Experimental Colon Carcinogenesis


Experimental Colon Carcinogenesis
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Experimental Colon Carcinogenesis


Experimental Colon Carcinogenesis
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Author : Herman Autrup
language : en
Publisher: CRC Press
Release Date : 2019-06-04

Experimental Colon Carcinogenesis written by Herman Autrup and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.


First Published in 1983, Experimental Colon Carcinogenesis is a helpful guide through the development of cancer cells and the circumstances in which they develop. This book works best as a reference to all factors that must be considered with colorectal cancer and is useful for students of medicine or practitioners in their respective fields.



Colorectal Cancer


Colorectal Cancer
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Author : Helmut K. Seitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Colorectal Cancer written by Helmut K. Seitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The past 20 years have seen a surge of research into colorectal cancer, which is a reflection of the need to improve our methods of treating patients suffering from this increasingly common form of cancer. Greater knowledge of the basic mechanisms involved in colorectal carcinogenesis is an essential prerequisite to improvements in cancer prevention. In this volume the editors have brought together an impressive list of experts to cover the epidemiology, pathophysiology, morphology and basis for new diagnostic and therapeutic approaches to early detection and prevention. This broad scientific approach provides the reader with up-to-date review of our current state of knowl edge of colorectal carcinogenesis and indicates how this information can be used to generate more research and create new opportunities for diagnosis and treatment. This is a book of knowledge and ideas, some of them still at the stage of theoretical interest, but others with practical potential for the care of patients. I recommend it to those who have a research interest in colorectal carcinogenesis, as well as to readers who wish to know just how far medical scientists have progressed in their efforts to achieve the ideal of cancer prevention.



The Effect Of Dietary Manipulations On Experimental Colon Carcinogenesis


The Effect Of Dietary Manipulations On Experimental Colon Carcinogenesis
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Author : Judith Trudel
language : en
Publisher:
Release Date : 1985

The Effect Of Dietary Manipulations On Experimental Colon Carcinogenesis written by Judith Trudel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.




Colorectal Cancer


Colorectal Cancer
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Author : Steven M. Powell
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Colorectal Cancer written by Steven M. Powell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.


The contents of Colorectal Cancer: Methods and Protocols aim to instruct investigators in all the key genetic, cellular, and molecular biological methods of analyzing colorectal tumors. The focused techniques and assays are described in sufficient detail to allow researchers to start an experiment on colon tumors and proceed from beginning to end as if the expert in the field who has performed these studies were guiding them at the bench. Of note, most of the chapters in this volume are written by those scientists who p- neered these methods and assays in their respective fields. The chapters in Colorectal Cancer: Methods and Protocols describe “state of the art” methods to analyze colorectal tumors, ranging from gross mic- dissection of specimens to specific molecular analyses. Included are coverages of mutational assays, instability testing, immunohistochemical assays, chro- somal studies, and gene expression analyses. The goal of our volume is to facilitate the performance of colorectal tumor biological experiments by investigators at various levels of training—from graduate students and postdoctoral fellows to principal investigators who desire to advance our understanding of colon cancer development.



Colon Cancer Cells


Colon Cancer Cells
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Author : Mary Moyer
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Colon Cancer Cells written by Mary Moyer and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.


Colon Cancer Cells brings together fundamental research and clinically relevant issues in the cell biology of colon cancer. This book is composed of five parts encompassing 21 chapters that specifically describe the initiation and progression of colon cancer cells. After briefly dealing with the major issues in colorectal carcinoma, this book goes on presenting the in vitro and in vivo models of colon carcinogenesis. This topic is followed by a discussion on the history of the development and characterization of commonly used colon cancer cell lines. The following parts describe the biochemical and immunological features and hormones in the colon. These parts also consider the studies on human colon tumors xenografted into nude mice and the biology and treatment of colorectal cancer metastasis. Discussions on the application of human monoclonal antibodies to tumor detection; the expression of blood group-related carbohydrates by normal, premalignant, and malignant colonic tissues; and the correlation of antigen variability in colon carcinoma with certain diagnostic and prognostic parameters are also included in these parts. The concluding part examines various therapeutic strategies and their potential in improving patient management with advanced colon carcinoma. Researchers, clinicians, and students interested in the biology of colon cancer development and in gastrointestinal cell biology will find this book invaluable.



