The Biology Of The Pancreatic Cell
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The Biology Of The Pancreatic Cell
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Author : S.L. Howell
language : en
Publisher: Elsevier
Release Date : 1999-04-15
The Biology Of The Pancreatic Cell written by S.L. Howell and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-04-15 with Science categories.
As a result of the key advances made more than 30 years ago, specifically the ability to isolate islets of Langerhans from the pancreas, the ability to measure insulin accurately by immunoasay, and the development of microchemical techniques for studying cells and their components, many research volumes, symposium reports, and original papers have been produced. This explosion of interest has probably had at least three stimuli: 1. the inherent scientific interest in understanding secretion of the pancreatic ß-cell2. the ß-cells relevance to a very common disease3. the availability of funding from specific sources related to diabetes research, for instance, Juvenile Diabetes Foundation International and the British Diabetic Association. As a result of all this activity, detailed scientific literature including research reviews are readily available. Surprisingly enough, there are relatively few attempts to summarize this great bulk of knowledge in a way that is accessible to the newcomer to this field and this book is intended to bridge this gap.
The Pancreatic Beta Cell
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Author :
language : en
Publisher: Academic Press
Release Date : 2014-02-20
The Pancreatic Beta Cell written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-20 with Medical categories.
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways
Pancreatic B Cell Biology In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-04-06
Pancreatic B Cell Biology In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-06 with Science categories.
Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more. Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease. Provides updated and extensive review articles that focus on different aspects of pancreatic cell biology Offers a wide range of perspectives for basic and translational research Includes original figures that help readers understand the complex pathways involved in cell function in homeostasis and under pathogenic conditions
The Pancreas
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Author : Vay Liang W. Go
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1993
The Pancreas written by Vay Liang W. Go and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
This second, revised edition aims to incorporate the latest advances in research and clinical practice, and has been refocused to provide complete coverage of the endocrine, as well as the exocrine, functions of the pancreas. Over 80 experts provide a definitive account of the biology of the pancreas and the pathobiology, diagnosis, and medical and surgical treatment of all pancreatic diseases.
Betasys
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Author : Bernhelm Booß-Bavnbek
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-02
Betasys written by Bernhelm Booß-Bavnbek and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-02 with Science categories.
BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.
Pancreatic Stem Cells
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Author : Juan Domínguez-Bendala
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-10
Pancreatic Stem Cells written by Juan Domínguez-Bendala and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-10 with Science categories.
From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.
Pancreatic Beta Cell In Health And Disease
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Author : Susumu Seino
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-08
Pancreatic Beta Cell In Health And Disease written by Susumu Seino and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-08 with Science categories.
The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.
Pancreatic Islet Biology
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Author : Anandwardhan A. Hardikar
language : en
Publisher: Springer
Release Date : 2016-10-25
Pancreatic Islet Biology written by Anandwardhan A. Hardikar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.
This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.
Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes
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Author : David J. Hill
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-12-02
Control Of Pancreatic Beta Cell Function And Plasticity In Health And Diabetes written by David J. Hill and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-02 with Science categories.
Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.
Pancreatic Stem Cells
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Author : Juan Domínguez-Bendala
language : en
Publisher: Humana Press
Release Date : 2010-11-16
Pancreatic Stem Cells written by Juan Domínguez-Bendala and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-16 with Science categories.
From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.