Fundamentals Of Asymmetric Catalysis


Fundamentals Of Asymmetric Catalysis
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Fundamentals Of Asymmetric Catalysis


Fundamentals Of Asymmetric Catalysis
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Author : Patrick J. Walsh
language : en
Publisher: University Science Books
Release Date : 2009-01-02

Fundamentals Of Asymmetric Catalysis written by Patrick J. Walsh and has been published by University Science Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-02 with Science categories.


This work describes the essential aspects of enantioselective catalysis, with chapters organised by concept rather than by reaction type. Each concept is supported by examples to give the reader broad exposure to a wide range of catalysts, reactions and reaction mechanisms.



Comprehensive Asymmetric Catalysis


Comprehensive Asymmetric Catalysis
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Author : Eric N. Jacobsen
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-09-22

Comprehensive Asymmetric Catalysis written by Eric N. Jacobsen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-22 with Science categories.


The first supplement to the three volume reference work "Comprehensive Asymmetric Catalysis" critically reviews new developments to the hottest topics in the field written by recognised experts. Eleven chapters which are already in the major reference work have been supplemented and additionally five new chapters have been included. Thus the state-of-the art in this area is now re-established. Together with the basic three volume book set this supplement is not only the principal reference source for synthetic organic chemists, but also for all scientific researchers who use chiral compounds in their work (for example, in biochemical investigations and molecular medicine) as well as for pharmaceutical chemists and other industrial researchers who prepare chiral compounds.



Asymmetric Catalysis On Industrial Scale


Asymmetric Catalysis On Industrial Scale
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Author : Hans Ulrich Blaser
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-04

Asymmetric Catalysis On Industrial Scale written by Hans Ulrich Blaser and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-04 with Science categories.


This second edition of the pioneering work on this hot topic captures the major trends and latest achievements in the art of asymmetric catalysis on an industrial scale. A number of completely new real-life case studies written by the world leaders in their respective areas provide a compact and qualified insight into this developing field. The resulting ready reference and handbook collates first-hand and valuable information within a context where it can be easily found. The high-quality contributions illustrate the relevant environments and situations, such as time pressure, how the catalytic step fits into the overall synthesis, or competition with other synthetic approaches, as well as the typical problems encountered in the various phases, including finding/developing the catalyst and optimization of the process or choice of equipment. Both successful and unsuccessful approaches to solve these problems are described.



Asymmetric Synthesis


Asymmetric Synthesis
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Author : Mathias Christmann
language : en
Publisher: Wiley-VCH
Release Date : 2007-02-02

Asymmetric Synthesis written by Mathias Christmann and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-02 with Science categories.


A veritable "Who's who" of asymmetric synthesis introduces the reader to the leaders in the field with a four-page concentrate of their area of research along with a short biography. The book is organized into five chapters, each with an introductory preface. Starting from the key concepts of asymmetric synthesis diastereoselective methods, asymmetric catalysis) the Focus then shifts to its application to the synthesis natural products and industrial processes. Graduate students, academic and industrial researchers will find this book a rich source of inspiration for their own work as well as an indispensable tool for the preparation of seminars and exams. A must for everyone in the field.



Catalysis In Asymmetric Synthesis


Catalysis In Asymmetric Synthesis
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Author : Vittorio Caprio
language : en
Publisher: John Wiley & Sons
Release Date : 2009-03-09

Catalysis In Asymmetric Synthesis written by Vittorio Caprio and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-09 with Science categories.


Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods. Topics covered include: Reduction of alkenes, ketones and imines Nucleophilic addition to carbonyl compounds Catalytic carbon-carbon bond forming reactions Catalytic reactions involving metal carbenoids Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.



Comprehensive Asymmetric Catalysis


Comprehensive Asymmetric Catalysis
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Author : Eric N. Jacobsen
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-04-21

Comprehensive Asymmetric Catalysis written by Eric N. Jacobsen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-21 with Science categories.


