Free Radicals In Synthesis And Biology
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Free Radicals In Synthesis And Biology
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Author : F. Minisci
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Free Radicals In Synthesis And Biology written by F. Minisci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Free-radical reactions have been for long time the domain of the physical chemists and the basic chemical industry (polymerization of vinyl monomers, oxidation by molecular oxygen, chlorination of methane etc.), where the use of simple molecules and the possibility of partial conversions without heavy problems of product separations makes less dramatic the aspects of regio and chemoselectivity. As synonym of unselectivity, free radical reactions were considered of poor use in the synthesis of fine chemicals or sophisticated molecules, where a high selectivity is an essential condition for the success, or in the involvement of biological processes. Within the last 15 years, however, an authentic explosion of synthetic applications of free radical reactions occurred; they have gained a remarkable position among the selective methods of synthesis. At the same time the great importance of free radical reactions in fundamental biological processes and in the metabolism of drugs has been recognized. Thus a specialized meeting on these topics was generally felt appropriate. I had the honour and the onus to organize this workshop because for more than 30 years I have been involved in the research of free radical reactions. Thanks to a generous grant from NATO Scientific Affairs Division and the financial support of CNR and chemical industry (Montedison, Enichem, Zambon) such a meeting among almost 50 specialists and 15 observers of sufficient standard to take advantage of the discussion, became possible at Bardolino (Italy).
Free Radicals In Synthesis And Biology
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Author : F Minisci
language : en
Publisher:
Release Date : 1988-12-31
Free Radicals In Synthesis And Biology written by F Minisci and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-12-31 with categories.
Free Radicals In Biology And Medicine
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Author : Barry Halliwell
language : en
Publisher: Oxford University Press, USA
Release Date : 1989
Free Radicals In Biology And Medicine written by Barry Halliwell and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Biochemistry categories.
"This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), whilst maintaining the clarity of its predecessor. There is expanded coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage), the free radical theory of ageing and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events. Greater emphasis has also been placed on the methods available to measure reactive species and oxidative damage (and their potential pitfalls), as well as the importance of antioxidants in the human diet." "This book is recommended as a comprehensive introduction to the field for students, clinicians and researchers, and an invaluable companion to all those interested in the role of free radicals in the life and medical sciences."--BOOK JACKET.
Free Radicals In Chemistry Biology And Medicine
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Author : Toshikazu Yoshikawa
language : en
Publisher:
Release Date : 2000
Free Radicals In Chemistry Biology And Medicine written by Toshikazu Yoshikawa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Antioxidants categories.
Free Radicals In Chemistry And Biology
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Author : Milan Lazar
language : en
Publisher: CRC Press
Release Date : 1989-03-31
Free Radicals In Chemistry And Biology written by Milan Lazar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-03-31 with Science categories.
Elementary radical reactions are described in terms of fundamental knowledge of organic chemistry and chemical physics in this valuable reference text. The complex radical processes of nonchain and chain mechanisms, such as dimerization, alkylation, polymerization, telomerization, halogenation pyrolysis, oxidation and combustion, are complemented by reactions in chemical lasers and in the cosmos, as well as by reactions in biological objects under normal or pathological metabolism. The text also provides the synthesis of facts from various fields of research and involves mechanisms where free radicals appear either as main or side intermediates in one of the several alternatives of the reaction pathway. Highlights include 38 tables and 39 figures.
Encyclopedia Of Radicals In Chemistry Biology And Materials
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Author : Chryssostomos Chatgilialoglu
language : en
Publisher: Wiley
Release Date : 2012-02-20
Encyclopedia Of Radicals In Chemistry Biology And Materials written by Chryssostomos Chatgilialoglu and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-20 with Science categories.
