Function And Control Of The Spx Family Of Proteins Within The Bacterial Stress Response
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Function And Control Of The Spx Family Of Proteins Within The Bacterial Stress Response
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Author : Peter Zuber
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-05
Function And Control Of The Spx Family Of Proteins Within The Bacterial Stress Response written by Peter Zuber and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-05 with Medical categories.
This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.
Advances In Microbial Physiology
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Author : Robert K. Poole
language : en
Publisher: Academic Press
Release Date : 2019-10-24
Advances In Microbial Physiology written by Robert K. Poole and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-24 with Science categories.
Advances in Microbial Physiology, Volume 75, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The book contains updates in the field, with comprehensive chapters covering, Sulfoxides in bacterial systems, RNA degradosomes and control by signals including c-di-GMP, Protein nanowires: biological function and synthetic constructs for 'Green' electronics, Bacterial nitrous oxide respiration: electron transport chains and copper transfer reactions, Multiple degrees of separation in the central pathways of the catabolism of aromatic compounds in Dikarya fungi, and more. - Contains contributions from leading authorities in microbial physiology - Informs and updates on all the latest developments in the field of microbial physiology
Prokaryotic Communications From Macromolecular Interdomain To Intercellular Talks Recognition And Beyond
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Author : Chew Chieng Yeo
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-04
Prokaryotic Communications From Macromolecular Interdomain To Intercellular Talks Recognition And Beyond written by Chew Chieng Yeo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-04 with Science categories.
Molecular Medical Microbiology
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Author : Yi-Wei Tang
language : en
Publisher: Academic Press
Release Date : 2014-09-14
Molecular Medical Microbiology written by Yi-Wei Tang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-14 with Science categories.
The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. - The first comprehensive and accessible reference on molecular medical microbiology - Full color presentation througout - In-depth discussion of individual pathogenic bacteria in a system-oriented approach - Includes a clinical overview for each major bacterial group - Presents the latest information on vaccine development, molecular technology, and diagnostic technology - More than 100 chapters covering all major groups of bacteria - Written by an international panel of authors who are experts in their respective disciplines
Bacterial Transcription Factors And The Cell Cycle
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Author : Morigen Morigen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10
Bacterial Transcription Factors And The Cell Cycle written by Morigen Morigen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Science categories.
Bacterial Transcription Factors And The Cell Cycle 2nd Edition
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Author : Morigen Morigen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-10
Bacterial Transcription Factors And The Cell Cycle 2nd Edition written by Morigen Morigen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-10 with Science categories.
Analogous to the eukaryotic G1, S and M phase of the cell cycle, the bacterial cell cycle can be classified into independent stages. Slowly growing bacterial cells undergo three different stages, B-, C- and D-phase, respectively, while the cell cycle of fast-growing bacteria involves at least two independent cycles: the chromosome replication and the cell division. The oscillation in gene expression regulated by transcription factors, and proteolysis mediated by ClpXP, are closely correlated with progression of the cell cycle. Indeed, it has been shown that DnaA couples DNA replication initiation with the expression of the two oscillating regulators GcrA and CtrA, and the DnaA/GcrA/CtrA regulatory cascade drives the forward progression of the Caulobacter cell cycle. Furthermore, it has been found that: the DnaA oscillation in Eschericha coli and Caulobacter crescentus plays an important role in the cell cycle coordination; RpoS in Coxiella regulates the gene expression involved in the developmental cycle; the SigB and SinR transcription factors control whether cells remain in or leave a biofilm responding to metabolic conditions in Bacillus subtilis; similarly, BolA in most Gram-negative bacteria turns off motility and turns on biofilm development as a transcription factor; CtrA regulates cell division and outer membrane composition of the pathogen Brucella abortus; an essential transcription factor SciP enhances robustness of Caulobacter cell cycle regulation. Interestingly, transcription factors mediated metabolism fluctuations are also related to progression of the cell cycle. It has been shown that: CggR and Cra factors are involved in the flux-signaling metabolite fructose-1,6-bisphosphate; IclR mediates para-hydroxybenzoate catabolism in Streptomyces coelicolor; CceR and AkgR regulate central carbon and energy metabolism in alphaproteobacteria; and these metabolism changes affect cell growth. In line with the argument, AspC-mediated aspartate metabolism coordinates the E. coli cell cycle. However, the molecular mechanisms of maintaining the proper cell cycle progression through coordination of transcription factors mediated gene transcription oscillation, cellular metabolism with the cell cycle are not yet well-established. This Research Topic is intended to cover the spectrum of cell cycle regulatory mechanisms, in particular the coordination of transcription factor mediated gene transcription oscillations, and the cellular metabolisms associated with the cell cycle. We welcome all types of articles including Original Research, Review, and Mini Review. The subject areas of interest include but are not limited to: 1. Cell cycle coordination through gene expression and expression oscillation mediated by transcription factors. 2. Regulation of the cell cycle by proteolysis oscillation. 3. Coordination of the cell cycle with metabolism fluctuation. 4. DNA methylation fluctuation and the cell cycle. 5. Novel transcription factors and gene expression patterns associated with the cell cycle.
