Emerging Strategies In Neuroprotection

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Emerging Strategies In Neuroprotection
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Author : Manangos
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21
Emerging Strategies In Neuroprotection written by Manangos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Social Science categories.
SOLOMON H. SNYDER Receptor Research Reaches Neurology: Relevance to Neurodegenerative Diseases and Stroke President George Bush has heralded the 1990s as the decade of the brain, based largely on the rapid escalation of advances in the molecular neuro sciences and the likelihood that these will bear therapeutic fruit before the turn of the century. There is little doubt that the 1970s and 1980s have witnessed more remarkable advances in the molecular neurosciences than all of the preceding hundred years. Identification of receptor sites for drugs and neurotransmitters along with simple, sensitive, and specific means of monitoring them has made it possible to elucidate the mechanism of action for many known drugs and to identify new chemical entities as potential therapeutic agents. At the same time, the numbers of distinct neurotrans mitters have multiplied. Prior to 1970 only the biogenic amines were well accepted as transmitters. The early 1970s witnessed the gradual acceptance ofamino acids as major excitatory and inhibitory neurotransmitters. Identification of opiate receptors and the subsequent identification of the enkephalins as their endogenous ligands led to an appreciation of peptides as putative transmitters and the accumulation of as many as a hundred neuropeptides by the decade's end. In the 1980s the revolutions of molecular biology have been applied aggressively to the neurosciences with molecular cloning for neuropeptide precursors, many important neurochemical en zymes, and receptors for numerous transmitters.
Neuroprotection In Alzheimer S Disease
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Author : Illana Gozes
language : en
Publisher: Academic Press
Release Date : 2017-01-18
Neuroprotection In Alzheimer S Disease written by Illana Gozes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-18 with Psychology categories.
Neuroprotection in Alzheimer's Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer's disease will pave the path to better disease management and novel therapeutics.
Molecular Basis And Emerging Strategies For Anti Aging Interventions
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Author : Syed Ibrahim Rizvi
language : en
Publisher: Springer
Release Date : 2018-11-02
Molecular Basis And Emerging Strategies For Anti Aging Interventions written by Syed Ibrahim Rizvi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Medical categories.
This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.
Remote Ischemic Conditioning Pre Per And Post As An Emerging Strategy Of Neuroprotection In Ischemic Stroke
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Author : Francisco Purroy
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-18
Remote Ischemic Conditioning Pre Per And Post As An Emerging Strategy Of Neuroprotection In Ischemic Stroke written by Francisco Purroy and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-18 with Medical categories.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1992-10
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10 with Medicine categories.
Advances And Technical Standards In Neurosurgery
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Author : L. Symon
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Advances And Technical Standards In Neurosurgery written by L. Symon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo Krayenbiihl. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this serIes. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by spe cialists in the given fields and constitute the first part of each volume.
New Strategies In Stroke Intervention
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Author : Lucio Annunziato
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
New Strategies In Stroke Intervention written by Lucio Annunziato and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for curing stroke is far less understood than for many other normal and pathological conditions. New Strategies in Stroke Intervention: Ionic Channels, Pumps, and Transporters, analyzes the roles played by targets in stroke development and the potential action of drugs modulating these proteins. This book provides a groundbreaking review of these ionic channels, pumps, and transporters as regulators of neuronal ionic homeostasis, providing a better understanding of ischemic brain disorders and the new pharmacological avenues for a cure.
The Handbook Of Neuroprotection
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Author : Kewal K. Jain
language : en
Publisher: Springer
Release Date : 2019-05-15
The Handbook Of Neuroprotection written by Kewal K. Jain and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-15 with Medical categories.
This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system. In-depth and authoritative, The Handbook of Neuroprotection, Second Edition features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.
Neuroprotective Agents And Cerebral Ischaemia
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Author :
language : en
Publisher: Academic Press
Release Date : 1996-11-26
Neuroprotective Agents And Cerebral Ischaemia written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-11-26 with Medical categories.
Since 1959, International Review of Neurobiology has been a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes. Stroke is the third major cause of death in the western world, and recent data provide hope that treatments may soon be available. Written by world experts on the mechanisms involved in neurodegeneration, Neuroprotective Agents and Cerebral Ischaemia presents an up-to-date review of current research and developing therapies. This book is essential reading for all clinicians and researchers searching for neuroprotective drugs. - Describes the mechanisms involved in cell death and the biochemical changes occurring during an ischaemic episode - Presents the different factors affecting the neurodegenerative process and how compounds acting on these systems may lead to novel neuroprotective agents - Reviews in vitro and in vivo models of stroke and the activity of putative neuroprotective drugs - Discusses the application of preclinical data to formulate approaches to a clinical problem - Provides detailed reviews of both completed clinical trials and those currently underway
Nanoneuroscience And Nanoneuropharmacology
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Author : Hari S. Sharma
language : en
Publisher: Elsevier
Release Date : 2009-12-03
Nanoneuroscience And Nanoneuropharmacology written by Hari S. Sharma and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-03 with Science categories.
This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.