Fungal Cell Wall And Immune Response


Fungal Cell Wall And Immune Response
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Fungal Cell Wall And Immune Response


Fungal Cell Wall And Immune Response
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Author : J.P. Latge
language : en
Publisher: Springer
Release Date : 2014-01-13

Fungal Cell Wall And Immune Response written by J.P. Latge and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-13 with Medical categories.


Recent findings on the role of the cell wall of pathogenetic fungi in the pathogenic processes of both vertebrates and invertebrates are presented. The fungal cell wall not only gives shape to the fungus, but it is a dynamic structure allowing fungal growth and survival of fungi in both friendly and adverse environments. It acts as a living sieve controlling the entry of nutrients and the secretion of metabolic products. In terms of fungal pathogenesis, the fungal wall may be responsible for eliciting the defense response of their respective invertebrate or vertebrate hosts or conversely it may provide protection against the host defense system during the pathogenic process.



The Fungal Cell Wall


The Fungal Cell Wall
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Author : Jean-Paul Latgé
language : en
Publisher: Springer Nature
Release Date : 2020-08-12

The Fungal Cell Wall written by Jean-Paul Latgé and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-12 with Science categories.


This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.



Recent Advances In The Study Of The Host Fungus Interaction


Recent Advances In The Study Of The Host Fungus Interaction
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Author : Attila Gacser
language : en
Publisher: Frontiers Media SA
Release Date : 2017-01-13

Recent Advances In The Study Of The Host Fungus Interaction written by Attila Gacser and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-13 with Electronic book categories.


Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.



The Fungal Cell Wall


The Fungal Cell Wall
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Author : Fausto Almeida
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-19

The Fungal Cell Wall written by Fausto Almeida and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-19 with Science categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



The Role Of The Fungal Cell Wall In Host Fungal Interactions


The Role Of The Fungal Cell Wall In Host Fungal Interactions
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Author : Vishukumar Aimanianda
language : en
Publisher: Frontiers Media SA
Release Date : 2020-09-17

The Role Of The Fungal Cell Wall In Host Fungal Interactions written by Vishukumar Aimanianda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-17 with Medical categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference


Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference
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Author : Steven P. Templeton
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-24

Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference written by Steven P. Templeton and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with categories.


Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergence of antifungal-resistant strains. It is therefore of interest to increase our understanding of host-pathogen interactions in order to facilitate the development of new therapies for individuals suffering from fungal infection and disease. These early interactions are shaped by an array of constituent and secreted factors that stimulate or inhibit host immune responses toward protective or detrimental immunity. Likewise, an array of preformed factors and tissue-resident cells provide early protection from fungal infection and provide extracellular signals that result in localized recruitment of inflammatory cells and determine the character of subsequent adaptive antifungal immunity. This Research Topic explores the host and fungal pathways that program innate and adaptive immunity and the immune cells, molecules, and regulatory pathways that comprise protective or detrimental responses to fungal exposure or infection. Over 200 authors contributed reviews, opinions, or original research focusing on antifungal immunity in humans and in experimental models. We believe that the results of these efforts provide a benchmark for further advances and improved antifungal therapies.



Surface Architecture Of Fungal Pathogens


Surface Architecture Of Fungal Pathogens
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Author : Marcio Rodrigues
language : en
Publisher: Frontiers Media SA
Release Date : 2012-05-01

Surface Architecture Of Fungal Pathogens written by Marcio Rodrigues and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-01 with categories.


Surface components in fungal cells include cell wall molecules and, in certain cases, capsular structures. In pathogens, these components are responsible for key events during interaction with the host. These events include recognition of pathogens by the immune system and generation of damage to host cells and tissues. The molecular nature of surface structures in fungi is vast and may include (glyco)proteins, polysaccharides, lipids and pigments. Many of them have been strictly associated with the antifungal immune response, as well as with steps of fungal adhesion and dissemination during interaction with host cells. For many fungal pathogens, surface composition and architecture are determinant for either disease progression or control. The diversity of the composition of the cell surface and its molecular architecture are believed to include targets for the action of new antifungals, as well as immunogens with potential to interfere with fungal diseases in favor of the host.



Fungal Immunology


Fungal Immunology
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Author : Paul L. Fidel
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-09

Fungal Immunology written by Paul L. Fidel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-09 with Medical categories.


A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.



Fungal Infections And Immune Responses


Fungal Infections And Immune Responses
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Author : Juneann W. Murphy
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Fungal Infections And Immune Responses written by Juneann W. Murphy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, including fungi. Because of the devastating acquired immunodeficiency syndrome (AIDS) epidemic, caused by the human immunodeficiency retrovirus, it is now accepted that suppressed immune responses, especially cellular immu nity, are important contributors to increased individual susceptibility to opportunistic infections-including infections caused by fungi which were at one time thought to be very lowly or nonpathogenic. Within the last few years, there has been an almost explosive increase in interest and studies concerning the nature and mechanisms of the immune response to fungal infections. Many immunologists who are not well versed in mycology have begun to study the nature and mechanisms of antifungal immunity using a wide variety of newer as well as more conventional immunologic technologies, both in vivo and in vitro. Up to the 1980s, however, there was little interest among basic immunologists concerning fungal immunity. This situation has changed dramatically in the past half decade, mainly because of AIDS.



Immunology Of Fungal Infections


Immunology Of Fungal Infections
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Author : Gordon D. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-10

Immunology Of Fungal Infections written by Gordon D. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-10 with Medical categories.


This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.