Fatty Acids And Inflammatory Skin Diseases
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Fatty Acids And Inflammatory Skin Diseases
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Author : Schröder
language : en
Publisher: Springer
Release Date : 2013-03-12
Fatty Acids And Inflammatory Skin Diseases written by Schröder and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Medical categories.
Fatty acids play an important role in the barrier function of skin and represent a major source of proinflammatory mediators such as prostaglandins, leukotrienes and other lipids in inflammatory skin disorders. This book combines the two major functions of fatty acids in skin biology. In the first part the biosynthesis of fatty acids in skin with its role in barrier function as well as the role of dietary fatty acids on skin cell function and in the treatment of inflammatory skin diseases is presented. The second part deals with skin as a source of proinflammatory eicosanoids, especially with the keratinocyte as a major cellular source. Metabolism of eicosanoids in skin, its role in psoriasis and atopic dermatitis as well as pharmacological inhibition of eicosanoid biosynthesis is reviewed. The book finishes with a chapter describing the methods used for quantification of fatty acids and derivatives in skin inflammation. Anyone interested in skin physiology would benefit from the overviews about the two sites of fatty acids' function in skin integrity and in skin inflammation.
Fatty Acids And Inflammatory Skin Diseases
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Author : Jens-Michael Schröder
language : en
Publisher: Birkhauser
Release Date : 1999
Fatty Acids And Inflammatory Skin Diseases written by Jens-Michael Schröder and has been published by Birkhauser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Targeting Human Inflammatory Skin Diseases With Natural Products Exploring Potential Mechanisms And Regulatory Pathways
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Author : Bey Hing Goh
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-07
Targeting Human Inflammatory Skin Diseases With Natural Products Exploring Potential Mechanisms And Regulatory Pathways written by Bey Hing Goh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-07 with Science categories.
Medicinal Fatty Acids In Inflammation
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Author : J. Kremer
language : en
Publisher: Springer
Release Date : 2013-03-11
Medicinal Fatty Acids In Inflammation written by J. Kremer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-11 with Medical categories.
This volume of Progress in Inflammation Research is a unique compilation of work performed by a wide spectrum of investigators from different medical disciplines. It is fascinating that dietary alterations of fatty acid intake can result in a range of salutory changes in a great variety of medical conditions. Most of the good scien tific work which has led to these observations has been performed over just the last two decades. This is of course not a very long time in the context of the history of the human species. Recently performed analysis of fat intake from paleolithic times has indicated that our hunter-gatherer ancestors consumed as much cholesterol as modern Western man, but strikingly less saturated fatty acid and more polyunsatu rates, including n-3 fatty acids. Wild game has the terrestrial source of n-3 incorpo rated in its fat since browsing animals derive 18:3n-3 (alpha-linolenic acid) natural ly from leafy plants. There is, however, little opportunity for modern Western man to get n-3 fatty acids from the diet if one does not consume fish. Modern agribusiness provides ani mal feeds high in n-6 fatty acids, mostly derived from linoleic acid (18:2n-6) in corn feed. Therefore, grazing animals have no access to alternative fatty acids in either feed or grasses, the latter containing little or none of these potentially beneficial highly polyunsaturated fatty acids.
Methodologies Tools And Techniques To Study Fatty Acids Mechanisms Of Action In Atopic Dermatitis
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Author : Keerthi Anantha
language : en
Publisher:
Release Date : 2014
Methodologies Tools And Techniques To Study Fatty Acids Mechanisms Of Action In Atopic Dermatitis written by Keerthi Anantha and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Atopic dermatitis categories.
Bioactive Dietary Factors And Plant Extracts In Dermatology
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Author : Ronald Ross Watson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-28
Bioactive Dietary Factors And Plant Extracts In Dermatology written by Ronald Ross Watson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Medical categories.
The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research.
Eicosanoids And The Skin
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Author : Thomas Ruzicka
language : en
Publisher: CRC Press
Release Date : 1990-03-30
Eicosanoids And The Skin written by Thomas Ruzicka and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-03-30 with Medical categories.
This publication summarizes the increasing knowledge in eicosanoid research. It provides a detailed overview of this rapidly expanding field. The text contains sections on general aspects of arachidonic acid metabolism, the role of eicosanoids in skin diseases, and their biological and biochemical effects in skin. Also included is a section on inhibitors of arachidonic acid metabolism with particular reference to use in dermatology. New concepts covered are: possible physiological role of lipoxygenase products in cutaneous wound healing, restoration and maintenance of cutaneous integrity, and the recently recognized protective function of prostaglandins in skin. It is an invaluable resource for individuals involved with dermatology, pharmacology, inflammation, immunology, biochemistry, physiology, internal medicine and therapeutics.
Nutraceuticals And The Skin Roles In Health And Disease
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Author : Jean Christopher Chamcheu
language : en
Publisher: MDPI
Release Date : 2018-10-08
Nutraceuticals And The Skin Roles In Health And Disease written by Jean Christopher Chamcheu and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-08 with categories.
This book is a printed edition of the Special Issue "Nutraceuticals and the Skin: Roles in Health and Disease" that was published in Nutrients
The Short Chain Fatty Acid Sodium Butyrate Attenuates Imiquimod Induced Psoriasis Like Skin Inflammation
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Author : Anika Bruhs
language : en
Publisher:
Release Date : 2017
The Short Chain Fatty Acid Sodium Butyrate Attenuates Imiquimod Induced Psoriasis Like Skin Inflammation written by Anika Bruhs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
We have recently shown that topical application of sodium butyrate (SB) suppresses allergic contact dermatitis in mice. This effect was associated with the induction/activation of Treg, the activity of which is diminished in certain inflammatory dermatoses. To further study the effects of SB in chronic inflammatory skin disorders, we utilized the imiquimod (IMQ)-induced psoriasis-like skin inflammation model. Mice were treated with 5% IMQ cream (Aldarau00ae) on the shaved backs and ears for 10 days. One group of IMQ-treated mice received topically on the back skin 100 u00b5l of a 1 mM solution SB for 3 days. IMQ-treated mice developed thickening of the skin, erythema, scales as well as acanthosis, hyperkeratosis and inflammatory infiltrates. These inflammatory responses were significantly reduced upon administration of SB. On the RNA level, SB treatment leads to significant downregulation of Il17 transcription. In turn, transcription of Il10 was remarkably induced by SB. We surmise Treg to be the primary source of IL-10 which was supported by the upregulation of the mRNA of the Treg-specific transcription factor FOXP3. Together, these data support our assumption that SB might activate cutaneous Treg and thereby contribute to the downregulation of the inflammatory response. Though only topically applied, IMQ induces also systemic immunologic alterations. The number of IL-17-expressing CD45+ cells obtained from lymph nodes and spleens was remarkably enhanced in IMQ-treated mice, implying that the splenomegaly observed in IMQ treated mice may be in part due to the infiltration/expansion of IL-17+ lymphocytes. This effect was almost completely prevented by SB. In addition, significantly fewer CD45+ cells expressing FOXP3 and IL-10 were detected after IMQ administration, suggesting downregulation of Treg. Together, this implies that IMQ suppresses Treg and activates IL-17-expressing lymphocytes an effect which can be dramatically reversed by SB, explaining the beneficial effect of SB on the resolution of the IMQ-induced psoriasis-like lesions.
Handbook Of Diet Nutrition And The Skin
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Author : Victor R. Preedy
language : en
Publisher: Springer
Release Date : 2012-05-23
Handbook Of Diet Nutrition And The Skin written by Victor R. Preedy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-23 with Science categories.
Studies have clearly shown that optimal diet and nutrition can prevent skin disease. Moreover, novel nutritional components have been used experimentally to treat skin conditions. However, the clinical application of these nutrients awaits confirmation. It is thus up to health care professionals to present new knowledge in order to provide advice or treatments for skin problems. This handbook provides, in a single volume, comprehensive coverage of the relation between skin and diet and nutrition in its broadest sense. The Handbook of diet, nutrition and the skin consists of sections on general aspects of skin, nutrition and diet, micronutrients, nutraceuticals, cancer and specific skin conditions. Unique features of each chapter in this volume include relevant and useful 'key facts' which highlight interesting or important findings of the specific subjects and 'summary points' that are designed to abstract each chapter in take home messages. This handbook will be of interest to a wide range of readers, such as dermatologists, doctors, nurses and those interested in, or working within the area of skin health. This will of course also include nutritionists and dieticians, dermatologists, cosmetic scientists, health workers and practitioners, college and university lecturers and undergraduate and graduate students.