Examining The State Of The Science Of Mammalian Embryo Model Systems


Examining The State Of The Science Of Mammalian Embryo Model Systems
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Examining The State Of The Science Of Mammalian Embryo Model Systems


Examining The State Of The Science Of Mammalian Embryo Model Systems
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2020-07-31

Examining The State Of The Science Of Mammalian Embryo Model Systems written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-31 with Medical categories.


Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.



Stem Cells And The Future Of Regenerative Medicine


Stem Cells And The Future Of Regenerative Medicine
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2002-01-25

Stem Cells And The Future Of Regenerative Medicine written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-01-25 with Science categories.


Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.



Scientific Frontiers In Developmental Toxicology And Risk Assessment


Scientific Frontiers In Developmental Toxicology And Risk Assessment
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-12-21

Scientific Frontiers In Developmental Toxicology And Risk Assessment written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-21 with Nature categories.


Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.



Early Mammalian Development


Early Mammalian Development
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Author : Matthew H. Kaufman
language : en
Publisher: CUP Archive
Release Date : 1983-10-06

Early Mammalian Development written by Matthew H. Kaufman and has been published by CUP Archive this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-10-06 with Nature categories.




Human Trophoblast


Human Trophoblast
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Author : Arthur Tremain Hertig
language : en
Publisher:
Release Date : 1968

Human Trophoblast written by Arthur Tremain Hertig and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Medical categories.




Scientific And Medical Aspects Of Human Reproductive Cloning


Scientific And Medical Aspects Of Human Reproductive Cloning
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2002-06-17

Scientific And Medical Aspects Of Human Reproductive Cloning written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-17 with Science categories.


Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.



Mammalian Preimplantation Development


Mammalian Preimplantation Development
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-07-26

Mammalian Preimplantation Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-26 with Science categories.


Mammalian Preimplantation Development, the latest volume in the Current Topics in Developmental Biology series covers mammalian preimplantation development, and includes contributions from an international board of authors. The book's chapters provide a comprehensive set of reviews covering such topics as cell proliferation, cell differentiation, and biological significance. Covers the area of mammalian preimplantation development Includes contributions from an International board of authors Provides a comprehensive set of reviews covering such topics as cell proliferation, cell differentiation, and biological significance



Mammalian Development


Mammalian Development
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Author : Patrick P. L. Tam
language : en
Publisher:
Release Date : 2013

Mammalian Development written by Patrick P. L. Tam and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Science categories.


"A subject collection from Cold Spring Harbor perspectives in biology."



Differentiation Of Embryonic Stem Cells


Differentiation Of Embryonic Stem Cells
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Author :
language : en
Publisher: Elsevier
Release Date : 2003-12-18

Differentiation Of Embryonic Stem Cells written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-18 with Science categories.


This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery. * Early commitment steps and generation of chimeric mice * Differentiation to mesoderm derivatives * Gene discovery by manipulation of mouse embryonic stem cells



Exploring The Biological Contributions To Human Health


Exploring The Biological Contributions To Human Health
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-07-02

Exploring The Biological Contributions To Human Health written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-02 with Medical categories.


It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.