Transduction Mechanisms In Cellular Signaling
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Transduction Mechanisms In Cellular Signaling
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Author : Edward A. Dennis
language : en
Publisher: Academic Press
Release Date : 2011-04-12
Transduction Mechanisms In Cellular Signaling written by Edward A. Dennis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-12 with Science categories.
"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
Cellular Signal Processing
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Author : Friedrich Marks
language : en
Publisher: Garland Science
Release Date : 2017-05-17
Cellular Signal Processing written by Friedrich Marks and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-17 with Medical categories.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Cellular Signal Transduction In Toxicology And Pharmacology
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Author : Jonathan W. Boyd
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-16
Cellular Signal Transduction In Toxicology And Pharmacology written by Jonathan W. Boyd and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-16 with Science categories.
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Signal Transduction Pathways Mechanisms And Diseases
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Author : Ari Sitaramayya
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-02
Signal Transduction Pathways Mechanisms And Diseases written by Ari Sitaramayya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-02 with Science categories.
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Signal Transduction
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Author : ljsbrand M. Kramer
language : en
Publisher: Academic Press
Release Date : 2015-10-23
Signal Transduction written by ljsbrand M. Kramer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-23 with Science categories.
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
Introduction To Cellular Signal Transduction
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Author : Ari Sitaramayya
language : en
Publisher:
Release Date : 1999
Introduction To Cellular Signal Transduction written by Ari Sitaramayya and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Cellular signal transduction categories.
Signal Transduction
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Author : Bastien D. Gomperts
language : en
Publisher: Gulf Professional Publishing
Release Date : 2003-10-15
Signal Transduction written by Bastien D. Gomperts and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-15 with Medical categories.
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Signal Transduction Mechanisms
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Author : J.A. Barnes
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Signal Transduction Mechanisms written by J.A. Barnes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
This volume contains the proceedings of an International Symposium on `Second Messenger Systems - Molecular, Cellular and Behavioural Aspects', which was held at Tobago on June 16-17, 1994. The interaction of an extracellular agonist (First Messenger) with its plasma membrane receptor leads to the transmission of a signal across the cell membrane and results in the production and/or activation of other signalling molecules (Second Messengers). These Second Messengers control the action of many protein kinases and protein phosphatases and so lead to cellular responses. Although the biochemical basis of the transduction of signals in the main signalling systems in eukaryotic cells is probably largely known, intensified research is ongoing in the following areas: the discovery of specific substrates for many protein kinases, elucidation of the biological significance of the differential tissue expression and heterogeneity of many signalling proteins, and the unravelling of diverse interactions (such as signal potentiation, synergism, antagonism and neuronal co-transmission) between signalling systems. As knowledge from such studies accumulates, it is becoming clear that the `cross talk' interactions between signalling systems are important features of dynamic cell regulation. This volume is designed to summarize some aspects of the current work on various Second Messenger Systems and the integration of signals with respect to plasma membrane receptors. Second Messenger generation and degradation, protein kinase and phosphatase, cell cycle control, and cellular learning and memory.
Introduction To Cellular Signal Transduction
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Author : Ari Sitaramayya
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Introduction To Cellular Signal Transduction written by Ari Sitaramayya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Our understanding of biological communication has grown significantly during the past decade. The advances in knowledge about the chemical nature of signals and their corresponding reception by specialized cells have led to identification, characterization, purification, cloning, and expression of specific receptor molecules. While the earlier literature emphasized com partmentalized treatment of informational molecules and their interaction with receptors, the progress in the recent past has allowed cross-fertilization in the examination of the of actions and mechanisms of steroid and protein hormones and other messengers. Investigators now have an increased ap preciation of the multiple effects of specific hormones and of the diverse responses by receptor proteins to closely related ligands. The task of compil ing this enormous literature into a focused treatise was undertaken with the launching of the series Hormones in Health and Disease. This latest volume, An Introduction to Cellular Signal Transduction, complements the previous monographs in the series and brings to the fore recent developments in the field of biochemical communication. This volume combines discussions on the basic tenets of the signal transduction process and its relevance to health and disease. While various chapters provide exhaustive dissection of specific topics for researchers in the field, the book is also an excellent vehicle for introducing students and new investigators to the subject. The contributors of the chapters are active and accomplished scientists brought together on a common platform by the editor, Dr.
Cell Signaling
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Author : Wendell Lim
language : en
Publisher: Taylor & Francis
Release Date : 2014-06-16
Cell Signaling written by Wendell Lim and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-16 with Science categories.
Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signa
