative impact of antiepileptic medications on serious adverse events such as neurological adverse effects, hypotension, rash, suicidal ideation, mood and cognition, bone density, and cosmetic adverse effects? Key Question 4: In patients with epilepsy, what are the comparative benefits or harms for antiepileptic medications in subgroups of patients differentiated by seizure etiology, seizure type, gender, ethnicity, patient age, and patient pharmacogenetic profile; and by types of antiepileptic medication?
Drug Trials In Epilepsy
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Author : Dieter Schmidt
language : en
Publisher: CRC Press
Release Date : 1998-06-01
Drug Trials In Epilepsy written by Dieter Schmidt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-06-01 with Medical categories.
With the proliferation of antiepileptic drugs over the last decade, clinicians are increasingly looking for guidance from clinical trials to help them decide the best drug to treat an individual suffering from epilepsy As there are different trials for different purposes and regulatory guidelines can differ from country to country, there is a bewildering array of guidelines This book offers a guide of drug trials in epilepsy in an effort to help clinicians choose the best drugs for their patients