The second supplement to the three volume reference work Comprehensive Asymmetric Catalysis critically reviews new developments to the hottest topics in the field written by recognised experts. Seven chapters which are already in the major reference work have been supplemented and additionally a new chapter on Aminohydroxylation of Carbon-Carbon Double Bonds has been included. Thus, the state of the art in this area is now re-established. Together with the basic three volume book set and Supplement 1 it is not only the principal reference source for synthetic organic chemists, but also for all scientific researchers who use chiral compounds in their work (for example, in biochemical investigations and molecular medicine) as well as for pharmaceutical chemists and other industrial researchers who prepare chiral compounds.



Comprehensive Asymmetric Catalysis


Comprehensive Asymmetric Catalysis
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Author : Eric N. Jacobsen
language : en
Publisher:
Release Date : 1999

Comprehensive Asymmetric Catalysis written by Eric N. Jacobsen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Asymmetric synthesis categories.


Accompanying CD-ROM contains the full-text search and a state-of-the-art graphic substructure search routine.



Fundamentals Of Asymmetric Synthesis


Fundamentals Of Asymmetric Synthesis
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Author : G. L. David Krupadanam
language : en
Publisher: CRC Press
Release Date : 2014-08-25

Fundamentals Of Asymmetric Synthesis written by G. L. David Krupadanam and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-25 with Medical categories.


Asymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensive—both on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates.



Principles Of Asymmetric Synthesis


Principles Of Asymmetric Synthesis
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Author : R.E. Gawley
language : en
Publisher: Elsevier
Release Date : 1996-11-21

Principles Of Asymmetric Synthesis written by R.E. Gawley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-11-21 with Science categories.


The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. Using examples from the literature of asymmetric synthesis (more than 1300 references), the aim of this book is to present a detailed analysis of the factors that govern stereoselectivity in organic reactions. It is important to note that the references were each individually checked by the authors to verify relevance to the topics under discussion. The study of stereoselectivity has evolved from issues of diastereoselectivity, through auxiliary-based methods for the synthesis of enantiomerically pure compounds (diastereoselectivity followed by separation and auxiliary cleavage), to asymmetric catalysis. In the latter instance, enantiomers (not diastereomers) are the products, and highly selective reactions and modern purification techniques allow preparation - in a single step - of chiral substances in 99% ee for many reaction types. After an explanation of the basic physical-organic principles of stereoselectivity, the authors provide a detailed, annotated glossary of stereochemical terms. A chapter on "Analytical Methods" provides a critical overview of the most common methods for analysis of stereoisomers. The authors then follow the 'tried-and-true' format of grouping the material by reaction type. Thus, there are four chapters on carbon-carbon bond forming reactions (enolate alkylations, organometal additions to carbonyls, aldol and Michael reactions, and cycloadditions and rearrangements), one chapter on reductions and hydroborations (carbon-hydrogen bond forming reactions), and one on oxidations (carbon-oxygen and carbon-nitrogen bond forming reactions). Leading references are provided to natural product synthesis that have been accomplished using a given reaction as a key step. In addition to tables of examples that show high selectivity, a transition state analysis is presented to explain - to the current level of understanding - the stereoselectivity of each reaction. In one case (Cram's rule) the evolution of the current theory is detailed from its first tentative (1952) postulate to the current Felkin-Anh-Heathcock formalism. For other reactions, only the currently accepted rationale is presented. Examination of these rationales also exposes the weaknesses of current theories, in that they cannot always explain the experimental observations. These shortcomings provide a challenge for future mechanistic investigations.



Fundamentals Of Organometallic Catalysis


Fundamentals Of Organometallic Catalysis
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Author : Dirk Steinborn
language : en
Publisher: John Wiley & Sons
Release Date : 2011-11-30

Fundamentals Of Organometallic Catalysis written by Dirk Steinborn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-30 with Technology & Engineering categories.


Vor allem an Studenten fortgeschrittener Semester und Doktoranden gerichtet ist dieses Lehrbuch der Katalyse mit metallorganischen Verbindungen, das auch biologisch relevanten Reaktionen viel Platz einräumt. Hervorragend zum Selbststudium geeignet - mit zahlreichen Übungsaufgaben, nach Schwierigkeitsgraden geordnet und durch Lösungen ergänzt.