Flexible Risk Evidence Combination Rules In Breast Cancer Precision Therapy
DOWNLOAD
Download Flexible Risk Evidence Combination Rules In Breast Cancer Precision Therapy PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Flexible Risk Evidence Combination Rules In Breast Cancer Precision Therapy book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Flexible Risk Evidence Combination Rules In Breast Cancer Precision Therapy
DOWNLOAD
Author : Michael Kenn
language : en
Publisher: Infinite Study
Release Date : 2023-01-01
Flexible Risk Evidence Combination Rules In Breast Cancer Precision Therapy written by Michael Kenn and has been published by Infinite Study this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Medical categories.
Evidence theory by Dempster-Shafer for determination of hormone receptor status in breast cancer samples was introduced in our previous paper. One major topic pointed out here is the link between pieces of evidence found from different origins. In this paper the challenge of selecting appropriate ways of fusing evidence, depending on the type and quality of data involved is addressed. A parameterized family of evidence combination rules, covering the full range of potential needs, from emphasizing discrepancies in the measurements to aspiring accordance, is covered. The consequences for real patient samples are shown by modeling different decision strategies.
Advances And Applications Of Dsmt For Information Fusion Collected Works Volume 5
DOWNLOAD
Author : Florentin Smarandache
language : en
Publisher: Infinite Study
Release Date : 2023-12-27
Advances And Applications Of Dsmt For Information Fusion Collected Works Volume 5 written by Florentin Smarandache and has been published by Infinite Study this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-27 with Biography & Autobiography categories.
This fifth volume on Advances and Applications of DSmT for Information Fusion collects theoretical and applied contributions of researchers working in different fields of applications and in mathematics, and is available in open-access. The collected contributions of this volume have either been published or presented after disseminating the fourth volume in 2015 (available at fs.unm.edu/DSmT-book4.pdf or www.onera.fr/sites/default/files/297/2015-DSmT-Book4.pdf) in international conferences, seminars, workshops and journals, or they are new. The contributions of each part of this volume are chronologically ordered. First Part of this book presents some theoretical advances on DSmT, dealing mainly with modified Proportional Conflict Redistribution Rules (PCR) of combination with degree of intersection, coarsening techniques, interval calculus for PCR thanks to set inversion via interval analysis (SIVIA), rough set classifiers, canonical decomposition of dichotomous belief functions, fast PCR fusion, fast inter-criteria analysis with PCR, and improved PCR5 and PCR6 rules preserving the (quasi-)neutrality of (quasi-)vacuous belief assignment in the fusion of sources of evidence with their Matlab codes. Because more applications of DSmT have emerged in the past years since the apparition of the fourth book of DSmT in 2015, the second part of this volume is about selected applications of DSmT mainly in building change detection, object recognition, quality of data association in tracking, perception in robotics, risk assessment for torrent protection and multi-criteria decision-making, multi-modal image fusion, coarsening techniques, recommender system, levee characterization and assessment, human heading perception, trust assessment, robotics, biometrics, failure detection, GPS systems, inter-criteria analysis, group decision, human activity recognition, storm prediction, data association for autonomous vehicles, identification of maritime vessels, fusion of support vector machines (SVM), Silx-Furtif RUST code library for information fusion including PCR rules, and network for ship classification. Finally, the third part presents interesting contributions related to belief functions in general published or presented along the years since 2015. These contributions are related with decision-making under uncertainty, belief approximations, probability transformations, new distances between belief functions, non-classical multi-criteria decision-making problems with belief functions, generalization of Bayes theorem, image processing, data association, entropy and cross-entropy measures, fuzzy evidence numbers, negator of belief mass, human activity recognition, information fusion for breast cancer therapy, imbalanced data classification, and hybrid techniques mixing deep learning with belief functions as well. We want to thank all the contributors of this fifth volume for their research works and their interests in the development of DSmT, and the belief functions. We are grateful as well to other colleagues for encouraging us to edit this fifth volume, and for sharing with us several ideas and for their questions and comments on DSmT through the years. We thank the International Society of Information Fusion (www.isif.org) for diffusing main research works related to information fusion (including DSmT) in the international fusion conferences series over the years. Florentin Smarandache is grateful to The University of New Mexico, U.S.A., that many times partially sponsored him to attend international conferences, workshops and seminars on Information Fusion. Jean Dezert is grateful to the Department of Information Processing and Systems (DTIS) of the French Aerospace Lab (Office National d’E´tudes et de Recherches Ae´rospatiales), Palaiseau, France, for encouraging him to carry on this research and for its financial support. Albena Tchamova is first of all grateful to Dr. Jean Dezert for the opportunity to be involved during more than 20 years to follow and share his smart and beautiful visions and ideas in the development of the powerful Dezert-Smarandache Theory for data fusion. She is also grateful to the Institute of Information and Communication Technologies, Bulgarian Academy of Sciences, for sponsoring her to attend international conferences on Information Fusion.
