The Sticky Synapse

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The Sticky Synapse

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Author : Michael Hortsch
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-07

The Sticky Synapse written by Michael Hortsch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-07 with Medical categories.

The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.

Development Of The Nervous System

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Author : Dan H. Sanes
language : en
Publisher: Academic Press
Release Date : 2019-06-13

Development Of The Nervous System written by Dan H. Sanes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-13 with Science categories.

Development of the Nervous System, Fourth Edition provides an informative and up-to-date account of our present understanding of the basic principles of neural development as exemplified by key experiments and observations from past and recent times. This book reflects the advances made over the last few years, demonstrating their promise for both therapy and molecular understanding of one of the most complex processes in animal development. This information is critical for neuroscientists, developmental biologists, educators, and students at various stages of their career, providing a clear presentation of the frontiers of this exciting and medically important area of developmental biology. The book includes a basic introduction to the relevant aspects of neural development, covering all the major topics that form the basis of a comprehensive, advanced undergraduate and graduate curriculum, including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity. - Provides broad coverage of concepts and experimental strategies - Includes full color schematics and photographs of critical experiments - Outlines the molecular and genetic basis for most developmental events - Written at a level that is appropriate for advanced undergraduates and beyond - Includes designs of critical experiments that are easy to understand

The Newborn Brain

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Author : Hugo Lagercrantz
language : en
Publisher: Cambridge University Press
Release Date : 2010-01-07

The Newborn Brain written by Hugo Lagercrantz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-07 with Medical categories.

The new edition of this respected work presents a comprehensive review of basic mechanisms of fetal and neonatal brain development.

Supported Lipid Bilayer As A Biomimetic Platform For Neuronal Cell Culture

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Author : Dzmitry Afanasenkau
language : en
Publisher: Forschungszentrum Jülich
Release Date : 2013

Supported Lipid Bilayer As A Biomimetic Platform For Neuronal Cell Culture written by Dzmitry Afanasenkau and has been published by Forschungszentrum Jülich this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.

Cell Adhesion Molecules

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Author : Vladimir Berezin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-18

Cell Adhesion Molecules written by Vladimir Berezin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-18 with Medical categories.

Cell Adhesion Molecules: Implications in Neurological Diseases contains review articles on recent developments in the field of neural cell adhesion molecules (CAMs). The main focus is on the role of cell adhesion molecules in various neurological and neurodegenerative diseases. This perspective has been essentially overlooked in recently published books on neural CAMs. In addition, the contributors cover many newly identified cell adhesion molecules and some that have not received much attention in recent years. This books fills an important gap in the currently available literature. ​

Animal Evolution

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Author : Claus Nielsen
language : en
Publisher: Oxford University Press
Release Date : 2012

Animal Evolution written by Claus Nielsen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Science categories.

Using modern phylogenetic reasoning based on an extensive review of morphology, including ultrastructure, and embryology, each phylum is analysed to ascertain its monophyly and hence its ancestral characters.

The End Of Alzheimer S

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Author : Dale Bredesen
language : en
Publisher: Penguin
Release Date : 2017-08-22

The End Of Alzheimer S written by Dale Bredesen and has been published by Penguin this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-22 with Health & Fitness categories.

The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

Adhesion Of Cells Viruses And Nanoparticles

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Author : Kevin Kendall
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-15

Adhesion Of Cells Viruses And Nanoparticles written by Kevin Kendall and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-15 with Science categories.

"Adhesion of Cells, Viruses and Nanoparticles" describes the adhesion of cells, viruses and nanoparticles starting from the basic principles of adhesion science, familiar to postgraduates, and leading on to recent research results. The underlying theory is that of van der Waals forces acting between cells and substrates, embodied in the molecules lying at the surfaces, together with the geometry and elasticity of the materials involved. The first part describes the fundamental background to adhesion principles, including the phenomenology, the important equations and the modeling ideas. Then the mechanisms of adhesion are explored in the second part, including the elastic deformations of spheres and the importance of the energy of adhesion as measured in various tests. It is demonstrated that adhesion of cells is statistical and depends on Brownian movement and on the complex multiple contacts that can form as cells move around. Then, detailed chapters on cell adhesion, contact of viruses and aggregation of nanoparticles follow in Part 3. Finally, the last chapter looks to the future understanding of cell adhesion and points out some interesting directions of research, development and treatment of diseases related to these phenomena. This book is an ideal resource for researchers on adhesion molecules, receptors, cell and tissue culturing, virus infection, toxicity of nanoparticles and bioreactor fouling. It can also be used to support undergraduate and Masters level teaching courses. "This is a fascinating book and it is an invaluable resource for understanding particle-particle/surface adhesion at micro- and nano- scales. I intend to keep one for my future reference and highly recommend it to my students." (Prof. Zhibing Zhang, School of Chemical Engineering, University of Birmingham, UK)

Basic Neurochemistry

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Author : R. Wayne Albers
language : en
Publisher: Academic Press
Release Date : 2011-11-02

Basic Neurochemistry written by R. Wayne Albers and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-02 with Science categories.

Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475

Billy S Halo

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Author : Ruth McKernan
language : en
Publisher: Random House
Release Date : 2011-07-31

Billy S Halo written by Ruth McKernan and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-31 with Biography & Autobiography categories.

Science is just one way of looking at life. As a neuroscientist working at the forefront of medical research it is Ruth McKernan's way. When her father, Billy, succumbed to a mystery illness and slipped from consciousness into coma, Ruth watched his life ebb away with a mixture of love and terror. She struggled for control by using her scientific knowledge to analyse his medical condition. In this moving account of her father's last year, love, grief and hope are intertwined with a crystal-clear scientific explanation of the way our brains and bodies work. The result is an inspired blend where the contrasting view of scientist and daughter ultimately unite.