Emerging Functions Of Septins Volume Ii
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Emerging Functions Of Septins Volume Ii
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Author : Manoj B. Menon
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-12
Emerging Functions Of Septins Volume Ii written by Manoj B. Menon and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Science categories.
Emerging Functions Of Septins
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Author : Manoj B. Menon
language : en
Publisher: Frontiers Media SA
Release Date : 2017-10-10
Emerging Functions Of Septins written by Manoj B. Menon and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-10 with categories.
Together with the microfilament, microtubule and intermediate-filament networks, septins constitute an integral part of the eukaryotic cytoskeleton. Historically identified as proteins critical for septum formation in the budding yeast Saccharomyces cerevisiae, septin family GTPases are expressed and participate in the process of cytokinesis in most eukaryotes except higher plants. More than a dozen septin genes in mammals, together with various splice variants displaying tissue-specific expression patterns and flexible hetero-polymeric higher-order assembly achieve an unfathomable complexity superior to the other cytoskeletal components. Even though the initial studies in the septin field was restricted to their evolutionarily conserved role in cell division, strong expression of septins in the non-dividing cells of the brain generated great interest in understanding their role in neuronal morphogenesis and other aspects of cellular function. On one hand, recent developments indicate complex non-canonical roles for septins in diverse processes ranging from neuronal development to immune response and calcium signaling. On the other hand several lines of data including those from knockout models question the universal role for septins in animal cell cytokinesis. Mammalian hematopoietic cells seem to proliferate and efficiently undergo cytokinesis in the absence of pivotal septin proteins in a context-dependent manner. The lack of septin-dependence of hematopoiesis also opens the possibility of safely targeting septin-dependent cytokinesis for solid-tumor therapy. Thus the septin field is perfectly poised with novel roles for septins being discovered and the basic understanding on septin assembly and its canonical functions constantly revisited. The objective of this research topic was to provide an exclusive platform for discussing these rapid advances in the septin field. With a mixture of reviews and research articles encompassing diverse areas of septin research, ranging from the humble yeast model to human cancer, this ebook will be an interesting reading material for both experts as well as new comers to the septin field.
Septins
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-07-26
Septins written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-26 with Science categories.
Septins provides established septin and molecular and developmental biologists and researchers new to the field with proven, state-of-art techniques and relevant historical background and theory to aid efficient design and effective implementation of experimental methodologies. Topics include the purification of septin proteins from diverse systems, their visualization in live cells, and their analysis by a variety of cutting-edge microscopy approaches. - Provides the latest information on septins - Includes both established and new technologies - Brings together specialists from the field who contribute their expertise
The Cytoskeleton In Health And Disease
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Author : Heide Schatten
language : en
Publisher: Springer
Release Date : 2015-08-21
The Cytoskeleton In Health And Disease written by Heide Schatten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-21 with Science categories.
This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.
New Drug Targets For Proteotoxicity In Cardiometabolic Diseases
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Author : Jun Ren
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-02
New Drug Targets For Proteotoxicity In Cardiometabolic Diseases written by Jun Ren and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-02 with Science categories.
Immunity To Listeria Monocytogenes
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-01-25
Immunity To Listeria Monocytogenes written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-25 with Medical categories.
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Fertilization And Early Embryogenesis From Research To Clinical Practice
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Author : Martin Anger
language : en
Publisher: Frontiers Media SA
Release Date : 2025-01-23
Fertilization And Early Embryogenesis From Research To Clinical Practice written by Martin Anger and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-23 with Science categories.
Early embryo development in mammals begins with the recognition and fusion of gametes of both sexes, followed by a series of mitotic cell divisions. The gamete fusion results in the formation of totipotent cells, which are capable of developing into three basic cell lineages in mammals. These include the trophoblast, surrounding the embryo and facilitating communication with the mother, the epiblast which develops into the fetus, and the primitive endoderm which forms the yolk sac. Until implantation, the embryos undergo remarkable changes, including histone modifications, chromatin remodeling, epigenetic modifications of chromatin, the onset of transcription from the embryonic genome, and the first differentiation to the formation of the trilaminar disc, containing all primary cell lineages required for the formation of fetal tissues and organs. Remarkably, some of the most complex events of early development, such as fertilization, are achieved during complete transcriptional silencing. Another unique feature is how fast the development proceeds. In humans, reaching the stage of early gastrulation takes approximately two weeks.
New And Future Developments In Microbial Biotechnology And Bioengineering
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Author : Joginder Singh Panwar
language : en
Publisher: Elsevier
Release Date : 2020-09-21
New And Future Developments In Microbial Biotechnology And Bioengineering written by Joginder Singh Panwar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-21 with Technology & Engineering categories.
New and Future Developments in Microbial Biotechnology and Bioengineering presents an account of recent developments and applied aspects of fungi and its metabolites for human welfare. The fungi and its metabolites are employed in diverse fields of agri-food, biochemistry, chemical engineering, diagnostics, pharmaceuticals and medical device development. The book contains chapters by the eminent researchers working with fungi and fungal metabolites who explain their importance and potential in manifold prospects. The book includes a description of various fungal metabolites and their chemistry and biotechnology. - Highlights the latest developments surrounding the utilization of fungi and fungal metabolites - Overviews applied aspects of fungi and their metabolites for human welfare - Details the usage of fungi and their metabolites in diverse fields - Identifies the importance and potential of fungi and fungal metabolites in manifold prospects - Illustrates recent trends in fungal metabolite research using elaborate, expressive tables and figures with concise information
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher: Garland Science
Release Date : 2017-08-07
Molecular Biology Of The Cell written by Bruce Alberts and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-07 with Science categories.
As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
Cancer Genes Volume 2
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Author : Satish Ramalingam
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-08-17
Cancer Genes Volume 2 written by Satish Ramalingam and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-17 with Medical categories.
Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease. The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes13-23 (volume 2). A key feature of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer-causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.