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Engineering Genetic Circuits

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Engineering Genetic Circuits

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Author : Chris J. Myers
language : en
Publisher: CRC Press
Release Date : 2018-09-10

Engineering Genetic Circuits written by Chris J. Myers and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-10 with Combinational circuits categories.

An Introduction to Systems Bioengineering Takes a Clear and Systematic Engineering Approach to Systems Biology Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to guide the design of new circuits. After reviewing the basic molecular biology and biochemistry principles needed to understand genetic circuits, the book describes modern experimental techniques and methods for discovering genetic circuit models from the data generated by experiments. The next four chapters present state-of-the-art methods for analyzing these genetic circuit models. The final chapter explores how researchers are beginning to use analytical methods to design synthetic genetic circuits. This text clearly shows how the success of systems biology depends on collaborations between engineers and biologists. From biomolecular observations to mathematical models to circuit design, it provides essential information on genetic circuits and engineering techniques that can be used to study biological systems.

Engineering Genetic Circuits

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Author : Chris J. Myers
language : en
Publisher: CRC Press
Release Date : 2016-04-19

This text presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to design new circuits. The author reviews basic molecular biology and biochemistry principles, covers several methods for modeling and analyzing genetic circuits, and uses phage lambda as an example throughout to help illustrate the methods. He also explores the emerging area of synthetic biology. iBioSim software, lecture slides, and a password-protected solutions manual are available on the author's website.

The Science And Applications Of Synthetic And Systems Biology

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-12-30

The Science And Applications Of Synthetic And Systems Biology written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-30 with Science categories.

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

An Introduction To Genetic Engineering

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Author : Desmond S. T. Nicholl
language : en
Publisher: Cambridge University Press
Release Date : 2002-02-07

An Introduction To Genetic Engineering written by Desmond S. T. Nicholl and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-07 with Medical categories.

Zero To Genetic Engineering Hero

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Author : Justin Pahara
language : en
Publisher: Maker Media, Inc.
Release Date : 2021-08-19

Zero To Genetic Engineering Hero written by Justin Pahara and has been published by Maker Media, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Science categories.

Zero to Genetic Engineering Hero is made to provide you with a first glimpse of the inner-workings of a cell. It further focuses on skill-building for genetic engineering and the Biology-as-a-Technology mindset (BAAT). This book is designed and written for hands-on learners who have little knowledge of biology or genetic engineering. This book focuses on the reader mastering the necessary skills of genetic engineering while learning about cells and how they function. The goal of this book is to take you from no prior biology and genetic engineering knowledge toward a basic understanding of how a cell functions, and how they are engineered, all while building the skills needed to do so.

Engineering Tuneable Gene Circuits In Yeast

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Author : Stephen Checkley
language : en
Publisher: GRIN Verlag
Release Date : 2015-09-14

Engineering Tuneable Gene Circuits In Yeast written by Stephen Checkley and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-14 with Science categories.

Doctoral Thesis / Dissertation from the year 2011 in the subject Chemistry - Bio-chemistry, grade: pass, University of Manchester (Manchester Institute of Biotechnology), course: Systems biology doctoral training program -synthetic biology, language: English, abstract: Synthetic biology is an emergent field incorporating aspects of computer science, molecular biology-based methodologies in a systems biology context, taking naturally occurring cellular systems, pathways, and molecules, and selectively engineering them for the generation of novel or beneficial synthetic behaviour. This study described the construction of a novel synthetic gene circuit with interchangeable gene expression components enabling the investigation of tuning circuits for optimal signal to noise ratio. The circuit utilises the inducible downstream transcriptional activation properties of the pheromone-response pathway in the budding yeast Saccharomyces cerevisiae as the basis for initiation.

Advances In Synthetic Biology

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Author : Vijai Singh
language : en
Publisher: Springer
Release Date : 2021-08-26

Advances In Synthetic Biology written by Vijai Singh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-26 with Science categories.

This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.

Designing Human Practices

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Author : Paul Rabinow
language : en
Publisher: University of Chicago Press
Release Date : 2012-05-21

Designing Human Practices written by Paul Rabinow and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-21 with Science categories.

In 2006 anthropologists Paul Rabinow and Gaymon Bennett set out to rethink the role that human sciences play in biological research, creating the Human Practices division of the Synthetic Biology Engineering Research Center—a facility established to create design standards for the engineering of new enzymes, genetic circuits, cells, and other biological entities—to formulate a new approach to the ethical, security, and philosophical considerations of controversial biological work. They sought not simply to act as watchdogs but to integrate the biosciences with their own discipline in a more fundamentally interdependent way, inventing a new, dynamic, and experimental anthropology that they could bring to bear on the center’s biological research. Designing Human Practices is a detailed account of this anthropological experiment and, ultimately, its rejection. It provides new insights into the possibilities and limitations of collaboration, and diagnoses the micro-politics which effectively constrained the potential for mutual scientific flourishing. Synthesizing multiple disciplines, including biology, genetics, anthropology, and philosophy, alongside a thorough examination of funding entities such as the National Science Foundation, Designing Human Practices pushes the social study of science into new and provocative territory, utilizing a real-world experience as a springboard for timely reflections on how the human and life sciences can and should transform each other.

The Lac Operon

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Author : Benno Müller-Hill
language : en
Publisher: Walter de Gruyter
Release Date : 2011-05-12

The Lac Operon written by Benno Müller-Hill and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-12 with Science categories.

No detailed description available for "The lac Operon".

Genetic Programming Iv

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Author : John R. Koza
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-03-21

Genetic Programming Iv written by John R. Koza and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-21 with Computers categories.

Genetic Programming IV: Routine Human-Competitive Machine Intelligence presents the application of GP to a wide variety of problems involving automated synthesis of controllers, circuits, antennas, genetic networks, and metabolic pathways. The book describes fifteen instances where GP has created an entity that either infringes or duplicates the functionality of a previously patented 20th-century invention, six instances where it has done the same with respect to post-2000 patented inventions, two instances where GP has created a patentable new invention, and thirteen other human-competitive results. The book additionally establishes: GP now delivers routine human-competitive machine intelligence GP is an automated invention machine GP can create general solutions to problems in the form of parameterized topologies GP has delivered qualitatively more substantial results in synchrony with the relentless iteration of Moore's Law

Engineering Genetic Circuits

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