Highlighting the growing applications of free radicals in key chemical, biological and medical processes Over the last two decades the application of free radicals in organic synthesis, materials science and life science has steadily increased, this Encyclopedia presents methodologies and mechanisms involving free radicals of chemical and biological research, including applications in materials science and medicine. The aim of this Encyclopedia is to offer for the first time a description of free radicals within an interdisciplinary and multidisciplinary context, connecting structural characteristics and chemical properties to their applications in different areas of chemistry and related disciplines. It covers not only basic concepts and chemical synthesis, but also touches on various aspects concerning the role of free radicals in materials and life sciences. The reader will find a balanced contribution of topics related to free radicals covering for example, their role in proteomics, genomics and lipidomics as well as their enormous potential in synthesis and technology. Covers topical areas such as: Alzheimer's disease and antioxidants in food within medicine and life sciences Synthesis and catalysis, combustion and atmospheric chemistry within chemistry Ageing and signalling in biological processes Of interest to anybody working in the field of free radicals in the broadest sense. It will address scientists who want to enter the interdisciplinary field of free radicals. In particular, it is aimed primarily at chemists and life science researchers who want to gain a wider and deeper understanding of free radicals which will allow them to apply free radicals in their own scientific field. The book consists of four themed volumes: Basic Concepts & Methodologies Synthetic Strategies & Applications Chemical Biology Polymers & Materials Online Edition Encyclopedia of Radicals in Chemistry, Biology and Materials is also available online, click here for more details: http://onlinelibrary.wiley.com/book/10.1002/9781119953678
Free Radicals In Biology And Environment
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Author : F. Minisci
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Free Radicals In Biology And Environment written by F. Minisci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Our understanding of the quantitative aspects of free radical chemistry and the involvement of radicals in such areas as biology, medicine, the environment, etc., has developed spectacularly over recent years, yet the various topics are commonly discussed separately, in specific meetings and specialised publications. Free Radicals in Biology and Environment draws together two important areas of free radical chemistry, using as a bridge the fundamental physical chemistry of free radicals (spectroscopic detection of free radicals, evaluation of absolute rate constants, elucidation of mechanisms of free radical reactions and catalysis, photochemical and radiation processes, etc.). The most relevant topics covered are the EPR detection of radicals in biochemical systems and in pollutant formation and degradation, oxidation processes in biology and in the troposphere, radiation and induced damage, and atmospheric pollutants arising from incomplete combustion. Also covered are the chemistry and biochemistry of nitric oxide and peroxynitrite, the chemistry and biochemistry of DNA radicals, the role of radicals in myeloperoxidase, lignineperoxidase, radicals and cardiovascular injury, radiation and the fragmentation of cells and tissues.
Free Radicals In Biology V6
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Author : William Pryor
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Radicals In Biology V6 written by William Pryor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Radicals in Biology, Volume VI covers the significant biological implications of arachidonic acid chemistry in free radical biology. This 11-chapter volume explores the biochemistry of the prostaglandins, leukotrienes, and other products from arachidonic acid. The introductory chapters describe the chemistry of the eicosanoids; the structures of prostaglandin and leukotriene compounds; the role of lipid hydroperoxides in controlling prostaglandin biosynthesis; and the oxidation of xenobiotics during prostaglandin H biosynthesis. The discussion then shifts to the effects of the so-called fatty acid paradoxes on cell proliferation, tumorigenesis, and metastasis, followed by chapters on arachidonic acid cascade process; the causes of lung injury conditions, such as hyperoxia; and the origin of low-level chemiluminescence in cells. This volume further deals with the oxy-radical involvement in parasitic diseases and the mechanisms for activation of aromatic amine carcinogens. The concluding chapters examine the controversial one- and two-electron mechanisms for activation of polynuclear hydrocarbon carcinogens and a hypothesis to rationalize the effects of radicals on the life span of mammals. These chapters propose that aging results from toxic by-products of metabolism, and longevity is determined by the ability of an organism to deal with these products. This book will be of great benefit to biochemists, biologists, and physicists.
Free Radicals In Biology
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Author : William A. Pryor
language : en
Publisher:
Release Date : 1976
Free Radicals In Biology written by William A. Pryor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Biochemistry categories.
Free Radicals in Biology, Volume VI covers the significant biological implications of arachidonic acid chemistry in free radical biology. This 11-chapter volume explores the biochemistry of the prostaglandins, leukotrienes, and other products from arachidonic acid. The introductory chapters describe the chemistry of the eicosanoids; the structures of prostaglandin and leukotriene compounds; the role of lipid hydroperoxides in controlling prostaglandin biosynthesis; and the oxidation of xenobiotics during prostaglandin H biosynthesis. The discussion then shifts to the effects of the so-called f ...
Free Radicals In Biology V1
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Author : William Pryor
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Radicals In Biology V1 written by William Pryor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Radicals in Biology, Volume 1, provides an introduction to some of the basic concepts of free radical biology. The book emerged from the President's Symposium of the American Society for Experimental Pathology held in Atlantic City in April 1970. The book's opening chapter introduces a mechanistic view of free radical reactions using examples from biological systems. This is followed by a discussion of autoxidative damage to lipids in membranes. Some of the special chemistry of lipid oxidation are presented, and a number of novel ideas are suggested. The third chapter deals with the uses of electron-spin resonance in biology. Spin labeling is also discussed, which is one of the most useful methods of probing the chemical and physical environment of molecules in cells. The remaining chapters cover free radicals which occur in photosynthesis and the importance of the enzyme, superoxide dismutase. The study of the occurrence and reactions of this enzyme provides an important and extensive body of data clearly pointing to the significance of free radicals in cellular chemistry.