Recent Results In Cancer Research
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Soft Tissue Sarcomas In Adults
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Author : M. Bamberg
language : en
Publisher: Springer
Release Date : 1994-12-12
Soft Tissue Sarcomas In Adults written by M. Bamberg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-12-12 with Medical categories.
Sarcomas represent a group of rare tumors which arise from the largest tissue compartment of the body, but account only for about 1 % of all malignancies. Among this group of tumors, soft tissue sarcomas in adults are, in addition to osteosarcomas, the most important. In the diagnostic workup of soft tissue sarcomas modern radiological investigation methods such as CT and MRI techniques are being critically evaluated. While it is widely accepted that the conventional, stained microscopic specimen is still the cornerstone for properly planned treatment stra tegies, immunohistochemistry has come to play an indis pensable role in accurate classification. Reviewing the surgical techniques, the treatment of musculo-skeletal malignancies, especially of soft tissue sarcomas, has changed considerably over the past decades. While amputation used to be the surgical treatment of choice limb-saving procedures have now become an im portant therapeutic modality in treating such lesions, particularly in combination with percutaneous or interstitial radiotherapy. Despite adequate local treatment, many patients with soft tissue sarcomas will ultimately develop metastatic disease, usually in the lungs. For this reason, effective ad juvant systemic treatment should be given simultaneously with or soon after treatment of local disease. The results of several randomized trials evaluating adjuvant chemotherapy have been reported in the meanwhile, indicating im proved, disease-free survival with a trend towards improved overall survival. In disseminated disease, drug combi- VI Preface nations or single agents are used as palliative treatment and might help to improve survival in selected subgroups.
Fortschritte Der Krebsforschung
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Author :
language : en
Publisher:
Release Date : 1965
Fortschritte Der Krebsforschung written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965 with Antineoplastic agents categories.
Normal And Malignant Cell Growth
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Author : R. J. M. Fry
language : en
Publisher: Elsevier
Release Date : 2014-05-12
Normal And Malignant Cell Growth written by R. J. M. Fry and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Technology & Engineering categories.
Normal and Malignant Cell Growth is a compendium of papers from the "Proceedings of the Third Cancer Training Grant" of the University of Chicago that deals with the processes associated with malignant neoplasia, as well as the cell proliferation kinetics of normal tissues. One paper presents the techniques used in the study on the proliferation kinetics of hemopoietic stem cells, suggesting that the hemopoietic stem cell population is not homogenous but consists of a "primitive pluripotential stem cell." A series of experiments at the Brookhaven National Laboratory investigates the relationship of cell survival, specifically that of stem cells, to the survival of the irradiated test animal. One result of the experiment shows a rapid migration of a number of stem cells from shielded marrow into unshielded marrow at the pressure of a rapid circulating pool. The numbers of stem cells are somewhat dependent on the dose given to the unshielded marrow, and are greater with the greater dose. Another paper also investigates the four methods that are used in the study of cellular kinetics in human tumors. This compendium can prove helpful for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, physiology or oncology.
Current Problems In The Epidemiology Of Cancer And Lymphomas
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Author : E. Grundmann
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Current Problems In The Epidemiology Of Cancer And Lymphomas written by E. Grundmann and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Recent Results in Cancer Research: Current Problems in the Epidemiology of Cancer and Lymphomas is a collection of papers that tackles the various areas of concerns in cancer research. The text covers the general problems, such as the histopathological definition and classification of tumors. The book also deals with the various types of cancer, such as breast, liver, and prostrate cancers. The selection will be of great use for medical researchers and practitioners, particularly those who are involved in treating and studying cancers.
The Role Of Chromosomes In Cancer Biology
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Author : Peo C. Kollerr
language : en
Publisher: Butterworth-Heinemann
Release Date : 2013-10-22
The Role Of Chromosomes In Cancer Biology written by Peo C. Kollerr and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Health & Fitness categories.
