Folding For The Synapse
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Folding For The Synapse
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Author : Andreas Wyttenbach
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-22
Folding For The Synapse written by Andreas Wyttenbach and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-22 with Science categories.
Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.
Folding For The Synapse
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Author : Andreas Wyttenbach
language : en
Publisher: Springer
Release Date : 2011-07-21
Folding For The Synapse written by Andreas Wyttenbach and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-21 with Medical categories.
Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.
Structural And Functional Organization Of The Synapse
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Author : Johannes W. Hell
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-25
Structural And Functional Organization Of The Synapse written by Johannes W. Hell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-25 with Medical categories.
This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.
The Sticky Synapse
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Author : Michael Hortsch
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-07
The Sticky Synapse written by Michael Hortsch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-07 with Medical categories.
The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.
Histophysiology Of Synapses And Neurosecretion
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Author : Eduardo D.P. De Robertis
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Histophysiology Of Synapses And Neurosecretion written by Eduardo D.P. De Robertis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Histopbysiology of Synapses and Neurosecretion discusses the relationship between subcellular structure and function in synapses. The title discusses how neurosecretion phenomenon takes place in the important areas of central and peripheral nervous system. The first part of text deals with the synapse. Topics such as the concept of synaptic transmission, morphology of synaptic region, and ultrastructure of synaptic region are covered in the first part. Part I also discusses the MORPHO-physiological correlations in certain synapses; and neurochemical studies in isolated nerve endings and synaptic vesicles of the CNS. The second part of the selection covers neorosecretion. Part II tackles the neurohumoral mechanisms and secretion in the hypothalamicneurohypophysial system; secretory processes; and secretion in adrenergic nerves and endings. The book will be of great use to student, researchers, and practitioners of neurology.
Synapses
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Author : W. Maxwell Cowan
language : en
Publisher: JHU Press
Release Date : 2003
Synapses written by W. Maxwell Cowan and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
"For both seasoned neurobiologists and interested newcomers to the field, this book is a worthwhile introduction to the wonders of synapses and the many opportunities for future study that they offer." -- "Science"
The Physiology Of Synapses
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Author : John Carew Eccles
language : en
Publisher: Academic Press
Release Date : 2013-10-22
The Physiology Of Synapses written by John Carew Eccles and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.
Synapse Development
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Author : Tolga Soykan
language : en
Publisher: Springer Nature
Release Date : 2025-04-12
Synapse Development written by Tolga Soykan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-12 with Science categories.
This fully updated volume brings together synapse development methods that span from the macroscopic to the nanoscale in order to foster novel perspectives and encourage interdisciplinary integration. Beginning with a section on in vitro formation and manipulation of synapses, including cutting-edge approaches for neuron differentiation and genomic modification, the book continues by covering methods for dissecting synaptic components at high resolution, utilizing advanced imaging and purification techniques, as well as approaches for studying synaptic networks and activity patterns in their native contexts, featuring methods for labeling, tracing, and quantifying components of developing neural circuits. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Synapse Development: Methods and Protocols, Second Edition serves as valuable resource for researchers seeking to advancing our understanding of how synapses form, transform, and transmit.
Myasthenia Gravis And Myasthenic Disorders
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Author : Andrew G. Engel
language : en
Publisher: Oxford University Press
Release Date : 2012-04-03
Myasthenia Gravis And Myasthenic Disorders written by Andrew G. Engel and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-03 with Medical categories.
Myasthenia Gravis and Myasthenic Disorders, Second Edition is a thoroughly re-written and updated version of the highly successful first edition published in 1999. The current edition begins with an overview of the anatomy and molecular architecture of the neuromuscular junction and the electrophysiologic diagnosis of its disorders. The introductory chapters are followed by a detailed exposition of the pathogenesis, natural history, diagnosis and therapy of the autoimmune myasthenias, the Lambert-Eaton myasthenic syndrome, and the increasingly complex and fascinating diseases collectively referred to as congenital myasthenic syndromes. The acetylcholine receptor is a major target of both autoimmune and inherited myasthenias and a separate chapter reviews its structural and functional properties. The book also describes disorders that often target terminal nerve segment near the neuromuscular junction-- the syndrome of peripheral nerve hyperexcitability and the Guillain-Barré syndrome. Comprehensively written by leaders at the forefront of research, not to mention thoroughly referenced throughout and gorgeously illustrated, this new edition of the classic 1999 text will cement its place as the text on Myasthenia Gravis and related disorders for years to come.
Springer Handbook Of Bio Neuro Informatics
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Author : Nikola Kasabov
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-30
Springer Handbook Of Bio Neuro Informatics written by Nikola Kasabov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-30 with Technology & Engineering categories.
The Springer Handbook of Bio-/Neuro-Informatics is the first published book in one volume that explains together the basics and the state-of-the-art of two major science disciplines in their interaction and mutual relationship, namely: information sciences, bioinformatics and neuroinformatics. Bioinformatics is the area of science which is concerned with the information processes in biology and the development and applications of methods, tools and systems for storing and processing of biological information thus facilitating new knowledge discovery. Neuroinformatics is the area of science which is concerned with the information processes in biology and the development and applications of methods, tools and systems for storing and processing of biological information thus facilitating new knowledge discovery. The text contains 62 chapters organized in 12 parts, 6 of them covering topics from information science and bioinformatics, and 6 cover topics from information science and neuroinformatics. Each chapter consists of three main sections: introduction to the subject area, presentation of methods and advanced and future developments. The Springer Handbook of Bio-/Neuroinformatics can be used as both a textbook and as a reference for postgraduate study and advanced research in these areas. The target audience includes students, scientists, and practitioners from the areas of information, biological and neurosciences. With Forewords by Shun-ichi Amari of the Brain Science Institute, RIKEN, Saitama and Karlheinz Meier of the University of Heidelberg, Kirchhoff-Institute of Physics and Co-Director of the Human Brain Project.