Pancreatic Islet Biology
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Pancreatic Islet Biology
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Author : Anandwardhan A. Hardikar
language : en
Publisher: Springer
Release Date : 2016-10-25
Pancreatic Islet Biology written by Anandwardhan A. Hardikar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.
This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.
Pancreatic Islet Isolation
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Author : Miriam Ramírez-Domínguez
language : en
Publisher: Springer
Release Date : 2016-09-01
Pancreatic Islet Isolation written by Miriam Ramírez-Domínguez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-01 with Science categories.
Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
The Islets Of Langerhans
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Author : Md. Shahidul Islam
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
The Islets Of Langerhans written by Md. Shahidul Islam and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.
When new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained something on more or less eve- thing about the islets. At the same time, I wished it contained information as recent as possible. There are a few such books in the market but they are pretty outdated. I started picking islets myself from October 1990, when I joined the Rolf Luft Center, Karolinska Institutet. Over the years my fascination for islet research remained high. Since last year, I felt a stronger urge to do more for these mysterious and hidden mini-organs that are directly or indirectly involved in the pathogenesis of all forms of diabetes that affects ?250 million people in the world. After I launched the Islet (landesbioscience. com/journals/islets) and founded the Islet Society (isletso- ety. org), there was a momentum that could be utilized to create something equally meaningful i. e. this book. The idea cracked in September 2008. Starting September 19, 2008, I contacted an estimated 90% of the authors who published anything on the islets during 2007–2008 and who could be traced from the internet.
The Biology Of The Pancreatic Cell
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Author : S.L. Howell
language : en
Publisher: Elsevier
Release Date : 1999-04-15
The Biology Of The Pancreatic Cell written by S.L. Howell and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-04-15 with Science categories.
As a result of the key advances made more than 30 years ago, specifically the ability to isolate islets of Langerhans from the pancreas, the ability to measure insulin accurately by immunoasay, and the development of microchemical techniques for studying cells and their components, many research volumes, symposium reports, and original papers have been produced. This explosion of interest has probably had at least three stimuli: 1. the inherent scientific interest in understanding secretion of the pancreatic ß-cell2. the ß-cells relevance to a very common disease3. the availability of funding from specific sources related to diabetes research, for instance, Juvenile Diabetes Foundation International and the British Diabetic Association. As a result of all this activity, detailed scientific literature including research reviews are readily available. Surprisingly enough, there are relatively few attempts to summarize this great bulk of knowledge in a way that is accessible to the newcomer to this field and this book is intended to bridge this gap.
Molecular Biology Of The Islets Of Langerhans
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Author : Hiroshi Okamoto
language : en
Publisher: Cambridge University Press
Release Date : 1990-02-22
Molecular Biology Of The Islets Of Langerhans written by Hiroshi Okamoto and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-02-22 with Health & Fitness categories.
The islets of Langerhans, the primary source of hormone production in the pancreas, have been the focus of research into the nature of diabetes for decades. In recent years, the molecular biology of this multiendocrine organ has been intensively investigated, with a corresponding increase in our understanding of the normal and pathological functioning of islet cells.
Betasys
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Author : Bernhelm Booß-Bavnbek
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-02
Betasys written by Bernhelm Booß-Bavnbek and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-02 with Science categories.
BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.
Pancreatic Islet Cell Regeneration And Growth
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Author : Aaron I. Vinik
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pancreatic Islet Cell Regeneration And Growth written by Aaron I. Vinik and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Aaron I. Vinik, M.D., Ph.D. I IEastem Virginia Medical School The Diabetes Institutes Norfolk, Virginia 23510 This symposium, held in June 1991, was a gathering of international scientists to exchange their views on current concepts of cell growth and differentiation. Each scientist was asked to present a topic of their research related to cell growth and regeneration and to participate in a round table conference elaborating on current knowledge and sharing their experiences. By furthering this promising area of endeavor, a means of understanding ontogeny of cell development and of providing insights into tumor biology would prevail. Of prime importance was the anticipation that new information from a better understanding of the normal evolution of the pancreatic islet would generate alternative approaches to curing diabetes. This forward serves as a short introduction to the concept of pancreatic islet regeneration and the models currently in use to study the process. DEVELOPMENTAL ORIGIN OF ISLETS DURING EMRYOGENESIS The developing pancreas appears as a protrusion from the dorsal surface of the l embryonic gut. The different islet cell types appear sequentially during development in vivo. It therefore seems reasonable to propose that coordinated growth is dependent upon specificity of growth factors.
Pancreatic Stem Cells
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Author : Juan Domínguez-Bendala
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-10
Pancreatic Stem Cells written by Juan Domínguez-Bendala and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-10 with Science categories.
From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.
Islet Inflammation And Metabolic Homeostasis
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Author : Jason Collier
language : en
Publisher: MDPI
Release Date : 2021-06-08
Islet Inflammation And Metabolic Homeostasis written by Jason Collier and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-08 with Science categories.
This book provides a resource for the science or medical professional interested in islet biology. With a mix of review articles and studies showing primary data, new advances in islet inflammation and metabolic homeostasis are highlighted. The topics are succinctly presented by distinct viewpoints. An introduction to the Special Issue, with summaries of the studies included, is provided by the Guest Editors.
The Pancreatic Beta Cell
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Author :
language : en
Publisher: Academic Press
Release Date : 2014-02-20
The Pancreatic Beta Cell written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-20 with Medical categories.
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways