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Focal Therapy Of Prostate Cancer


Focal Therapy Of Prostate Cancer
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Technical Aspects Of Focal Therapy In Localized Prostate Cancer


Technical Aspects Of Focal Therapy In Localized Prostate Cancer
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Author : Eric Barret
language : en
Publisher: Springer
Release Date : 2015-01-29

Technical Aspects Of Focal Therapy In Localized Prostate Cancer written by Eric Barret and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-29 with Medical categories.


Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.



Focal Therapy Of Prostate Cancer


Focal Therapy Of Prostate Cancer
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Author : Stefan Thüroff
language : en
Publisher: Springer
Release Date : 2015-03-20

Focal Therapy Of Prostate Cancer written by Stefan Thüroff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-20 with Medical categories.


This book provides a 2015 state of the art update on the hot topic of focal prostate cancer therapy, which offers a means of preserving the prostate and avoiding major side-effects associated with conventional treatment strategies. In so doing, focal therapy meets the desire of many patients, especially those with low-risk disease, to avoid or postpone radical therapies in order to preserve quality of life. A wide range of aspects are covered, including the role of imaging-guided targeted biopsies, the pros and cons of surveillance in comparison with focal therapy, focal hemiablation and focal salvage therapy, multifocal therapies, focal cryotherapy. The potential role of various new diagnostic technologies as well as specific therapeutic devices as "Focal.One" robotic high-intensity focused ultrasound are explained. The authors are all international experts who are long-term proponents of non-invasive treatment of prostate cancer. "Focal Therapy of Prostate Cancer" will be an invaluable source of information for urologists, oncologists, radiation oncologists, and general practitioners, and also for patients wishing to learn more about this new treatment option.



Focal Therapy In Prostate Cancer


Focal Therapy In Prostate Cancer
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Author : Hashim Uddin Ahmed
language : en
Publisher: John Wiley & Sons
Release Date : 2011-12-27

Focal Therapy In Prostate Cancer written by Hashim Uddin Ahmed and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-27 with Medical categories.


This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer.



Imaging And Focal Therapy Of Early Prostate Cancer


Imaging And Focal Therapy Of Early Prostate Cancer
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Author : Thomas J. Polascik
language : en
Publisher: Springer
Release Date : 2017-02-22

Imaging And Focal Therapy Of Early Prostate Cancer written by Thomas J. Polascik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-22 with Medical categories.


This text encompass an up-to-date, comprehensive review of the state-of-the-art for gland preserving therapies. Fully updated and revised, this text evaluates the scientific evidence for the evolving trend to treat intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, is discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on patient selection and outcomes utilizing both advanced imaging techniques and pathologic evaluation. Current and new approaches to image cancer foci within the prostate (multiparametric ultrasonography, multiparametric magnetic resonance image, etc) are presented along with various biopsy techniques, including robotics to map prostate cancer. Patient selection based on imaging and genomic classification, adjuvants to enhance therapy, treatment strategy, outcomes and patient centered concerns is discussed, providing an acceptable balance between cancer control and improved quality of life for patients. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer, Second Edition is designed as a comprehensive resource for urologists, radiation oncologists, medical oncologists, radiologists, uropathologists, molecular biologists, biomedical engineers, other clinicians –- residents, fellows, nurses and allied professionals -- and researchers with an interest in the diagnosis and novel treatment of prostate cancer. It will provide insight into the latest research and clinical applications of image-guided diagnosis and minimally invasive focal, gland-preserving treatment for prostate cancer.



Handbook Of Focal Therapy For Prostate And Renal Cancer


Handbook Of Focal Therapy For Prostate And Renal Cancer
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Author : Truls Bjerklund Johansen
language : en
Publisher: JP Medical Ltd
Release Date : 2016-09-06

Handbook Of Focal Therapy For Prostate And Renal Cancer written by Truls Bjerklund Johansen and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-06 with Medical categories.


Provides a comprehensive, timely review of targeted ablation methods to treat prostate and renal cancers. It describes the most effective techniques in current practice, with discussion of the selection criteria, ablation technologies and their limitations, and advice on the management of common side effects.



Focal Therapy In Prostate Cancer


Focal Therapy In Prostate Cancer
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Author : Richard Ball
language : en
Publisher:
Release Date : 2019

Focal Therapy In Prostate Cancer written by Richard Ball and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.




