Focus On Alzheimer S Disease Research
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Focus On Alzheimer S Disease Research
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Author : Eileen M. Welsh
language : en
Publisher: Nova Publishers
Release Date : 2003
Focus On Alzheimer S Disease Research written by Eileen M. Welsh and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Alzheimer's disease categories.
Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. The most common form of dementia among older people is Alzheimer's disease (AD), which involves the parts of the brain that control thought, memory, and language. Age is the most important known risk factor for AD. The number of people with the disease doubles every 5 years beyond age 65. AD is a slow disease, starting with mild memory problems and ending with severe brain damage. The course the disease takes and how fast changes occur vary from person to person. On average, AD patients live from 8 to 10 years after they are diagnosed, though the disease can last for as many as 20 years. Current research is aimed at understanding why AD occurs and who is at greatest risk of developing it, improving the accuracy of diagnosis and the ability to identify those at risk, discovering, developing, and testing new treatments, and discovering treatments for behavioural problems in patients with AD. This new book gathers state-of-the-art research from leading scientists throughout the world which offers important information on understanding the underlying causes and discovering the most effective treatments for Alzheimer's Disease.
Alzheimer S Disease Research
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Author : Christian Behl
language : en
Publisher: Springer Nature
Release Date : 2023-08-14
Alzheimer S Disease Research written by Christian Behl and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-14 with Medical categories.
This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimer’s drugs. As the reader is taken through the major developments in Alzheimer's Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimer's Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimer's pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explain the pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed? In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimer’s research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimer’s Disease research. The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. With its extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimer’s Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimer’s research community is finally ready to shed its ‘amyloid-straitjacket’ that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimer’s Disease research and provide a new and broader perspective on this age-dependent brain disease.
Alzheimer S Disease
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Author : Amy Borenstein
language : en
Publisher: Academic Press
Release Date : 2016-02-16
Alzheimer S Disease written by Amy Borenstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Psychology categories.
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
Frontiers In Clinical Drug Research Alzheimer Disorders
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Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2017-07-31
Frontiers In Clinical Drug Research Alzheimer Disorders written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-31 with Science categories.
Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s disease research.
Global Clinical Trials For Alzheimer S Disease
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Author : Menghis Bairu
language : en
Publisher: Academic Press
Release Date : 2013-08-28
Global Clinical Trials For Alzheimer S Disease written by Menghis Bairu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Medical categories.
Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer’s disease. Written by leading experts with hands-on experience in designing and running global Alzheimer’s disease and other neurodegenerative diseases clinical trials A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer’s disease global clinical trials in emerging markets and developing countries
Frontiers In Clinical Drug Research Alzheimer Disorders
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Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2015-06-04
Frontiers In Clinical Drug Research Alzheimer Disorders written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-04 with Science categories.
Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimers Disease research. The third volume of this series features research on -perfusional modifications in prodromal Alzheimer's disease, -BACE inhibition treatment, -frontotemporal dementia caused by progranulin mutations -evidence-based treatment for psychological symptoms of Alzheimer’s Diseas.
Alzheimer S Disease Decoded The History Present And Future Of Alzheimer S Disease And Dementia Second Edition
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Author : Ronald Sahyouni
language : en
Publisher: World Scientific
Release Date : 2021-12-23
Alzheimer S Disease Decoded The History Present And Future Of Alzheimer S Disease And Dementia Second Edition written by Ronald Sahyouni and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-23 with Medical categories.
This book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a 'global' perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world.Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research.Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease.Dr Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective.This book with appeal to a wide audience, regardless of their scientific or educational background.
Alzheimer S Disease
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Author : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging
language : en
Publisher:
Release Date : 2007
Alzheimer S Disease written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Alzheimer S Disease Drug Development
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Author : Jeffrey Cummings
language : en
Publisher: Cambridge University Press
Release Date : 2022-03-31
Alzheimer S Disease Drug Development written by Jeffrey Cummings and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Business & Economics categories.
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Focus On Cognitive Disorder Research
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Author : William P. Briscoe
language : en
Publisher: Nova Publishers
Release Date : 2007
Focus On Cognitive Disorder Research written by William P. Briscoe and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Attention categories.
Cognitive disorders are defined as those in which a limitation of cognitive functioning is the main feature. They include: amnestic disorders, Huntington's disease, and mental retardation, dementia, delirium, aphasia, and cognitive disorders not otherwise specified. This book brings together leading researchers from throughout the world.