Fortschritte Der Krebsforschung
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Recent Results In Cancer Research
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Author : Peter Bannasch
language : en
Publisher:
Release Date : 1968
Recent Results In Cancer Research written by Peter Bannasch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Cancer categories.
Normal And Malignant Cell Growth
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Author : R. J. M. Fry
language : en
Publisher: Elsevier
Release Date : 2014-05-12
Normal And Malignant Cell Growth written by R. J. M. Fry and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Technology & Engineering categories.
Normal and Malignant Cell Growth is a compendium of papers from the "Proceedings of the Third Cancer Training Grant" of the University of Chicago that deals with the processes associated with malignant neoplasia, as well as the cell proliferation kinetics of normal tissues. One paper presents the techniques used in the study on the proliferation kinetics of hemopoietic stem cells, suggesting that the hemopoietic stem cell population is not homogenous but consists of a "primitive pluripotential stem cell." A series of experiments at the Brookhaven National Laboratory investigates the relationship of cell survival, specifically that of stem cells, to the survival of the irradiated test animal. One result of the experiment shows a rapid migration of a number of stem cells from shielded marrow into unshielded marrow at the pressure of a rapid circulating pool. The numbers of stem cells are somewhat dependent on the dose given to the unshielded marrow, and are greater with the greater dose. Another paper also investigates the four methods that are used in the study of cellular kinetics in human tumors. This compendium can prove helpful for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, physiology or oncology.
Ansprache Des Ministerpr Sidenten Fortschritte Auf Dem Gebiet Der Experimentellen Krebsforschung
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Author : Gerhard Domagk
language : de
Publisher: Springer-Verlag
Release Date : 2013-03-09
Ansprache Des Ministerpr Sidenten Fortschritte Auf Dem Gebiet Der Experimentellen Krebsforschung written by Gerhard Domagk and has been published by Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Virusforschung Zoologisches Institut Bonn Fortschritte Der Krebsforschung Wirtschaftliche Und Organisatorische Gesichtspunkte F R Die Verbesserung Unserer Hochschulforschung
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Author : Walter Kikuth
language : de
Publisher: Springer-Verlag
Release Date : 2013-03-13
Virusforschung Zoologisches Institut Bonn Fortschritte Der Krebsforschung Wirtschaftliche Und Organisatorische Gesichtspunkte F R Die Verbesserung Unserer Hochschulforschung written by Walter Kikuth and has been published by Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Science categories.
Special Topics In Carcinogenesis
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Author : E. Grundmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Special Topics In Carcinogenesis written by E. Grundmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
With contributions by numerous experts
Adjuvant Therapies Of Cancer
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Author : Georges Mathe;&AAe;
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Adjuvant Therapies Of Cancer written by Georges Mathe;&AAe; and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Transplantation of syngeneic (donor is a monozygous twin) or allogeneic (donor is an HLA-identical sibling) marrow provides the opportunity for aggressive antileukemic therapy without regard to marrow toxicity. Until 1975, marrow transplantation was carried out only after failure of all other therapy. Consequently, most patients were in advanced relapse. Six of 16 recipients of syngeneic marrow and 13 of 100 recipients of allogeneic marrow are still in remission after 5. 5-10 years [3, 7]. An actuarial survival curve of the first 100 patients grafted in Seattle after conditioning with cyclophos phamide (60 mg/kg on each of 2 successive days) and total body irradiation (1,000 rad) showed three periods of interest: (1) The first 4 months showed a rapid loss of patients associated with advanced illness, graft-versus-host disease, infections (in particular interstitial pneumonias), and recurrent leukemia; (2) from 4 months to 2 years, the curve showed a much slower rate of decline attributable primarily to recurrent leukemia; and (3) from 2-10 years, the curve was almost flat with a negligible loss of patients and no recurrent leukemia. This flat portion of the curve corresponded to 13% of the patients and indicates a strong probability that the majority of these survivors are cured of their disease [8]. Attempts at reducing the incidence of leukemic relapse after transplantation were made by a number of marrow transplant groups by added chemotherapy.
Chemotherapy And Radiotherapy Of Gastrointestinal Tumors
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Author : H.O. Klein
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemotherapy And Radiotherapy Of Gastrointestinal Tumors written by H.O. Klein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Attempts to influence survival of patients with colorectal cancer (CRC) by adjuvant chemotherapy are limited by the variability of survival in different prognostic groups [4] and the paucity of drugs that have shown activity in the advanced disease [10]. Of the few drugs which are active in the advanced disease, only 5-fluorouracil (5-FU) and razoxane «±1,2-bis(3,4-dioxopiperazin-1-yl)propane) are suitable for long-term adjuvant treatment [2, 9]. 5-FU has been widely and intensively studied as adjuvant chemotherapy in CRC [7], but there is no unanimity that it has even the marginal influence on survival that has been claimed [3, 10]. Razoxane has not previously been tested for adjuvant or maintenance treatment in CRC. It has however a number of biological activities which might be thought useful in the treatment of residual or minimal tumours [1] and which might therefore make it useful as an adjuvant. Thus it specifically prevents tumour dissemination and metastases in some tumours and normalizes the neovasculature which the tumours induce [6, 8, 11]. The drug is not cytotoxic in the usual sense, does not affect non-dividing cells, and only blocks cell division during a brief period of the cell cycle in late G and/or early mitosis [12]. It does so non-selectively and most cells capable of 2 division examined so far have been affected by the drug. Even affected cells however are not destroyed immediately, but may increase in size and become multinucleate [5].
The Conduct Of A Cooperative Clinical Trial
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Author : K. E. Stanley
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Conduct Of A Cooperative Clinical Trial written by K. E. Stanley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The purpose of this monograph is to address the basic mecha nisms for organizing trials. Is is meant to serve as a guide to individuals planning to form a cooperative group as well as to cooperative groups who wish to revise and refine their existing procedures. Current literature deals with many components of conducting clinical trials, such as trial design considerations, randomization, and methods of analysis. But there is a lack of accessible knowledge concerning data flow, data processing, and group organization which causes difficulty for many multi institutional cooperative trials. Multi-institutional cooperative studies require greater atten tion to detail than studies within a single institution. For single institution studies, a single protocol document may be suffi cient. In a cooperative group, however, it is necessary to standardize various aspects where little variation may be pre sent in a single institution study. Patients must be entered in a uniform fashion, data collection and evaluation should be standardized, and there must be a mechanism to insure the timely collection of essential data.
Fortschritte Der Krebsforschung
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Author :
language : en
Publisher:
Release Date : 1965
Fortschritte Der Krebsforschung written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965 with Antineoplastic agents categories.
Issues In Cancer Epidemiology And Research 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Issues In Cancer Epidemiology And Research 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Issues in Cancer Epidemiology and Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer Epidemiology and Research. The editors have built Issues in Cancer Epidemiology and Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer Epidemiology and Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Epidemiology and Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.