Extracellular Vesicles In Human Health And Diseases
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Extracellular Vesicles In Human Health And Diseases
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Author : Asit Ranjan Ghosh
language : en
Publisher: Springer
Release Date : 2024-07-14
Extracellular Vesicles In Human Health And Diseases written by Asit Ranjan Ghosh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-14 with Medical categories.
This book reviews the physiological and therapeutic applications of extracellular vesicles (EV) of different cell types. The initial chapter of the book focuses on their evolution, physiological functions, inter- and intra-cellular communication, and their strategic applications in defining different health disorders including aging, pathogenicity, toxicity, and drug delivery. The chapter also provides an overview of recent technologies for EV isolation, analysis, and quantification. The chapter also examines the role of EVs in viral and bacterial pathogenesis and discusses the emerging potential of EVs as diagnostic and therapeutic tools. It also discusses the emerging role of EVs including endosome-derived exosomes and fragments of the cellular plasma membrane in intercellular communication by transporting messenger RNA, microRNA (miRNA), and proteins. The book further explores the potential of membrane vesicles in the prevention, diagnosis, and treatment of inflammatory diseases,metabolic disorders, cardiovascular diseases, and neurodegenerative disorders. This book address researchers, clinicians, and doctoral and graduate students working in cellular molecular biology, cancer biology, infectious diseases, molecular medicine, biomedicine, neurobiology, microbiology, and translational medicine.
Extracellular Vesicles And Their Importance In Human Health
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Author : Ana Gil De Bona
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-04
Extracellular Vesicles And Their Importance In Human Health written by Ana Gil De Bona and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with Science categories.
Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.
Extracellular Vesicles
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Author : Juanita F. Lafon
language : en
Publisher:
Release Date : 2020-01-29
Extracellular Vesicles written by Juanita F. Lafon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-29 with Cell organelles categories.
Extracellular vesicles are small vesicles (or membrane-bound organelles) that can be found in blood and other biofluids and their internal content and surface reflect their origin and potential function. Extracellular Vesicles: Mechanisms and Role in Health and Disease begins with a summary of the most recent findings about the potential role of extracellular vesicles in human health and diseases and discusses future directions. The authors discuss how intercellular communication at the developing feto-maternal interface is of cardinal interest. The implantation itself is at least partially-dependent on extracellular vesicles' mediated processes. Furthermore, the altered local and systemic immunomodulatory state seems to be significantly influenced by proteomic and nucleic acid cargo found in extracellular vesicles. Lastly, recent studies in the development of metastatic potential are studied by focusing on the role of oxidative stress under the control of reprogrammed onco-metabolism using the LNCaP-C4-2B prostate cancer progression model system.
Extracellular Vesicles In Health And Disease
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Author : Paul Harrison
language : en
Publisher: CRC Press
Release Date : 2014-05-02
Extracellular Vesicles In Health And Disease written by Paul Harrison and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-02 with Medical categories.
Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role
Extracellular Vesicles In Health And Diseases
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Author : Paul J. Harrison
language : en
Publisher:
Release Date : 2014
Extracellular Vesicles In Health And Diseases written by Paul J. Harrison and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Extracellular Vesicles
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-07-20
Extracellular Vesicles written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-20 with Science categories.
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
Extracellular Vesicles In Cardiovascular And Metabolic Diseases
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Author : Junjie Xiao
language : en
Publisher: Springer
Release Date : 2023-08-24
Extracellular Vesicles In Cardiovascular And Metabolic Diseases written by Junjie Xiao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-24 with Medical categories.
This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
Translational Glycobiology In Human Health And Disease
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Author : Michelle Kilcoyne
language : en
Publisher: Academic Press
Release Date : 2023-11-29
Translational Glycobiology In Human Health And Disease written by Michelle Kilcoyne and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-29 with Science categories.
Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology’s growing role in human health and disease study Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciences
Mesenchymal Stem Cells In Human Health And Diseases
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Author : Ahmed El-Hashash
language : en
Publisher: Academic Press
Release Date : 2020-01-07
Mesenchymal Stem Cells In Human Health And Diseases written by Ahmed El-Hashash and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-07 with Science categories.
Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world
Exosomes
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Author : Larry Edelstein
language : en
Publisher: Academic Press
Release Date : 2019-10-16
Exosomes written by Larry Edelstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-16 with Science categories.
Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing