Fetal Islet Transplantation
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Fetal Islet Transplantation
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Author : B. Formby
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Fetal Islet Transplantation written by B. Formby and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Despite the advent of insulin for clinical use in 1922, our ability to control hypergly cemia and prevent the long term sequelae ofthe disease remains limited. Thus normalization of the milieu interieur with physiologic responses of insulin and metabolites remains an elusive but critically important goal. The developing endocrine pancreas provides a model system that speaks to many challenges of the transplantation biologist. Thus the attempt to of vascularization, growth and development, immunologic toler recapitulate the ontogeny ance, and glucose responsive insulin secretory capacity of fetal islet tissue provides a tantalizing possibility to replace insulin secreting tissue in persons with diabetes. Studies of this tissue are also important because of the implications such investigations have for genetic and molecular biological approaches to restoring insulin secretion as well as for providing clues to enhancing the growth and repair of islets that have been the target of autoimmune disease. Investigators in the area offetal islet transplantation comprise a small group scattered throughout the world scientific community. Therefore it seemed important to provide a forum where these scientists could gather, share ideas, and achieve consensus such that progress in this rapidly evolving area could be facilitated. The conference would have remained a dream if the support of the Okla Basil Meade, Jr. family had not made it manifest.
Fetal Islet Transplantation
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Author : Lois Jovanovic
language : en
Publisher: Springer Science & Business Media
Release Date : 1995
Fetal Islet Transplantation written by Lois Jovanovic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
Proceedings of the October 1994 symposium at Sansum Medical Research Foundation in Santa Barbara, CA, focus on the use of fetal islet tissue in controlling diabetes and repairing islets that have been damaged by autoimmune disease. Papers detail research on fetal islet growth, differentiation, immunology, and transplantation. Other topics include fetal islet transplantation and pregnancy, and networking for the collection of fetal islet tissues. Annotation copyright by Book News, Inc., Portland, OR
Human Fetal Tissue Transplantation
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Author : Niranjan Bhattacharya
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-26
Human Fetal Tissue Transplantation written by Niranjan Bhattacharya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Medical categories.
Many diseases earlier considered to be incurable are now being treated with modern innovations involving fetal tissue transplants and stem cells derived from fetal tissues. Fetal tissues are the richest source of fetal stem cells as well as other varying states of differentiated cells and support or stromal cells. The activity of such stem cells is at their peak provided they are given the correct niche. Stem cells, as we know, are immortal cells with the capacity to regenerate into any kind of differentiated cell as per niche-guidance. As such, fetal tissues have the potential capacity to mend, regenerate and repair damaged cells or tissues in adults, when directly transplanted to the site of injury, or even when transplanted in some other site, because it may have a homing capacity to migrate to the site of the specific injured organ. This is a new area of translational research and needs to be highlighted because of its immense potential. This book will bring together the new work of prominent medical scientists and clinicians who are conducting pioneering research in human fetal tissue transplantation. This will include direct transplant of healthy fetal tissue into mature patients as well as in hosts with genetic diseases. Transplant techniques, donor-host interaction, cell and tissue storage, ethical and legal issues, are some of the many matters which the book will deal with.
Fetal Tissue Transplants In Medicine
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Author : Robert G. Edwards
language : en
Publisher: Cambridge University Press
Release Date : 1992-11-05
Fetal Tissue Transplants In Medicine written by Robert G. Edwards and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-11-05 with Medical categories.
The most recent scientific and clinical developments and techniques in fetal tissue transplants are presented, including both the transplantation of fetal tissue into mature recipients, and the grafting of donor cells into fetuses that are known to be carrying genetic disease.
Methods In Islet Transplantation Research
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Author :
language : en
Publisher:
Release Date : 1990
Methods In Islet Transplantation Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Islands of Langerhans categories.
Procurement Of Pancreatic Islets
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Author : Robert Paul Lanza
language : en
Publisher: CRC-Press
Release Date : 1997-09-01
Procurement Of Pancreatic Islets written by Robert Paul Lanza and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-09-01 with Medical categories.
Examines current methods of procuring and preserving the pancreas. Approaches to pancreatic tissue digestion and islet purification, collagenese selection and islet isolation from rodents are discussed.
Transplantation Of Fetal Pig Islet Like Cell Clusters As Therapy For Diabetes
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Author : Sophia Dean
language : de
Publisher:
Release Date : 2008-04-01
Transplantation Of Fetal Pig Islet Like Cell Clusters As Therapy For Diabetes written by Sophia Dean and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-01 with Medical categories.
Type 1 diabetes is an autoimmune disease in which the insulin-producing cells of the pancreas are destroyed. Complications that arise from type 1 diabetes include blindness, kidney failure and nerve damage. Current treatment is with daily insulin injections, although some may be eligible for a pancreas or islet transplant. However, this is usually reserve for those with end-stage kidney failure. Furthermore, there are not enough donors to meet this demand should every diabetic receive a pancreas or islet transplant. It is for this reason that alternative sources of insulin-producing cells must be considered as another form of treatment. In this book, the transplantation of insulin cells from the fetal pig pancreas is examined as an alternative therapy, with the use of the outbred pig as an animal model for type 1 diabetes. A historical perspective of diabetes is also discussed as well as the different types of anti-rejection drugs used and the mechanisms of graft rejection. Finally, the possibility of eliminating the need for anti-rejection drugs through the means of encapsulation, is explored.
Immunomodulation Of Pancreatic Islets
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Author : Lanza
language : en
Publisher: CRC-Press
Release Date : 1994
Immunomodulation Of Pancreatic Islets written by Lanza and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
The Foetus As Transplant Donor
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Author : Peter McCullagh
language : en
Publisher:
Release Date : 1987-05
The Foetus As Transplant Donor written by Peter McCullagh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-05 with Medical categories.
The ethical issues sourrounding foetal experimentation have been under constant debate since the early 1970s. This book analyzes all aspects of foetal experimentation and suggests answers to the difficult questions concerning its morality and uses, as well as the difficulties associated with diagnosing foetal brain death. Explores the moral implications of experimental, as opposed to therapeutic, rationales for experimentation on foetal subjects. Also offers historical background on current perceptions of the suitability of foetal tissue for transplantation, how current claims have been derived from earlier practice, and the manner in which proposals for transplantation of one specific type of foetal tissue, the pancreas, have been presented to the community.
Pancreas Islet And Stem Cell Transplantation For Diabetes
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Author : Nadey S. Hakim
language : en
Publisher: Oxford University Press, USA
Release Date : 2010-08-26
Pancreas Islet And Stem Cell Transplantation For Diabetes written by Nadey S. Hakim and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-26 with Health & Fitness categories.
This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and pancreatic stem cell transplantation, reflecting recent advances in the field, including the growing interest in stem cell research applicable to this condition.