The Role of Chromosomes in Cancer Biology provides a description of the molecular organization and function of chromosomes and the consequences of chromosomal aberrations in human development. The book presents accounts on the structure and function of the chromosome; the cellular features of primary tumors and ascetic fluid; the cytological actions of radiation and drugs and their relevance to therapy. Developmental disorders caused by chromosomal anomalies; chromosome aneuploidy in human malignancies; and viral oncogenesis are discussed as well. The book will prove to be very insightful to those involved in cancer research, oncologists, cytologists, and molecular biologists.
Bone Mineral Metabolism In Cancer
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Author : Janusz Szymendera
language : en
Publisher: Butterworth-Heinemann
Release Date : 2013-10-22
Bone Mineral Metabolism In Cancer written by Janusz Szymendera and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Health & Fitness categories.
Recent Results in Cancer Research: Bone Mineral Metabolism in Cancer presents the clinical approach to bone tissue metabolism, which depends on studying the plasma state, renal handling, kinetics, and balance of calcium and inorganic phosphate. This book discusses the problems of bone mineral metabolism in patients with cancer. Organized into five chapters, this book begins with an overview of the two major phases of bone mineral, namely, amorphous calcium phosphate and crystalline bone apatite. This text then examines the plasma state and renal handling of calcium and inorganic phosphate under controlled metabolic conditions. Other chapters consider the variability of each parameter in the majority of patients without bone secondaries. This book discusses as well the normal remodeling of bone in fertile-age women. The final chapter deals with the plasma state, renal handling, and kinetics of calcium and phosphate in plasmacytoma patients. This book is a valuable resource for oncologists.
Risk And Progression Factors In Carcinogenesis
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Author : H.K. Müller-Hermelink
language : en
Publisher: Springer
Release Date : 1996-09-23
Risk And Progression Factors In Carcinogenesis written by H.K. Müller-Hermelink and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-09-23 with Medical categories.
Cellular transformation and carcinogenesis are considered a multistep process starting with DNA lesions and progressing through loss of cellular growth control and increase invasive and metastatic properties. This book focuses on the demonstration of important steps in carcinogenesis, ranging from chemical interaction of carcinogens with cellular DNA in experimental tumors and cell lines to the analysis of selected human tumors. Special importance is given to the clarification of mechanisms of DNA lesions caused by chemical carcinogens and UV irradiation. Leading scientists describe in review articles the actual state of the art in their specific fields. The reader is informed of trends and scientific approaches to the recognition of pathogenetic mechanisms and factors in malignant tumors.
Small Molecules In Oncology
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Author : Uwe M. Martens
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-14
Small Molecules In Oncology written by Uwe M. Martens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-14 with Medical categories.
Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being targeted directly with rationally designed inhibitors. Apart from monoclonal antibodies, small molecule therapeutics such as oncogenic protein kinase inhibitors are attracting a vast amount of investigational attention. This textbook, written by acknowledged experts, provides a broad overview of the small molecules currently used for the treatment of malignant diseases and discusses interesting novel compounds that are in the process of clinical development to combat cancer.
Recent Advances In Cancer Research And Therapy
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Author : Xin-Yuan Liu
language : en
Publisher: Elsevier
Release Date : 2012-05-18
Recent Advances In Cancer Research And Therapy written by Xin-Yuan Liu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-18 with Medical categories.
Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.
Psycho Oncology
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Author : Ute Goerling
language : en
Publisher: Springer
Release Date : 2018-09-09
Psycho Oncology written by Ute Goerling and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-09 with Medical categories.
This book examines in detail the psychosocial impacts of cancer and its management, explaining the relevance of psycho-oncology during all stages from diagnosis and treatment through to cancer survivorship and rehabilitation and end-of-life care. This new edition has been revised throughout to reflect the latest knowledge and places particular emphasis on patients’ perspectives and what professionals can learn from patients. Readers will find information on a variety of psycho-oncological interventions, and detailed attention is paid to quality of life and patient-reported outcomes (as key benchmarks for successful coping) and to the fear of progression during and after therapy. Entirely new chapters focus on the psychological impact of individualized therapies in oncology, communication skills training, medical risk communication, and current research approaches in psycho-oncology. Written by leading experts in the field, the book will serve as a valuable resource for all health care professionals who work with patients and their relatives in the field of psychosocial cancer care and oncology.