Experimental Immunotoxicology
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Experimental Immunotoxicology
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Author : Ralph J. Smialowicz
language : en
Publisher: CRC Press
Release Date : 1996
Experimental Immunotoxicology written by Ralph J. Smialowicz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Business & Economics categories.
Immunotoxicology has emerged as a vital and expanding discipline over the past several years. Although the field of human immunotoxicology is arguably still in its infancy, a number of animal model systems have been well established and validated. Experimental Immunotoxicology provides an update on the recent advances in the field as it relates to animals and provokes discussion on approaches to the evaluation of human immunotoxicology. It is an important reference source for professionals in immunology and toxicology. The book begins with an overview of the mammalian immune system and covers the important role played by animal host susceptibility models. It also gives an update on immunotoxicolgy in sub-human primates. Vulnerability of bone marrow and the consequences of damage to immune function as well as chemical-induced immunosuppression as a consequence of exposure to chemicals are covered. Most of the chapters are organized to include a description of the profile of immunotoxicity, mechanisms of immunotoxicity, species comparisons and research needs.
Immunotoxicology Of Drugs And Chemicals
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Author : Jacques Descotes
language : en
Publisher:
Release Date : 2004
Immunotoxicology Of Drugs And Chemicals written by Jacques Descotes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
Investigative Immunotoxicology
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Author : Helen Tryphonas
language : en
Publisher: CRC Press
Release Date : 2005-01-27
Investigative Immunotoxicology written by Helen Tryphonas and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-27 with Medical categories.
Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discus
Principles And Methods Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Elsevier
Release Date : 2004-10-14
Principles And Methods Of Immunotoxicology written by Jacques Descotes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-14 with Science categories.
This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.
Introduction To Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Introduction To Immunotoxicology written by Jacques Descotes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Medical categories.
This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.
Immunotoxicology
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Author : The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety
language : en
Publisher: Springer Science & Business Media
Release Date : 1987-02-28
Immunotoxicology written by The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-02-28 with Medical categories.
IX The International Seminar on the Immunological System as a Target for Toxic Damage was held at The Commission of the European Communities (CEC) in Luxembourg on 6-9 November 1984. It was organized by the CEC and the International Programme on Chemical Safety of UNEP/ILO/WHO with the support of the u. S. Environmental Protection Agency and the National Institute of Environmental Health Sciences - USA and with the participation of the International Society of Immunophar macology. These bodies are actively concerned with the scientific and applied aspects of immunotoxicology. The Seminar consisted of thirty-four invited papers and three major panel discussions covering current and future test strategies for the screening of immunotoxic substances, hypersensitivity and the health implications of immunotoxico logical problems. It was attended by more than 200 scien tists from 27 countries representing all the Member states of the European Economic Community and the six Regions of the World Health Organization. These scientists represented many different disciplines and interests. The Seminar's principal objectives were: a review of recent advances in knowledge concerning the structure, function and dysfunction of the immunological system; - a review of the effects of xenobiotics on the immune system in animals and humans; an examination of the human health implications of immunotoxicity; discussion and critical analysis of the procedures for the assessment of immunological damage, a discussion of needs for the further development of laboratory and epidemiological methods and their validation, and a consideration of current test strategies.
Immunotoxicology And Risk Assessment
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Author : Dennis K. Flaherty
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08
Immunotoxicology And Risk Assessment written by Dennis K. Flaherty and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Medical categories.
This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it will incorporate new guidelines that the EPA is bringing out later this year for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both the US Food and Drug Administration, as well as data applicable to western European Nations.
Identifying And Controlling Immunotoxic Substances
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Author :
language : en
Publisher: Office of Technology Assessment
Release Date : 1991
Identifying And Controlling Immunotoxic Substances written by and has been published by Office of Technology Assessment this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Antibody-toxin conjugates categories.
Immunotoxicity Of Metals And Immunotoxicology
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Author : International Program on Chemical Safety
language : en
Publisher: Springer
Release Date : 1990-11-30
Immunotoxicity Of Metals And Immunotoxicology written by International Program on Chemical Safety and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-30 with Health & Fitness categories.
Considerable scientific and political interest has been expressed, parallelling public concern about the effects of chemicals on the immune system and the implications of those effects for health. Coupled with speculation about the magnitude and extent of the problem is discussion of needs for predictive testing and regulatory control measures. The first international seminar on the immunological system as a target for toxic damage was held in Luxembourg in 1984. It was organized by the International Programme on Chemical Safety (United Nations Environment Programme-International Labour Office World Health Organization) and the Commission of the European Communities with the support of the US Environmental Protection Agency and the National Institute of Environmental Health Sciences (USA) and the participation of the International Society of Immunopharmacology. In view of the perceived importance of imrnunotoxicity, it was considered necessary to organize a follow-up meeting. Thus, an international workshop on the immunotoxicity of metals and immuno toxicology was held in Hanover, Federal Republic of Germany, on 6-10 November 1989.
Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Elsevier Science Serials
Release Date : 2004
Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology written by Jacques Descotes and has been published by Elsevier Science Serials this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
This third thoroughly revised edition, written by a renowned expert in this rapidly expanding field, is a welcome and timely publication in the field of experimental and clinical immunotoxicology. Immunotoxicology is a young, but rapidly expanding area of toxicology. Since the second edition of this book was published in 1988, an increasing amount of data has resulted in the publication of many articles and reviews. This book covers the many general facets of current immunotoxicology - clinical, experimental, mechanistic and regulatory aspects, including a chapter on the immune system giving toxicologists unfamiliar with immunology the opportunity to acquire the minimal knowledge necessary to conduct and interpret immunotoxicity studies. A comprehensive chapter on adverse effects in relation to immunotoxicity is included in order to predict and understand the toxic effects of drugs and other chemicals in living beings. An effort is made to answer one of the perhaps most confusing issues confronting the student of immunotoxicology namely the identification of what constitutes an immunotoxic response and what does not. Researchers from different disciplines have shown interest in this new field, and presented results of their work on immunotoxicological issues from extremely varied perspectives. As a bridging discipline between immunology and toxicology, immunotoxicology is genuinely multidisciplinary, reflected in this excellent book.