Colon Cancer Prevention


Colon Cancer Prevention
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Author : American Institute for Cancer Resea
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Colon Cancer Prevention written by American Institute for Cancer Resea and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The Eighth Annual Research Conference of the American Institute for Cancer Research, held in Washington, D.C., September 3-4, 1998, was on the subject "Colon Cancer Prevention: Dietary Modulation of Cellular and Molecular Mechanisms," with participants representing various disciplines interested in this area. One of the speak ers provided an appropriate quote from 17th century physician Thomas Adams: "Pre vention is better than healing because it saves the labor of being sick," which aptly describes the need for the prevention of cancer. An overview of normal and abnormal colonic development emphasized that although the typical human colon undergoes 1013 cell divisions by age 60, with the asso ciated possibilities for error, relatively few colon tumors develop. Since dietary modu lation leads to extremely small changes in colonic cells over a long period, animal models are useful to time, observe, and delineate the events associated with colon cancer. In the development colon cancer, the inactivation of the adenomatous polyposis coli (Apc) gene is one of the earliest known events. Normally Apc downregulates the cellular protein beta-catenin, but this is lost during cancer development. Beta-catenin may itself be an oncogene; it has a short half-life, but it is stabilized by binding to is more prevalent in the cell nucleus, the gene shuttles caherin. Although the Apc between the nucleus and the cytoplasm.



Gastrointestinal Tract Cancer


Gastrointestinal Tract Cancer
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Author : Martin Lipkin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Gastrointestinal Tract Cancer written by Martin Lipkin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


In observing the development of modern scientific knowledge, many indivi duals have expressed concern over the rapid growth of information in various specialized disciplines. Over 100 years ago the first Secretary of the Smith sonian Institution, and more recently Dr. Vannevar Bush while proposing the modern expansion of the National Institutes of Health, both noted prob lems that prevented the proper utilization of information by individuals in medical and related scientific fields. These observations, tagether with con comitant implications of future difficulty, are particularly pertinent to the field of oncology. The rapid evolution of the latter discipline has largely been aided by the incorporation of concepts and methods developed over a long period of time, and drawn from a wide variety of other scientific fields. The large body of discoveries that have contributed to our current understanding of neoplasia, however, cannot be viewed as being made up of equal parts. They bring to mind Claude Bernard's view "des determinismes simples et complexes" in the physiological and biochemical regulation of bod ily functions. He was able to observe that the most important and basic of physiologic processes were destined to be fewer in number than those of less fundamental and more highly specialized purpose. He understood that in the future development of medical science, sturlies of the lauer would occupy much of the time and attention of investigators, and were likely to contribute much to scientific literature.



Calcium Vitamin D And Prevention Of Colon Cancer


Calcium Vitamin D And Prevention Of Colon Cancer
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Author : Martin Lipkin
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Calcium Vitamin D And Prevention Of Colon Cancer written by Martin Lipkin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.


These proceedings were published as a result of a workshop sponsored by the Chemoprevention Branch of the National Cancer Institute. The workshop covered a range of topics including calcium and vitamin D in human nutrition; epidemiologic relationships betweencalcium, vitamin D, and colon cancer; the biology of calium and vitamin D at the tissue and cellular level; and enimal and human studies investigating the potential for prevention of colon cancer with calcium and vitamin D.



Mechanisms In Carcinogenesis And Cancer Prevention


Mechanisms In Carcinogenesis And Cancer Prevention
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Author : Harri U. Vainio
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Mechanisms In Carcinogenesis And Cancer Prevention written by Harri U. Vainio and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.


A large proportion of cancers is preventable. External factors, discovered by epidemiological studies during the last 50 years, account for a majority of all cancer deaths. However, still rather little is known, about how environmental and genetic factors interact, how they may regulate gene activation etc. And it is a long way from the discovery of a basic regulatory mechanism to practical patient treatment. This volume describes the present state of the art in carcinogenesis, possibilities for cancer prevention, and gives genetic background in cancer development. Attention is given to the host-environment interaction, considering how this interaction may lead to cancer formation and how it can be utilised in cancer prevention. The molecular basis for cancer development and the molecular basis for prevention are described.



Gene Mapping


Gene Mapping
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Author : Ying Gao
language : en
Publisher:
Release Date : 2007

Gene Mapping written by Ying Gao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.