Exploring Novel Roles For Cytosolic Malic Enzyme In Intestinal Tumorigenesis Using Mouse And Human Models
DOWNLOAD
Download Exploring Novel Roles For Cytosolic Malic Enzyme In Intestinal Tumorigenesis Using Mouse And Human Models PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Exploring Novel Roles For Cytosolic Malic Enzyme In Intestinal Tumorigenesis Using Mouse And Human Models book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Exploring Novel Roles For Cytosolic Malic Enzyme In Intestinal Tumorigenesis Using Mouse And Human Models
DOWNLOAD
Author : Lorenzo Mario Fernandes
language : en
Publisher:
Release Date : 2018
Exploring Novel Roles For Cytosolic Malic Enzyme In Intestinal Tumorigenesis Using Mouse And Human Models written by Lorenzo Mario Fernandes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Metabolism In Cancer
DOWNLOAD
Author : Thorsten Cramer
language : en
Publisher: Springer
Release Date : 2016-08-24
Metabolism In Cancer written by Thorsten Cramer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-24 with Medical categories.
This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
Mitochondria And Cancer
DOWNLOAD
Author : Keshav Singh
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-05
Mitochondria And Cancer written by Keshav Singh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-05 with Medical categories.
Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.
Enzyme Regulation And Metabolic Diseases
DOWNLOAD
Author : Francesco Belfiore
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1980
Enzyme Regulation And Metabolic Diseases written by Francesco Belfiore and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Clinical enzymology categories.
The Pentose Phosphate Pathway
DOWNLOAD
Author : Terry Wood
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Pentose Phosphate Pathway written by Terry Wood and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Pentose Phosphate Pathway aims to explore the pentose phosphate cycle and the practical techniques applied in its investigation. The main focus of the book is the pentose phosphate cycle in animals as well as microorganisms, and does not discuss the one related to photosynthesis. The book covers the formulation of the pathway, its types, and its alternative formulations; the preparation, processes, and analysis of the pathway; and the enzymes involved. Also covered in the book are the intermediates in intact cells and tissues; distribution of enzymes among different tissues and species; the operation, regulation, and overall control of the pathway; and the clinical, nutritional, and metabolic aspects of the pathway. The text is recommended for biologists and biochemists who would like to understand further the pentose phosphate pathway and the processes related to it.
Exploring Pancreatic Metabolism And Malignancy
DOWNLOAD
Author : Ganji Purnachandra Nagaraju
language : en
Publisher: Springer Nature
Release Date : 2019-11-23
Exploring Pancreatic Metabolism And Malignancy written by Ganji Purnachandra Nagaraju and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-23 with Medical categories.
This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an increased incidence of gastric cancers. The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy. Lastly, the book offers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy.
Plant Systems Biology
DOWNLOAD
Author : Sacha Baginsky
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-25
Plant Systems Biology written by Sacha Baginsky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-25 with Science categories.
This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
Mesenchymal Stem Cell Derived Exosomes
DOWNLOAD
Author : Yaoliang Tang
language : en
Publisher: Academic Press
Release Date : 2015-09-02
Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-02 with Medical categories.
Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
Free Fatty Acid Receptors
DOWNLOAD
Author : Graeme Milligan
language : en
Publisher: Springer
Release Date : 2018-07-13
Free Fatty Acid Receptors written by Graeme Milligan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-13 with Medical categories.
This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Advanced Research On Plant Lipids
DOWNLOAD
Author : N. Murata
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-02-28
Advanced Research On Plant Lipids written by N. Murata and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-02-28 with Science categories.
The International Symposia on Plant Lipids, the 15th of which was held in Okazaki, Japan, in May 12-17, 2002, is held every two years and is the only international meeting in this field. The almost 100 contributions from the symposium collected in this book represent the most up-to-date research results on plant lipids, including their structure, analysis, biosynthesis, regulation, physiological function, environmental aspects, and biotechnology, obtained world-wide during the last two years.