Pancreas Islet And Stem Cell Transplantation For Diabetes

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Pancreas Islet And Stem Cell Transplantation For Diabetes

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Author : Nadey S. Hakim
language : en
Publisher: Oxford University Press, USA
Release Date : 2010-08-26

Pancreas Islet And Stem Cell Transplantation For Diabetes written by Nadey S. Hakim and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-26 with Health & Fitness categories.

This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and pancreatic stem cell transplantation, reflecting recent advances in the field, including the growing interest in stem cell research applicable to this condition.

Stem Cell Therapy For Diabetes

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Author : Shimon Efrat
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-01

Stem Cell Therapy For Diabetes written by Shimon Efrat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-01 with Medical categories.

Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

Pancreatic Stem Cells

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Author : Juan Domínguez-Bendala
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-18

Pancreatic Stem Cells written by Juan Domínguez-Bendala and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-18 with Science categories.

From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.

Pancreas And Islet Transplantation

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Author : Nadey S. Hakim
language : en
Publisher:
Release Date : 2002

Pancreas And Islet Transplantation written by Nadey S. Hakim and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.

Diabetes Mellitus is the principle cause of kidney failure and blindness in adults and leads to more cases of amputation and impotence than any other disease. It is one of the most common chronic diseases in childhood. The aims of pancreas or islet transplantation are to improve the quality of life of patients with insulin dependent diabetes mellitus and to ameliorate secondary complications. This book provides a comprehensive and international review of the recent advances in pancreas and islet transplantation. It covers surgical techniques, issues surrounding organ preservation, immunosuppression and the control of other complications, all of which contribute to the potential for such transplantations to evolve as the treatment of choice for insulin dependent diabetes. The editors have compiled a strong and international team of contribution authors. This book is essential reading for transplant surgeons and all those involved in researching or treating diabetes mellitus.

Islet Transplantation And Beta Cell Replacement Therapy

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Author : A. M. James Shapiro
language : en
Publisher: CRC Press
Release Date : 2007-07-25

Islet Transplantation And Beta Cell Replacement Therapy written by A. M. James Shapiro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-25 with Medical categories.

Beta cell replacement through transplantation remains the only treatment option for Type 1 diabetes enabling restoration of near-physiological glucose levels without significant hypoglycemia. Outlining the most recent advances and research breakthroughs, this practical guide and reference work explores the impact of islet cell transplantation and b

Transplantation Bioengineering And Regeneration Of The Endocrine Pancreas

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Author : Giuseppe Orlando
language : en
Publisher: Academic Press
Release Date : 2019-11-10

Transplantation Bioengineering And Regeneration Of The Endocrine Pancreas written by Giuseppe Orlando and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-10 with Science categories.

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation, also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Addresses imaging, treatment, scaffold technology, the use of stem cells to generate insulin, 3D printing, and more Offers an update on the progress of regenerative medicine research aimed at beta cell replacement for the treatment of diabetes

Pancreatic Islet Biology

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Author : Anandwardhan A. Hardikar
language : en
Publisher: Springer
Release Date : 2016-10-25

Pancreatic Islet Biology written by Anandwardhan A. Hardikar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.

This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.

Pluripotent Stem Cell Therapy For Diabetes

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Author : Lorenzo Piemonti
language : en
Publisher: Springer Nature
Release Date :

Pluripotent Stem Cell Therapy For Diabetes written by Lorenzo Piemonti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.

Pancreas And Beta Cell Replacement

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Author : Wayne Hawthorne
language : en
Publisher: Academic Press
Release Date : 2022-04-21

Pancreas And Beta Cell Replacement written by Wayne Hawthorne and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-21 with Science categories.

Pancreas and Beta Cell Replacement is the inaugural volume of the Regenerative and Transplant Medicine series. The idea for this new book series spawned from the observation that the regenerative medicine field is progressing at such a fast pace that the way we currently think and practice transplant medicine is rapidly changing, faster than we could ever imagine. This series was therefore conceived to bring together experts from both the transplant and regenerative medicine fields, to share knowledge first, but also to introduce the transplant audience to the remarkable progress that has occurred in regenerative medicine over the past few decades. At the same time, we intend to illustrate to researchers and operators in the regenerative medicine field the numerous platforms that transplant medicine offers for the application of their technologies. To the publisher and the editors of this series and volumes there is no doubt that regenerative medicine will shape and define the future of transplant medicine. This volume focuses on pancreas and beta cell replacement and illustrates how progress in biomaterial sciences, stem cell biology, gene editing, cell, tissue and organ bioengineering and regeneration, along with advances in xenotransplantation are revolutionizing the field. Written by the world’s experts in the fields of pancreas, islet and xenotransplantation, as well as regenerative medicine, it represents a valuable educational tool for those in the fields of clinical transplantation, researchers in the field of regenerative medicine, transplant medicine, diabetes and immunology, as well as for medical and health science students, those in academia, the biotech industry and regulatory agencies working to advance the field. At the end of the book, it will become clear to the reader that beta cell replacement offers a vast array of platforms for the application of regenerative medicine technologies to transplant medicine. First volume in the Regenerative and Transplant Medicine series, focusing on the pancreas Includes an overview of the field, including developments of transplantation methods and techniques Builds on previous works and demonstrates how regenerative and transplant medicine work together to provide an increased ability to improve health care outcomes for individuals

Pancreatic Islet Isolation

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Author : Miriam Ramírez-Domínguez
language : en
Publisher: Springer
Release Date : 2016-09-01

Pancreatic Islet Isolation written by Miriam Ramírez-Domínguez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-01 with Science categories.

Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.