Fungal Infections And Immune Responses


Fungal Infections And Immune Responses
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Fungal Infections And Immune Responses


Fungal Infections And Immune Responses
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Author : Juneann W. Murphy
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Fungal Infections And Immune Responses written by Juneann W. Murphy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, including fungi. Because of the devastating acquired immunodeficiency syndrome (AIDS) epidemic, caused by the human immunodeficiency retrovirus, it is now accepted that suppressed immune responses, especially cellular immu nity, are important contributors to increased individual susceptibility to opportunistic infections-including infections caused by fungi which were at one time thought to be very lowly or nonpathogenic. Within the last few years, there has been an almost explosive increase in interest and studies concerning the nature and mechanisms of the immune response to fungal infections. Many immunologists who are not well versed in mycology have begun to study the nature and mechanisms of antifungal immunity using a wide variety of newer as well as more conventional immunologic technologies, both in vivo and in vitro. Up to the 1980s, however, there was little interest among basic immunologists concerning fungal immunity. This situation has changed dramatically in the past half decade, mainly because of AIDS.



Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference


Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference
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Author : Steven P. Templeton
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-24

Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference written by Steven P. Templeton and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with categories.


Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergence of antifungal-resistant strains. It is therefore of interest to increase our understanding of host-pathogen interactions in order to facilitate the development of new therapies for individuals suffering from fungal infection and disease. These early interactions are shaped by an array of constituent and secreted factors that stimulate or inhibit host immune responses toward protective or detrimental immunity. Likewise, an array of preformed factors and tissue-resident cells provide early protection from fungal infection and provide extracellular signals that result in localized recruitment of inflammatory cells and determine the character of subsequent adaptive antifungal immunity. This Research Topic explores the host and fungal pathways that program innate and adaptive immunity and the immune cells, molecules, and regulatory pathways that comprise protective or detrimental responses to fungal exposure or infection. Over 200 authors contributed reviews, opinions, or original research focusing on antifungal immunity in humans and in experimental models. We believe that the results of these efforts provide a benchmark for further advances and improved antifungal therapies.



Infection And Immunity


Infection And Immunity
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Author : D H Davies
language : en
Publisher: CRC Press
Release Date : 2002-09-11

Infection And Immunity written by D H Davies and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-11 with Medical categories.


This concise text explores the interactions between pathogens and the immune system. Taking a disease-based approach, it explains how micro-organisms adapted to growth in human hosts can evade the immune system and cause disease. The opening chapter overviews the innate and adaptive immune responses to microbes. Subsequent chapters are specific to particular pathogens, beginning with their biology and leading on to illustrate mechanisms of adaptation and ensuing consequences. Each of these chapters ends with a summary, review questions and further reading lists. Summaries, review questions and further reading make this book suitable for self-directed study. Infection and Immunity is ideal for any undergraduates taking a course that explores the interaction between pathogens and the human immune system.



Immunology Of Fungal Infections


Immunology Of Fungal Infections
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Author : Gordon D. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-10

Immunology Of Fungal Infections written by Gordon D. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-10 with Medical categories.


This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.



Fungal Immunology


Fungal Immunology
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Author : Paul L. Fidel
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-09

Fungal Immunology written by Paul L. Fidel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-09 with Medical categories.


A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.



Immunology Of Infection


Immunology Of Infection
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Author : J.G. Sissons
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Immunology Of Infection written by J.G. Sissons and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The immune system has evolved in large part to enable organisms to resist microbial infection. Microorganisms have long been used as experimental tools by immunologists, and the study of the immune response to viruses and bacteria has contributed much to our understanding of basic immunological mechanisms. There are also important practical and clinical reasons for attempting to understand the immunology of infections -- these include the rational design of vaccines, the pathogenesis of infectious diseases, the advent of AIDS, the rise in drug-resistant mycobacterial infections and the recognition of the infectious aetiology of peptic ulcer disease. The contributors to this book are all chosen for their active involvement and expertise in the fields. It bridges the divide between basic immunological research and clinical practice.



Antifungal Immunity


Antifungal Immunity
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Author : Rebecca A. Drummond
language : en
Publisher: Springer Nature
Release Date : 2023-05-05

Antifungal Immunity written by Rebecca A. Drummond and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-05 with Medical categories.


This volume aims to help new investigators to the field by providing them with the protocols needed to set up clinically relevant animal models of fungal infection, as well as methods for in vivo immunology.Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Antifungal Immunity: Methods and Protocols aims to be comprehensive guide for researchers in the field



Immunogenetics Of Fungal Diseases


Immunogenetics Of Fungal Diseases
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Author : Agostinho Carvalho
language : en
Publisher: Springer
Release Date : 2017-04-03

Immunogenetics Of Fungal Diseases written by Agostinho Carvalho and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-03 with Medical categories.


This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies. Different aspects of this emerging field are covered, including epidemiology of fungal diseases, innate and adaptive antifungal immunity, and the role of immunogenetics in defining susceptibility to fungal diseases in primary (CMC, CGD, etc.) immunodeficiencies and hematologic patients. The available information will also be discussed in the scope of new biomarker discovery and development of immunotherapeutic approaches for personalized diagnostics and therapy. The book addresses Professors, researchers and advanced students of Medicine, Immunology, Microbiology and Genetics.



Fungal Cell Wall And Immune Response


Fungal Cell Wall And Immune Response
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Author : J.P. Latge
language : en
Publisher: Springer
Release Date : 2014-01-13

Fungal Cell Wall And Immune Response written by J.P. Latge and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-13 with Medical categories.


Recent findings on the role of the cell wall of pathogenetic fungi in the pathogenic processes of both vertebrates and invertebrates are presented. The fungal cell wall not only gives shape to the fungus, but it is a dynamic structure allowing fungal growth and survival of fungi in both friendly and adverse environments. It acts as a living sieve controlling the entry of nutrients and the secretion of metabolic products. In terms of fungal pathogenesis, the fungal wall may be responsible for eliciting the defense response of their respective invertebrate or vertebrate hosts or conversely it may provide protection against the host defense system during the pathogenic process.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.