Personalized Medicine In Oncology
DOWNLOAD
Author : Ari VanderWalde
language : en
Publisher: Mdpi AG
Release Date : 2022-01-25
Personalized Medicine In Oncology written by Ari VanderWalde and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-25 with categories.
Nowhere is the explosion in comprehensive genomic testing more evident than in oncology. Multiple consensus guidelines now recommend molecular testing as the standard of care for most metastatic tumors. To aid in the advancement of this rapidly changing field, we intend this Special Issue of JPM to focus on technical developments in the genomic profiling of cancer, detail promising somatic alterations that either are, or have a high likelihood of being, relevant in the near future, and to address issues related to the pricing and value of these tests. The last few years have seen the cost of molecular testing decrease by orders of magnitude. In 2018, we saw the first "site-agnostic" drug approvals in cancer (for microsatellite unstable cancer (PD-1 inhibitors) and NTRK-fusions (TRK inhibitors)). Research on targetable mutations, determination of genetic "signatures" that can use multiple individual genes/pathways, development of targeted therapy, and insight into the value of new technology remains at the cutting edge of research in this field. We are soliciting papers that present new technologies to assess predictive biomarkers in cancer, original research (pre-clinical or clinical) that demonstrates promise for particular targeted therapies in cancer, and articles that explore the clinical and financial impacts of this paradigmatic shift in cancer diagnostics and treatment.
Personalised Cancer Medicine
DOWNLOAD
Author : Anne Kerr
language : en
Publisher:
Release Date : 2021-02-23
Personalised Cancer Medicine written by Anne Kerr and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-23 with Medical categories.
The Drug Development Paradigm In Oncology
DOWNLOAD
Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2018-02-12
The Drug Development Paradigm In Oncology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-12 with Medical categories.
Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.
Advancing The Science Of Implementation Across The Cancer Continuum
DOWNLOAD
Author : David A. Chambers
language : en
Publisher: Oxford University Press, USA
Release Date : 2018
Advancing The Science Of Implementation Across The Cancer Continuum written by David A. Chambers and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
While many effective interventions have been developed with the potential to significantly reduce morbidity and mortality from cancer, they are of no benefit to the health of populations if they cannot be delivered. In response to this challenge, Advancing the Science of Implementation across the Cancer Continuum provides an overview of research that can improve the delivery of evidence-based interventions in cancer prevention, early detection, treatment, and survivorship. Chapters explore the field of implementation science and its application to practice, a broad synthesis of relevant research and case studies illustrating each cancer-focused topic area, and emerging issues at the intersection of research and practice in cancer. Both comprehensive and accessible, this book is an ideal resource for researchers, clinical and public health practitioners, medical and public health students, and health policymakers.
Improving Cancer Diagnosis And Care
DOWNLOAD
Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-08-15
Improving Cancer Diagnosis And Care written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-15 with Medical categories.
A hallmark of high-quality cancer care is the delivery of the right treatment to the right patient at the right time. Precision oncology therapies, which target specific genetic changes in a patient's cancer, are changing the nature of cancer treatment by allowing clinicians to select therapies that are most likely to benefit individual patients. In current clinical practice, oncologists are increasingly formulating cancer treatment plans using results from complex laboratory and imaging tests that characterize the molecular underpinnings of an individual patient's cancer. These molecular fingerprints can be quite complex and heterogeneous, even within a single patient. To enable these molecular tumor characterizations to effectively and safely inform cancer care, the cancer community is working to develop and validate multiparameter omics tests and imaging tests as well as software and computational methods for interpretation of the resulting datasets. To examine opportunities to improve cancer diagnosis and care in the new precision oncology era, the National Cancer Policy Forum developed a two-workshop series. The first workshop focused on patient access to expertise and technologies in oncologic imaging and pathology and was held in February 2018. The second workshop, conducted in collaboration with the Board on Mathematical Sciences and Analytics, was held in October 2018 to examine the use of multidimensional data derived from patients with cancer, and the computational methods that analyze these data to inform cancer treatment decisions. This publication summarizes the presentations and discussions from the second workshop.
Reducing Environmental Cancer Risk
DOWNLOAD
Author : Suzanne H. Reuben
language : en
Publisher: DIANE Publishing
Release Date : 2010-10
Reducing Environmental Cancer Risk written by Suzanne H. Reuben and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10 with Health & Fitness categories.
Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae
DOWNLOAD
Author : Kulmira Nurgali
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-12
Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae written by Kulmira Nurgali and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-12 with categories.
Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.
Who Guidelines On Physical Activity And Sedentary Behaviour
DOWNLOAD
Author :
language : en
Publisher: World Health Organization
Release Date : 2020-11-20
Who Guidelines On Physical Activity And Sedentary Behaviour written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Medical categories.