Focus On Cellular Signalling Research
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Focus On Cellular Signalling Research
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Author : Dorothy T. Leeds
language : en
Publisher: Nova Publishers
Release Date : 2006
Focus On Cellular Signalling Research written by Dorothy T. Leeds and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
Cell signalling is the communication inside a cell or with its environment. It plays an important role in cellular growth, survival and apoptosis. For instance, the growth of a cell requires production of certain proteins. The genes that encode these proteins are located in DNA inside the nucleus while the initial signal for cellular growth may come from outside the cell. To induce the expression of these genes, the external signal must pass through specific pathways to reach these genes in DNA. The signalling pathway involves several proteins. If any one of them becomes abnormal or non-functional, the cellular process would be altered, which may cause disease. Therefore, knowing the detailed pathway is very important in understanding the pathogenesis of diseases.
Cellular Signal Transduction In Toxicology And Pharmacology
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Author : Jonathan W. Boyd
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-16
Cellular Signal Transduction In Toxicology And Pharmacology written by Jonathan W. Boyd and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-16 with Science categories.
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Cellular Signal Processing
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Author : Friedrich Marks
language : en
Publisher: Garland Science
Release Date : 2008-11-14
Cellular Signal Processing written by Friedrich Marks and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-14 with Science categories.
Cellular Signal Processing is intended for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. The content is guided by three major principles that are central to signal transduction: the protein network, its energy supply, and its evolution. It includes coverage of all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling. It also highlights the clinical aspects of cell signaling in health and disease.
Structure And Function In Cell Signalling
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Author : John Nelson
language : en
Publisher: John Wiley & Sons
Release Date : 2008-08-06
Structure And Function In Cell Signalling written by John Nelson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-06 with Science categories.
"This book contains extremely detailed and informative content on structure and function of ligands, receptors, and signalling intermediates plus interactions ... the extent of detail and appropriate referencing is impressive." –Microbiology Today, July 2009 "A very well-written book suitable for use as a reference or textbook for an undergraduate subject in cell signalling. For researchers interested in the molecular basis of cell signalling and how aberrant regulation of cell signalling proteins causes diseases, this is an excellent resource of biochemical and structural information." –Australian Biochemist, August 2009 "From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." –Doody's, January 2009 This text is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities – the ‘nuts and bolts’ of cellular information exchange. With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding. An accessible introduction to the complex field of cell signalling Interacts with RasMol software – freely downloadable for viewing structures in 3D Includes exercises and clear instructions in the use of RasMol Well illustrated in full colour throughout Structure and Function in Cell Signalling is an invaluable resource to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book provides a clear, accessible introduction to this rapidly expanding field.
Transduction Mechanisms In Cellular Signaling
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Author : Edward A. Dennis
language : en
Publisher: Academic Press
Release Date : 2011-04-04
Transduction Mechanisms In Cellular Signaling written by Edward A. Dennis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-04 with Science categories.
Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences. Articles written and edited by experts in the field Thematic volume covering material needed for young professionals joining the field of research and graduate students taking survey courses Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease
The Biochemistry Of Cell Signalling
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Author : Ernst J. M. Helmreich
language : en
Publisher: Oxford University Press, USA
Release Date : 2001
The Biochemistry Of Cell Signalling written by Ernst J. M. Helmreich and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Language Arts & Disciplines categories.
A comprehensive study of the principles of cell signalling, concentrating on the structural and mechanistic aspects. The book is divided into four parts describing the machinery of signal transduction, the implementation of the signalling cascades focussing on the effect on gene transcription, the globular cellular regulatory programs, and the loss of regulatory control and its consequences with repsect to the molecular basis of cancer. There are well over 200 figures, many in 3-D representations.
Cell Signalling In Prokaryotes And Lower Metazoa
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Author : I. Fairweather
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Cell Signalling In Prokaryotes And Lower Metazoa written by I. Fairweather and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
Cell signalling lies at the heart of many biological processes and currently is the focus of intense research interest. In multicellular organisms, it is central to how different types of cell communicate with each other and how they detect and respond to extracellular signals. Intercellular communication is vital to single-celled organisms as well, allowing them to respond to environmental cues and signals. To date, much of the understanding of signalling mechanisms has come from research on specific cell types (eg mouse lymphocyte and cardiomyocyte) or on organisms in which communication systems such as nervous and endocrine systems are well established. This volume therefore aims to 'fill the gap' by concentrating on 'simple organisms' where the elements of those signalling systems first evolved. Many of the groups covered contain important pathogens or parasites, and the potential for manipulating signalling pathways for therapeutic intervention will be highlighted.
Cell Signaling In Host Pathogen Interactions The Host Point Of View
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Author : Diana Bahia
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-23
Cell Signaling In Host Pathogen Interactions The Host Point Of View written by Diana Bahia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-23 with categories.
The ability of pathogens, such as parasites, bacteria, fungi and viruses to invade, persist and adapt in both invertebrate and vertebrate hosts is multifactorial and depends on both pathogen and host fitness. Communication between a pathogen and its host relies on a wide and dynamic array of molecular interactions. Through this constant communication most pathogens evolved to be relatively benign, whereas killing of its host by a pathogen represents a failure to adapt. Pathogens are lethal to their host when their interaction has not been long enough for adaptation. Evolution has selected conserved immune receptors that recognize signature patterns of pathogens as non-self elements and initiate host innate responses aimed at eradicating infection. Conversely, pathogens evolved mechanisms to evade immune recognition and subvert cytokine secretion in order to survive, replicate and cause disease. The cell signaling machinery is a critical component of the immune system that relays information from the receptors to the nucleus where transcription of key immune genes is activated. Host cells have developed signal transduction systems to maintain homeostasis with pathogens. Most cellular processes and cell signaling pathways are tightly regulated by protein phosphorylation in which protein kinases are key protagonists. Pathogens have developed multiple mechanisms to subvert important signal transduction pathways such as the mitogen activated protein kinase (MAPK) and the nuclear factor kB (NF-kB) pathways. Pathogens also secrete effectors that manipulate actin cytoskeleton and its regulators, hijack cell cycle machinery and alter vesicular trafficking. This research topic focuses on the cellular signaling mechanisms that are essential for host immunity and their subversion by pathogens.
Signal Transduction
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Author : ljsbrand M. Kramer
language : en
Publisher: Academic Press
Release Date : 2015-10-23
Signal Transduction written by ljsbrand M. Kramer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-23 with Science categories.
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
Cell Signalling
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Author : Barry L. Brown
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1993
Cell Signalling written by Barry L. Brown and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Cell interaction categories.