Fast Facts Clinical Trials In Oncology
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Fast Facts Clinical Trials In Oncology
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Author : A. Hackshaw
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2020-12-18
Fast Facts Clinical Trials In Oncology written by A. Hackshaw and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-18 with Medical categories.
Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are described, as are trials of surgical procedures, radiation therapy and advanced therapies. The processes and documentation required to set up and conduct a trial are outlined, and the authors describe how trial data and real-world evidence are used to improve care. Although this concise colorful book focuses on oncology, the principles apply equally to interventions in other areas of practice. It will prove invaluable to medical, pharmaceutical and allied health professionals who want, or need, an overview of how contemporary clinical trials are designed and conducted.
Fast Facts Clinical Trials In Oncology
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Author : Allan Hackshaw
language : en
Publisher:
Release Date : 2021
Fast Facts Clinical Trials In Oncology written by Allan Hackshaw and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Fast Facts Medical Statistics
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Author : R. Kay
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2020-07-17
Fast Facts Medical Statistics written by R. Kay and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-17 with Medical categories.
Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods
Fast Facts Immuno Oncology
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Author : Stephen Clarke
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2021-07-07
Fast Facts Immuno Oncology written by Stephen Clarke and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-07 with Medical categories.
The treatment of cancer has been revolutionized by therapies that modulate the immune system, with benefits for quality of life and survival. Standards of care have changed to reflect developments, but the area is moving fast. Keeping abreast of new therapies and trial data can be challenging. This second edition of 'Fast Facts: Immuno-Oncology' takes you from the fundamentals of immunology through to the new concepts of immunoediting and immunotherapy and likely future directions. Whether you have worked in oncology for decades and need a refresher or you are just starting out and need a crash course, this book provides all you need to know about immuno-oncology, concisely summarized. Table of Contents: • Components of the immune system • How cancers evade the immune system • How cancer immunotherapy works • Clinical use of immune checkpoint inhibitors • The future of immuno-oncology
Fast Facts Breast Cancer
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Author : Jayant Sharad Vaidya
language : en
Publisher:
Release Date : 2014-06-02
Fast Facts Breast Cancer written by Jayant Sharad Vaidya and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-02 with Medical categories.
Wherever you are in your career, and whatever involvement you have with caring for women with breast cancer, the fifth edition of 'Fast Facts: Breast Cancer' has something for you. The world-class authors of this popular fact-packed handbook provide practical advice on all the key areas of breast cancer management, from risk factors and diagnosis to treatment of all cancer stages. But what really makes it stand out from the crowd is the authors' awareness of the information you need when you talk to a woman concerned about breast cancer. The chapter dedicated to perception of risk will refresh your knowledge and help you talk to your patients about their individual prospects, while the short chapter on clinical trials will help you discuss potential participation in trials and answer common questions. Improvements in the management of breast cancer have followed three major themes in recent years: greater optimization of individualized local treatment, longer duration of therapies, and the use of biological therapies targeted at specific receptors. This colorful up-to-date handbook addresses all these trends, alongside the disturbing issues of overdiagnosis as a result of screening and overtreatment. Given the explosion in information technology, patients and their families have access to much more information on their condition and as a result assume a more active role in their medical management. Health professionals have an important role in helping patients sort the facts from the fallacies, put the risks and benefits into perspective and balance their treatment choices. For this reason alone, 'Fast Facts: Breast Cancer' is an invaluable evidence-based resource for everyone working in breast cancer care in primary and secondary settings, from medical and nursing students, to GPs, specialist nurses and residents. And one for your patients too ... The authors encourage you to make your patients well-informed active partners in their breast cancer care by sharing this highly readable book with them. Contents: * Risk factors * Perception of risk * Pathophysiology * Diagnosis * Local control of primary tumor * Adjuvant therapy * Follow-up and rehabilitation * Management of advanced cancer * Clinical trials * Future trends * Useful resources
Fast Facts Non Small Cell Lung Cancer
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Author : Mary O'Brien
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2016-08-22
Fast Facts Non Small Cell Lung Cancer written by Mary O'Brien and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-22 with Medical categories.
Rapid developments in the classification, screening and treatment of non-small-cell lung cancer (NSCLC) are improving outcomes for patients with the disease. This insightful guide is designed to bring you up to speed with recent advances, including: • the latest CT-based screening and interval growth imaging techniques • proposed changes to the TNM classification system • the increasing trend for minimally invasive and lung-sparing surgery • stereotactic radiation for early-stage tumors • new targeted therapies • breakthroughs in personalized medicine. Today's developments will change tomorrow's standards of care. 'Fast Facts: Non-Small-Cell Lung Cancer' is important reading for all health professionals and medical trainees working in this fast-moving area.
Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias
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Author : Karthik Ramasamy
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-01-09
Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias written by Karthik Ramasamy and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-09 with Medical categories.
Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care
Fast Facts Ovarian Cancer
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Author : Christina Fotopoulou
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-05-09
Fast Facts Ovarian Cancer written by Christina Fotopoulou and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-09 with Medical categories.
When it comes to detecting, diagnosing and treating women who have, or are suspected of having, ovarian cancer, there are significant opportunities for well-informed healthcare professionals to intervene in a meaningful way. 'Fast Facts: Ovarian Cancer' examines the areas that will have the biggest effect in clinical practice, including: • the evidence for and against screening • the valuable role of genetic testing in identifying at-risk women • if and when to operate • strategies to overcome platinum resistance • the impact of targeted therapies. From the tools that will help establish a swift diagnosis to the risks and benefits of palliative salvage surgery, this refreshingly readable resource captures the key knowledge that every busy healthcare professional needs in order to make better health decisions for patients with ovarian cancer. Contents: • Epidemiology and prevention • Pathophysiology and classification • Genetic testing • Diagnosis, staging and grading • Surgery • Chemotherapy • Recurrent ovarian cancer • Targeted therapies • Non-epithelial ovarian cancers • Follow-up and palliative surgery • Useful resources
Fast Facts Molecular Profiling In Solid Tumors
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Author : P. Cheema
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2022-12-06
Fast Facts Molecular Profiling In Solid Tumors written by P. Cheema and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Medical categories.
Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results. Table of Contents: • Molecular profiling: the basics • Rationale for testing • Sample collection • Test selection and process • Interpreting the report • Talking to patients • Challenges and opportunities
Fast Facts Biosimilars In Hematology And Oncology
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Author : P. Cornes
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2020-01-24
Fast Facts Biosimilars In Hematology And Oncology written by P. Cornes and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-24 with Medical categories.
Biologics have revolutionized – and are revolutionizing – the treatment of many serious disorders. The evidence acquired from more than 10 years of clinical experience, with more than 50 biosimilar drugs and more than 700 million patient-days' exposure in Europe, shows that approved biosimilars can be used as safely and effectively as originator biologics. Yet concerns persist about biosimilars – particularly in curative cancer treatment, where they are relatively recent therapeutic options. 'Fast Facts: Biosimilars in Hematology and Oncology' provides a concise overview of emerging global practice in this fast-moving area together with practical information on adding biosimilars to a formulary and switching patients. Contents: • Biologics and the need for biosimilars • Why do we need biosimilars? • How is the quality of biosimilar medicines assured? • Legal issues • Switching, interchangeability and extrapolation • Safety and pharmacovigilant • Global issues • Formulary considerations: pharmacy issues • Formulary considerations: supportive care biosimilars • Formulary considerations: therapeutic anti-cancer biosimilars • Communication and awareness