Focal Therapy In Prostate Cancer


Focal Therapy In Prostate Cancer
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Author : Willemien van den Bos
language : en
Publisher:
Release Date : 2016

Focal Therapy In Prostate Cancer written by Willemien van den Bos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.


"Interesting developments took place in the treatment of prostate cancer including focal therapy for less aggressive organ-confined prostate cancer. Fortunately, curative treatment is often still an option for patients suffering from the lower staged tumors. In carefully selected patients, the prostate cancer may be focally treated followed by careful post-treatment evaluation, and if necessary by focal re-treatment. During the past decades, the age of men at prostate cancer detection has decreased by approximately ten years and men's life expectancy has increased by almost four years. Together with the increased diagnosis of low- and intermediate risk prostate cancer, interest in the minimally invasive focal treatment with its lower side-effect profile has grown. The present thesis deliberates on a minimally invasive approach of treating prostate cancer within the concept of focal therapy. Focal therapy offers a middle ground between active surveillance and radical treatments as surgery or radiation therapy. Focal therapy is a minimally invasive treatment concept whereby active therapy is targeted to the malignant areas of the prostate gland while sparing the benign tissue and vital structures of the prostate aiming at better preservation of the quality of life. Additionally, this thesis provides the initial results of IRE research in prostate cancer that show the safety and feasibility of the procedure, quality of life, post-procedural imaging and histopathological outcomes after an IRE-procedure in the prostate."--Samenvatting auteur.



Focal Therapy For Prostate Cancer Complications And Their Treatment


Focal Therapy For Prostate Cancer Complications And Their Treatment
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Author : Arnas Rakauskas
language : en
Publisher:
Release Date : 2021

Focal Therapy For Prostate Cancer Complications And Their Treatment written by Arnas Rakauskas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.


Focal therapy is a modern alternative to selectively treat a specific part of the prostate harboring clinically significant disease while preserving the rest of the gland. The aim of this therapeutic approach is to retain the oncological benefit of active treatment and to minimize the side-effects of common radical treatments. The oncological effectiveness of focal therapy is yet to be proven in long-term robust trials. In contrast, the toxicity profile is well-established in randomized controlled trials and multiple robust prospective cohort studies. This narrative review summarizes the relevant evidence on complications and their management after focal therapy. When compared to whole gland treatments, focal therapy provides a substantial benefit in terms of adverse events reduction and preservation of genito-urinary function. The most common complications occur in the peri-operative period. Urinary tract infection and acute urinary retention can occur in up to 17% of patients, while dysuria and haematuria are more common. Urinary incontinence following focal therapy is very rare (0-5%), and the vast majority of patients recover in few weeks. Erectile dysfunction can occur after focal therapy in 0-46%: the baseline function and the ablation template are the most important factors predicting post-operative erectile dysfunction. Focal therapy in the salvage setting after external beam radiotherapy has a significantly higher rate of complications. Up to one man in 10 will present a severe complication.



Focal Therapy For Prostate Cancer


Focal Therapy For Prostate Cancer
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Author : Peter T. Scardino
language : en
Publisher:
Release Date : 2008

Focal Therapy For Prostate Cancer written by Peter T. Scardino and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.




The Prostate Cancer Dilemma


The Prostate Cancer Dilemma
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Author : Nelson N. Stone
language : en
Publisher: Springer
Release Date : 2015-10-19

The Prostate Cancer Dilemma written by Nelson N. Stone and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-19 with Medical categories.


This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in early prostate cancer. The book reviews new data about genetic markers, transperineal mapping biopsy and mpMRI, how to apply each of these technologies in patients with elevated PSA, when a prior prostate biopsy performed by the standard TRUS method is negative and in cases where low risk disease is already diagnosed, how to differentiate those men who might harbor more aggressive disease from those who do not. Over 75% of newly diagnosed prostate cancer meets the criteria for low risk disease which has created a dilemma for both patients and clinicians. Active surveillance programs have been initiated and are reviewed. How the new technologies impact surveillance programs is addressed. Clinical stage designation is updated and a new intra-prostatic staging system is discussed. Prostate biopsy techniques utilizing transrectal ultrasound, transperineal mapping, elastography and mpMRI are compared. Finally, utilization of this new technology in the application of focal therapy is reviewed. The Prostate Cancer Dilemma will serve as a very useful resource for physicians and researchers dealing with, and interested in this challenging malignancy. Chapters are written by experts in their fields and include the most up to date scientific and clinical information as well as links to procedural video content.