Epigenetic Regulation In Cancer Immunity


Epigenetic Regulation In Cancer Immunity
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Epigenetic Regulation In Cancer Immunity


Epigenetic Regulation In Cancer Immunity
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Author : Bo Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-21

Epigenetic Regulation In Cancer Immunity written by Bo Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-21 with Medical categories.




Epigenetic Regulation Of Cancer Part C


Epigenetic Regulation Of Cancer Part C
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Author :
language : en
Publisher: Academic Press
Release Date : 2024-10-01

Epigenetic Regulation Of Cancer Part C written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-01 with Science categories.


Epigenetic Regulation of Cancer, Part C, in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic control of cell signaling in cancer stem cells, Genetic and epigenetic features of neuroendocrine prostate cancer and their emerging applications, Epigenetic regulation in pancreatic cancer, Epigenome Editing in Cancer: Advances and Challenges for Potential Therapeutic Options, Inhibition of epigenetic mechanisms in cancer, and Epigenetics as a determinant of radiation response in cancer.



Metabolism And Epigenetic Regulation Implications In Cancer


Metabolism And Epigenetic Regulation Implications In Cancer
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Author : Tapas Kumar Kundu
language : en
Publisher: Springer Nature
Release Date : 2022-10-27

Metabolism And Epigenetic Regulation Implications In Cancer written by Tapas Kumar Kundu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-27 with Science categories.


Metabolic programs of individuals are key determinants for disease susceptibility and immune response. This book, edited by experts in the field, summarizes epigenetic signaling pathways that regulate metabolic programs associated with cancer and cancer-related secondary diseases. The first part of the book highlights key metabolic pathways that are implicated in cancer and provides a comprehensive overview on the carbohydrate, protein, lipid, amino- and nucleic acid metabolic pathways that are deregulated in cancer. Special attention is paid to the altered tumor micro-environment that is influenced by the metabolic milieu. Furthermore, the fundamental relationship between the cellular metabolic environment and cell death-mediated autophagy is discussed. The second part of the book covers our understanding of the fundamental epigenetic regulations that are implicated in controlling the metabolic programs in cancer cells. Many aspects of epigenetic regulation of non-coding RNAs as well as DNA/RNA methylation, which influencing metabolic homeostasis in cancer, are discussed in detail. Special emphasis is placed on the epigenetic regulation of the amino acid, glucose/carbohydrate metabolism and epigenetic regulation during hypoxia and its connection to cancer. Last but not least, the third part of the book covers small molecule modulators of histone modifying enzymes, which can be used as therapeutic tools. The readers learn about the cross-talk between epigenetics and immunometabolims, as well as the epigenetic regulation of oncometabolites to combat cancer. Given its scope, the book will appeal to a broad readership interested in epigenetic, cancer and metabolic research.



Genetic And Epigenetic Control On Immune Responses Regulating Molecules In Cancer Development Progression And Treatment


Genetic And Epigenetic Control On Immune Responses Regulating Molecules In Cancer Development Progression And Treatment
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Author : Katherine Chiappinelli
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-30

Genetic And Epigenetic Control On Immune Responses Regulating Molecules In Cancer Development Progression And Treatment written by Katherine Chiappinelli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Medical categories.




Molecular Basis Of Epigenetic Regulation In Cancer Therapies


Molecular Basis Of Epigenetic Regulation In Cancer Therapies
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Author : Ángeles Carlos Reyes
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-10

Molecular Basis Of Epigenetic Regulation In Cancer Therapies written by Ángeles Carlos Reyes and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-10 with Science categories.




Epigenetic Regulation Of Cancer Part B


Epigenetic Regulation Of Cancer Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-04

Epigenetic Regulation Of Cancer Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04 with Science categories.


Epigenetic Regulation of Cancer, Part B, Volume 383 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic control of cell signaling in cancer stem cells, Genetic and epigenetic features of neuroendocrine prostate cancer and their emerging applications, Epigenetic regulation in pancreatic cancer, Epigenome Editing in Cancer: Advances and Challenges for Potential Therapeutic Options, Inhibition of epigenetic mechanisms in cancer, and Epigenetics as a determinant of radiation response in cancer.



