Evolution By Tumor Neofunctionalization
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Evolution By Tumor Neofunctionalization
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Author : Andrei P. Kozlov
language : en
Publisher: Academic Press
Release Date : 2014-02-15
Evolution By Tumor Neofunctionalization written by Andrei P. Kozlov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-15 with Science categories.
Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. Covers the role that tumors might play in evolution. Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more
Ecology And Evolution Of Cancer
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Author : Beata Ujvari
language : en
Publisher: Academic Press
Release Date : 2017-02-08
Ecology And Evolution Of Cancer written by Beata Ujvari and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-08 with Medical categories.
Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies
Cancer Selection
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Author : James Graham
language : en
Publisher: Aculeus Pr
Release Date : 1992
Cancer Selection written by James Graham and has been published by Aculeus Pr this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.
Conventional evolutionary theory cannot explain the existence of humans & other complex animals; another mechanism is needed, says James Graham, & it is none other than cancer. This radical theory, already published in a science journal, is aimed at amateurs & professionals. "I think I agree with him... a good idea," John W. Galloway, Nature. "Intriguing...resolves many outstanding problems," SciTech Book News. Literary reviewers like it too: "absorbing...provocative." The Small Press Book Review. "fascinating...sheer intellectual virtuosity." West Coast Review of Books. "distinguished." The Book Reader. Order from: James Graham, PO Box 142, Lexington Virginia 24450 telephone 540 464 4554. Also available from Amazon.com, Barnes & Noble and other retailers.
Understanding Human Anatomy Through Evolution Second Edition
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Author : Bruce D. Olsen
language : en
Publisher: Lulu.com
Release Date : 2009-05-09
Understanding Human Anatomy Through Evolution Second Edition written by Bruce D. Olsen and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-09 with Science categories.
Mr. Olsen wrote this book on human anatomy from an evolutionary perspective for college undergraduates with no previous college-level math or science. It contains an introduction to the nature of science and biological evolution in addition to a clear and comprehensive description of basic human anatomy. With over one hundred references, a detailed index, and more than 40 black-and-white illustrations and tables, this book is the perfect supplement to a standard anatomical atlas or textbook with color illustrations.
Macroevolution
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Author : Emanuele Serrelli
language : en
Publisher: Springer
Release Date : 2015-02-13
Macroevolution written by Emanuele Serrelli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-13 with Science categories.
This book is divided in two parts, the first of which shows how, beyond paleontology and systematics, macroevolutionary theories apply key insights from ecology and biogeography, developmental biology, biophysics, molecular phylogenetics and even the sociocultural sciences to explain evolution in deep time. In the second part, the phenomenon of macroevolution is examined with the help of real life-history case studies on the evolution of eukaryotic sex, the formation of anatomical form and body-plans, extinction and speciation events of marine invertebrates, hominin evolution and species conservation ethics. The book brings together leading experts, who explain pivotal concepts such as Punctuated Equilibria, Stasis, Developmental Constraints, Adaptive Radiations, Habitat Tracking, Turnovers, (Mass) Extinctions, Species Sorting, Major Transitions, Trends and Hierarchies – key premises that allow macroevolutionary epistemic frameworks to transcend microevolutionary theories that focus on genetic variation, selection, migration and fitness. Along the way, the contributing authors review ongoing debates and current scientific challenges; detail new and fascinating scientific tools and techniques that allow us to cross the classic borders between disciplines; demonstrate how their theories make it possible to extend the Modern Synthesis; present guidelines on how the macroevolutionary field could be further developed; and provide a rich view of just how it was that life evolved across time and space. In short, this book is a must-read for active scholars and because the technical aspects are fully explained, it is also accessible for non-specialists. Understanding evolution requires a solid grasp of above-population phenomena. Species are real biological individuals and abiotic factors impact the future course of evolution. Beyond observation, when the explanation of macroevolution is the goal, we need both evidence and theory that enable us to explain and interpret how life evolves at the grand scale.
Homology Genes And Evolutionary Innovation
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Author : Günter P. Wagner
language : en
Publisher: Princeton University Press
Release Date : 2018-07-10
Homology Genes And Evolutionary Innovation written by Günter P. Wagner and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-10 with Science categories.
A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.
Oxford Textbook Of Cancer Biology
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Author : Francesco Pezzella
language : en
Publisher: Oxford University Press
Release Date : 2019-05-02
Oxford Textbook Of Cancer Biology written by Francesco Pezzella and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-02 with Medical categories.
The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.
Progress In Botany Vol 81
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Author : Francisco M. Cánovas
language : en
Publisher: Springer Nature
Release Date : 2020-01-23
Progress In Botany Vol 81 written by Francisco M. Cánovas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-23 with Science categories.
With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.
Lectures On General Pathology
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Author : Julius Cohnheim
language : en
Publisher:
Release Date : 1889
Lectures On General Pathology written by Julius Cohnheim and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1889 with Animal heat categories.
Interactive Web Based Data Visualization With R Plotly And Shiny
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Author : Carson Sievert
language : en
Publisher: CRC Press
Release Date : 2020-01-30
Interactive Web Based Data Visualization With R Plotly And Shiny written by Carson Sievert and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-30 with Business & Economics categories.
The richly illustrated Interactive Web-Based Data Visualization with R, plotly, and shiny focuses on the process of programming interactive web graphics for multidimensional data analysis. It is written for the data analyst who wants to leverage the capabilities of interactive web graphics without having to learn web programming. Through many R code examples, you will learn how to tap the extensive functionality of these tools to enhance the presentation and exploration of data. By mastering these concepts and tools, you will impress your colleagues with your ability to quickly generate more informative, engaging, and reproducible interactive graphics using free and open source software that you can share over email, export to pdf, and more. Key Features: Convert static ggplot2 graphics to an interactive web-based form Link, animate, and arrange multiple plots in standalone HTML from R Embed, modify, and respond to plotly graphics in a shiny app Learn best practices for visualizing continuous, discrete, and multivariate data Learn numerous ways to visualize geo-spatial data This book makes heavy use of plotly for graphical rendering, but you will also learn about other R packages that support different phases of a data science workflow, such as tidyr, dplyr, and tidyverse. Along the way, you will gain insight into best practices for visualization of high-dimensional data, statistical graphics, and graphical perception. The printed book is complemented by an interactive website where readers can view movies demonstrating the examples and interact with graphics.