Fibrosis Inflammation And Cancers Dangerous Liaisons To Be Depicted And Targeted
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Fibrosis Inflammation And Cancers Dangerous Liaisons To Be Depicted And Targeted
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Author : Denisa Baci
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-22
Fibrosis Inflammation And Cancers Dangerous Liaisons To Be Depicted And Targeted written by Denisa Baci and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-22 with Medical categories.
Cancer Rnome Nature Evolution
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Author : Mansi Arora
language : en
Publisher: Springer
Release Date : 2018-11-15
Cancer Rnome Nature Evolution written by Mansi Arora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-15 with Medical categories.
In the last decade, researchers working in the field of cancer biology have shifted their focus from genetic defects to epigenetic dysregulation, especially that of non-coding RNAs (ncRNAs). This book encompasses a comprehensive review of the transcriptional landscape of the cell and its involvement in the cancer pathophysiology. The first two chapters elucidate the basics of biosynthesis, mechanism of action and modulation of the epigenetic regulation of gene expression by coding as well as non-coding RNAs. The third chapter discusses the aberrant expression of the cellular RNome in the cancer cells and highlights its role in the orchestration of processes involved in evolution as well as the sustenance of cancer cells. The fourth chapter describes the recent advances in the field of translating the transcriptome into diagnostic/prognostic biomarkers and as targets for novel anti-cancer therapies. The final chapter then reviews the emerging experimental approaches to screen, identify and explore the functions of ncRNAs. Providing valuable insights into the field of RNome in the context of cancer, this book is helpful to students, researchers and clinicians..
Fundamentals Of Medical Surgical Nursing
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Author : Anne-Marie Brady
language : en
Publisher: John Wiley & Sons
Release Date : 2014-01-28
Fundamentals Of Medical Surgical Nursing written by Anne-Marie Brady and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-28 with Medical categories.
Fundamentals of Medical-Surgical Nursing Fundamentals of Medical-Surgical Nursing A Systems Approach Fundamentals of Medical-Surgical Nursing is a comprehensive yet easy-to-read overview of medical and surgical nursing, designed specifically to support all nursing students learning to care for the adult patient. Highly illustrated and with an easy-to-follow systems-based structure, it provides a thorough foundation in anatomy and physiology, pathophysiology, medical management, and nursing care for the full spectrum of adult health conditions. KEY FEATURES: Extensive coverage of principles of nursing assessment, medication administration, infection prevention and control, and nutritional care Key need-to-know-information and definitions for the anatomy, physiology, and pathology of a range of illnesses and conditions Detailed overviews of nursing care, including patient education, treatment, and complications An online resource centre with a range of extras for both lecturers and students, including case studies, reflective activities, interactive multiple choice questions, and further reading lists Fundamentals of Medical-Surgical Nursing is the ideal textbook to help students succeed on their adult nursing course. with online self-test www.wileyfundamentalseries.com/medicalnursing Interactive multiple-choice questions Reflective questions for downloading Case studies Links to online resources When you purchase the book you also receive access to the Wiley E-Text: Powered by VitalSource. This is an interactive digital version of the book, featuring downloadable text and images, highlighting and notetaking facilities, bookmarking, cross-referencing, in-text searching, and linking to references and abbreviations. Fundamentals of Medical-Surgical Nursing is also available on CourseSmart, offering extra functionality as well as an immediate way to access the book. For more details, see www.coursesmart.co.uk/9780470658239.
Current Challenges In Pharmacovigilance
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Author : World Health Organization
language : en
Publisher:
Release Date : 2001-01-01
Current Challenges In Pharmacovigilance written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Medical categories.
In spite of recent progress in the harmonization of terminology and processes affecting work on the clinical safety of medicines consensus is needed on standards for many difficult aspects of day-to-day pharmacovigilance that continue to pose problems for both the pharmaceutical industry and drug regulators. The CIOMS V Working Group has generated proposals for pragmatic approaches to dealing with such issues as: classification and handling of individual safety case reports from a variety of sources (spontaneous consumer reports solicited reports literature the Internet observational studies and secondary data bases disease and other registries regulatory ADR databases and licensor-licensee interactions); new approaches to case management and regulatory reporting practices (proper clinical evaluation of cases incidental vs other events patient and reporter identifiability seriousness criteria expectedness criteria case follow-up criteria and the role and structure of case narratives); improvements and efficiencies in the format content and reporting of periodic safety update reports (PSURs) (including results of an industry survey on PSUR workloads and practices; proposals for high case volume and long time-period reports simplification of certain PSURs summary bridging reports addendum reports license renewal reports for EU and Japan dealing with old products and other technical details); determination and use of population exposure (denominator) data (sources of data and a guide to analytical approaches for a variety of circumstances).The Group has also taken stock of the current state of expedited and periodic clinical safety reporting requirements around the world with summary data on regulations from more than 60 countries. Recommendations are made for enhancing the harmonization steps already taken as a result of previous CIOMS publications and the ICH process. In addition to dealing with unfinished and unresolved issues from previous CIOMS initiatives the report covers many emerging topics such as those involving new technologies. Its 20 Appendices provide a wealth of detailed explanations and reference information. It is the most comprehensive and recent treatment of difficult pharmacovigilance issues affecting the working practices and systems of drug safety and other pharmaceutical professionals.
Comprehensive Medicinal Chemistry Ii
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Author :
language : en
Publisher:
Release Date : 2007
Comprehensive Medicinal Chemistry Ii written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Drugs categories.
This e-book comprises 8 volumes, with all chapter sections available as PDF or HTML, and includes bibliographical references and index.
Core Entrustable Professional Activities For Entering Residency
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Author :
language : en
Publisher:
Release Date : 2014
Core Entrustable Professional Activities For Entering Residency written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
13 EPAs (Entrustable Professional Activities) that all entering residents should be expected to perform on day 1 of residency without direct supervision regardless of specialty choice. The Core EPAs for entering residency are designed to be a subset of all of the graduation requirements of a medical school. This guide details how the EPAs were mapped.
Links Between Fibrogenesis And Cancer
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Author : Esteban C. Gabazza
language : en
Publisher: MDPI
Release Date : 2019-11-18
Links Between Fibrogenesis And Cancer written by Esteban C. Gabazza and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-18 with Science categories.
Tissue fibrosis may occur for unknown causes or be the consequence of many pathological conditions including chronic inflammatory or infectious diseases, autoimmune disorders, graft rejection, or malignancy. On the other hand, malignant tumors have been identified in fibrotic tissues decades ago, and now accumulating evidence suggests that fibrotic lesions enhance the risk of cancer in several organs such as liver, lungs, and breast. Disruption of an organ parenchymal cells and of its normal structural scaffold during tissue fibrogenesis appears to induce loss of cell polarity, promoting uncontrolled cell proliferation that may eventually lead to cancer development. Many cellular and molecular abnormalities including aberrant expression of microRNAs, genetic and epigenetic alterations, evasion or delayed apoptosis, unregulated intracellular signal pathways, and dysregulation or defective intercellular communications have been proposed to explain this link between fibrogenesis and carcinogenesis. However, the precise mechanisms of this fibrosis-to-cancer transition remain unclear. This book presents a collection of reviews and original articles summarizing recent advances in understanding the molecular mechanisms of cancer development in fibrotic organs.