Epigenetic Regulation And Tumor Immunotherapy


Epigenetic Regulation And Tumor Immunotherapy
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Author : Mingzhu Yin
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-27

Epigenetic Regulation And Tumor Immunotherapy written by Mingzhu Yin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-27 with Medical categories.




Epigenetic Regulation Of Cancer In Response To Chemotherapy


Epigenetic Regulation Of Cancer In Response To Chemotherapy
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-03-27

Epigenetic Regulation Of Cancer In Response To Chemotherapy written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-27 with Medical categories.


Epigenetic Regulation of Cancer in Response to Chemotherapy, Volume 158 of the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting chapters on timely topics, including Epigenetically Programmed Resistance to Chemotherapy and Promotion of Immune Evasion in Cancer, A Role for the Epigenome in Cancer Cell Drug Tolerance, Histone Methylation and X Chromosomal Genes in Metastasis of Breast Cancer, Targeting Epigenetic Regulation Using Small Molecule Inhibitors, Histone Deacetylase Inhibitors as Sanguine Epigenetic Therapeutics against Pugnacious Lung Cancer, From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia), and more. Additional chapters cover Predictive Models of Chemoresistance Generated by Crunching the Public Drug Screen, Epigenomic and Genomic Profiling Datasets via Regression-, Machine Learning, and Knowledge-Based Methods, Probing on the Mechanisms of lncRNAs on Cancer Drug Resistance, Drug Tolerant Persister Cells in Cancer: Current Knowledge and Therapeutic Perspectives, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Cancer Research series Includes the latest information on the Epigenetic Regulation of Cancer in Response to Chemotherapy



Epigenetic Regulation And Non Histone Post Translational Modification In Cancer


Epigenetic Regulation And Non Histone Post Translational Modification In Cancer
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Author : Yan Gong
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-03

Epigenetic Regulation And Non Histone Post Translational Modification In Cancer written by Yan Gong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-03 with Science categories.




Epigenetics And Cancer


Epigenetics And Cancer
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Author : Fazlul H. Sarkar
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-29

Epigenetics And Cancer written by Fazlul H. Sarkar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Medical categories.


Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role of epigenetic deregulation of microRNAs (miRNAs) and their target mRNAs along with epigenetic deregulation of mRNAs. This book also illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in modulating the epigenetic reprogramming of miRNAs and mRNAs for the prevention and/or treatment of human malignancies. It is well known that genetic aberrations, especially inherited through parents (somatic genetic alterations) contribute to the development of less than 10% of all cancer yet epigenetic alterations in genes especially through selective methylation and acetylation appears to be responsible for the development and progression of the vast majority of all cancers. Therefore, understanding the role of epigenetics in the regulation of genes especially through deregulated expression of miRNAs as presented in this book will allow scientists to devise targeted therapeutic strategies for re-expression of the lost genes or down-regulate the genes that are over-expressed in order to eradicate cancer. It is hoped that targeting epigenetics will not only target cancer cells but it will also target the tumor microenvironment (more like the entire tumor environment such as the entire host) for achieving better treatment outcomes for patients diagnosed with cancer which will lead to achieve the long-term objective for complete eradication of cancer. This book contains fifteen chapters which begins with the concept of systems and network biology for investigating the epigenetics of cancer followed by a series of articles on the role of miRNAs and their target genes in the biology of pancreatic cancer and other cancers such as breast, kidney, prostate and and colon. Since it is becoming increasingly clear that cancer stem cells (CSCs) are important in the development and progression of cancer, and CSCs are important in therapeutic resistance, treatment failure and tumor recurrence, thus the importance of CSCs and epigenetics has been highlighted by a very timely article on epigenetic variations of stem cell markers in cancer including miRNAs. Moreover, just targeting heterogeneous cancer cell populations may not be optimal to eradicate tumors and for which one must take a holistic approach for developing drugs that could also target the tumor microenvironment and tumor dormancy that are regulated through epigenetics. Keeping abreast with this thought process the concluding chapter provides a concept towards curative cancer therapy with maspin, which could be a unique window of opportunity to target tumor dormancy. Therefore, it suggest that targeting the tumor dormancy and the tumor microenvironment using novel therapeutics specifically by targeting epigenetics would become the future of medicine.