Regulatory Potential Of Post Translational Modifications In Bacteria
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Author : Ivan Mijakovic
language : en
Publisher: Frontiers Media SA
Release Date : 2015-07-22
Regulatory Potential Of Post Translational Modifications In Bacteria written by Ivan Mijakovic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-22 with Microbiology categories.
Post-translational modifications (PTMs) are widely employed by all living organisms to control the enzymatic activity, localization or stability of proteins on a much shorter time scale than the transcriptional control. In eukarya, global analyses consistently reveal that proteins are very extensively phosphorylated, acetylated and ubiquitylated. Glycosylation and methylation are also very common, and myriad other PTMs, most with a proven regulatory potential, are being discovered continuously. The emergent picture is that PTM sites on a single protein are not independent; modification of one residue often affects (positively or negatively) modification of other sites on the same protein. The best example of this complex behavior is the histone “bar-code” with very extensive cross-talk between phosphorylation, acetylation and methylation sites. Traditionally it was believed that large networks of PTMs exist only in complex eukaryal cells, which exploit them for coordination and fine-tuning of various cellular functions. PTMs have also been detected in bacteria, but the early examples focused on a few important regulatory events, based mainly on protein phosphorylation. The global importance (and abundance) of PTMs in bacterial physiology was systematically underestimated. In recent years, global studies have reported large datasets of phosphorylated, acetylated and glycosylated proteins in bacteria. Other modifications of bacterial proteins have been recently described: pupylation, methylation, sirtuin acetylation, lipidation, carboxylation and bacillithiolation. As the landscape of PTMs in bacterial cells is rapidly expanding, primarily due to advances of detection methods in mass spectrometry, our research field is adapting to comprehend the potential impact of these modifications on the cellular physiology. The field of protein phosphorylation, especially of the Ser/Thr/Tyr type, has been profoundly transformed. We have become aware that bacterial kinases phosphorylate many protein substrates and thus constitute regulatory nodes with potential for signal integration. They also engage in cross-talk and eukaryal-like mutual activation cascades. The regulatory potential of protein acetylation and glycosylation in bacteria is also rapidly emerging, and the cross-talk between acetylation and phosphorylation has been documented. This topic deals with the complexity of the PTM landscape in bacteria, and focus in particular on the physiological roles that PTMs play and methods to study them. The topic is associated to the 1st International Conference on Post-Translational Modifications in Bacteria (September 9-10, 2014, Göttingen, Germany).
Gram Positive Pathogens
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Author : Vincent A. Fischetti
language : en
Publisher: John Wiley & Sons
Release Date : 2019-10-01
Gram Positive Pathogens written by Vincent A. Fischetti and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-01 with Science categories.
Gram-positive bacteria, lacking an outer membrane and related secretory systems and having a thick peptidoglycan, have developed novel approaches to pathogenesis by acquiring (among others) a unique family of surface proteins, toxins, enzymes, and prophages. For the new edition, the editors have enhanced this fully researched compendium of Gram-positive bacterial pathogens by including new data generated using genomic sequencing as well as the latest knowledge on Gram-positive structure and mechanisms of antibiotic resistance and theories on the mechanisms of Gram-positive bacterial pathogenicity. This edition emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens, with chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically, in an attempt to understand the strategies used by these bacteria to cause human disease. “This textbook comprises a superb collection of scientific knowledge making it a must-read for any graduate student, medical doctor, or investigator studying these gram-positive bacteria and inspiring future imaginations of biological knowledge.” - William R. Jacobs, Jr., PhD, Professor Microbiology & Immunology, Albert Einstein College of Medicine
Insights In Microbial Physiology And Metabolism 2021
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Author : Biswarup Mukhopadhyay
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-16
Insights In Microbial Physiology And Metabolism 2021 written by Biswarup Mukhopadhyay and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-16 with Science categories.
Advances In Microbial Physiology
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-12-07
Advances In Microbial Physiology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-07 with Science categories.
Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 55th volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to "traditional views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series. - 2007 impact factor of 4.9, placing it 13th in the highly competitive category of microbiology - Contributions by leading international scientists - The latest research in microbial physiology