Epigenetic Regulation In Cardiovascular Diseases
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Epigenetic Regulation In Cardiovascular Diseases
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Author : Zhihua Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-16
Epigenetic Regulation In Cardiovascular Diseases written by Zhihua Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-16 with Science categories.
Examining Genetic And Epigenetic Regulation In Cardiovascular Development Regeneration And Disease
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Author : Eltyeb Abdelwahid
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-06
Examining Genetic And Epigenetic Regulation In Cardiovascular Development Regeneration And Disease written by Eltyeb Abdelwahid and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-06 with Medical categories.
Epigenetics In Cardiac Disease
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Author : Johannes Backs
language : en
Publisher: Springer
Release Date : 2016-11-21
Epigenetics In Cardiac Disease written by Johannes Backs and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-21 with Medical categories.
This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
Epigenetics In Cardiovascular Disease
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Author : Yvan Devaux
language : en
Publisher: Academic Press
Release Date : 2021-03-06
Epigenetics In Cardiovascular Disease written by Yvan Devaux and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-06 with Medical categories.
Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies. More than thirty international experts provide an (i) overview of the epigenetics mechanisms and their contribution to cardiovascular disease development, (i) high-throughput methods for RNA profiling including single-cell RNA-seq, (iii) the role of nucleic acid methylation in cardiovascular disease development, (iv) epigenetic actors as biomarkers and drug targets, (v) and the potential of epigenetics to advance personalized medicine. Here, readers will discover strategies to combat research challenges, improve quality of their epigenetic research and reproducibility of their findings. Additionally, discussion of assay and drug development for personalized healthcare pave the way for a new era of understanding in cardiovascular disease. Offers a thorough overview of role of epigenetics mechanisms in cardiovascular disease Includes guidance to improve research plans, experimental protocols design, quality and reproducibility of results in new epigenetics research Explores biomarkers and drug targets of therapeutic potential to advance personalized healthcare Features chapter contributions from a wide range of international researchers in the field
Epigenetic And Genetic Mechanisms Underlying Cardiovascular Diseases And Neurodevelopmental Disorders
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Author : Lingshan Gou
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-11
Epigenetic And Genetic Mechanisms Underlying Cardiovascular Diseases And Neurodevelopmental Disorders written by Lingshan Gou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-11 with Medical categories.
Cardiovascular disease (CVD) and neurodevelopmental disorders (NDD) are both common diseases seriously affecting human health. CVD refers to a broad range of disorders including diseases affecting the vasculature, the myocardium, the heart’s electrical circuit, and congenital heart disease. NDDs are conditions affecting brain development and function, mainly characterized by impairments of cognition, communication, and motor skills. Although the heart and brain develop in spatially distinct regions, they share similar genetic factors and molecular pathways which are crucial for a precise developmental trajectory. Actually, congenital CVD survivors are at a higher risk of NDD, and whole-exome sequencing revealed a significant overlap between high-risk congenital CVD and NDD genetic variants. For CVD and NDD, the clinical presentations are heterogeneous, and the etiologies are complex. Elucidating the potential pathogenic mechanisms is good for unveiling the pathophysiology and finding the novel therapeutic target.
Non Coding Rnas In Cardiovascular Diseases
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Author : Junjie Xiao
language : en
Publisher: Springer Nature
Release Date : 2020-04-13
Non Coding Rnas In Cardiovascular Diseases written by Junjie Xiao and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-13 with Science categories.
This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects. It is particularly useful for researchers and students in the field of non-coding RNA and cardiovascular biology, as well as for cardiologists, pharmacologists and physiologists.
Epigenetics In Human Disease
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Author : Trygve O Tollefsbol
language : en
Publisher: Elsevier
Release Date : 2023-10-09
Epigenetics In Human Disease written by Trygve O Tollefsbol and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-09 with Medical categories.
Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, this Third Edition discusses topics of current interest in epigenetic disease research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, microRNA in cancer, epigenetic approaches to control obesity, epigenetics and airway disease, and epigenetics in cardiovascular disease. Further sections explore online epigenetic tools and datasets; early-life programming of epigenetics in age-related diseases; the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies. In addition, each chapter now includes chapter summaries, definitions, and vibrant imagery and figures to reinforce understanding, as well as step-by-step methods and disease research case studies. Includes contributions from leading international investigators involved in translational epigenetic research and therapeutic applications Integrates methods and applications with fundamental chapters on epigenetics in human disease, along with an evaluation of recent clinical breakthroughs Presents side-by-side coverage of the basis of epigenetic diseases and treatment pathways Each chapter updated to include summaries, definitions, and vibrant imagery and figures to reinforce understanding Features step-by-step methods and disease research case studies to put book concepts into practice
Computational Epigenetics And Diseases
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-02-06
Computational Epigenetics And Diseases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with Business & Economics categories.
Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases
Epigenetics Brain And Behavior
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Author : Paolo Sassone Corsi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-19
Epigenetics Brain And Behavior written by Paolo Sassone Corsi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-19 with Medical categories.
Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molcular mechanisms implicated in epigentic control and how these may operte in concert. It will be critical to unravel how specifity is achieved. The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.
Nutrition Epigenetics And Health
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Author : Burdge Graham
language : en
Publisher: World Scientific
Release Date : 2016-10-07
Nutrition Epigenetics And Health written by Burdge Graham and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-07 with Medical categories.
Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.