Gaba
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Gaba Outside The Cns
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Author : Sandor L. Erdö
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Gaba Outside The Cns written by Sandor L. Erdö and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
during the past few years increasing interest has been focused on the role of gamma-aminobutyric acid (GABA) outside the central nervous systems (CNS).Biochemical, pharmacological, histochemical, physiological approaches have all been employed to investigate the role of GABA in themammalian periphery. The International Symposium on Peripheral GABAergic Mechanism held in Rome, July 1990, was devoted to gather scientists from allover the world in order to summarize and sythesize their most recent results and conceptions on the significance of GABA outside the CNS. Written in a thought-provoking style, this proceedings volume is an overviewof the timely knowledge about GABA in the peripheral nervous system and in non-neuronal tissues. Chapters of the book provide many examples for the diverse functions of this amino acid in the periphery as neurotransmitter, hormone, humoral or even trophic factor from the autonomic ganglia to the endocrine stomach and pancreas, from the tubular epithelium of the kidney to the spermatozoa.
Gaba
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Author :
language : en
Publisher: Elsevier
Release Date : 2006-07-26
Gaba written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-26 with Medical categories.
A great deal of progress has been made in defining GABA (gamma-aminobutyric acid) transmission in the brain. Volume 54 of the Advances in Pharmacology series has also provided new insights into fundamental features of neurotransmission in general, such as the importance of allosterism and coincident signaling in regulating receptor function and overall cellular activity. These studies have led to the design and development of new drugs and potential therapeutic agents. Given the successes achieved over the first 50 years of GABA research, it is certain the 6th decade will yield its share of surprising discoveries and new insights. Published in this volume are articles providing thoughts and perspectives on this topic, some with the benefit of hindsight, others in the context of recent findings, but all with a hint, or prediction, of what the future holds as the secrets of GABA neurotransmission continue to unfold. Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards. *GABA is an amino acid found in mammalian brain *Articles written by leading investigators in the field *Provides new insights into fundamental features of neurotransmission
The Gaba Receptors
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Author : S. J. Enna
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
The Gaba Receptors written by S. J. Enna and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
In this long-awaited 2nd edition of a classic book, leading neuroscientists critically review the latest advances made in our understanding of the fundamental molecular, biochemical, behavioral, and pharmacological properties of GABA receptors. The distinguished contributors clarify the approaches being taken to identify and develop new therapeutic agents for such neurological and psychiatric disorders as epilepsy, memory loss, affective illnesses, and psychosis. They also examine the therapeutic potential that remains in the cloning and expression of the GABA transporter, and in developing additional agents capable of regulating GABA receptor function. The book will play a key role in further expanding the list of drugs that interact with the GABA neurotransmitter system.
Gaba Receptors Transporters And Metabolism
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Author : Chikako Tanaka
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Gaba Receptors Transporters And Metabolism written by Chikako Tanaka and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Highlighting the current developments and future directions in GABA research, the ambitious aim of this topical volume is to cover GABA from the molecular mechanisms of its transmission to new targets for pharmaceutical research. Distinguished scientists at the forefront of GABA research were invited to contribute reviews on glutamate decarboxylase and autoimmunity, molecular structure and functional regulation of GABA transporters, transmitter release and GABA receptor regulation, GABA receptor subtypes and functional regulation, and GABA receptor ligands and their therapeutic application. Describing the latest advances in what has become a rapidly-evolving field, this volume will prove immensely valuable to neuroscientists, pharmacologists, biochemists, and physiologists working in the field of GABA research.
Glutamate And Gaba Receptors And Transporters
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Author : Jan Egebjerg
language : en
Publisher: CRC Press
Release Date : 2001-10-04
Glutamate And Gaba Receptors And Transporters written by Jan Egebjerg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-04 with Science categories.
The ubiquitous presence of glutamate and GABA receptors in the nervous system makes these receptor systems pivotal to our understanding of neurotransmission. Cloning of the molecular components of these receptor systems has provided insights to the selectivity of many drugs and detailed characterisation at the molecular level is emerging. Moreover, continuous development of novel and selective drugs has revealed detailed information on the mechanism of receptor activation and regulation. However, the rapid development of different aspects of glutamate and GABA receptor research makes it increasingly difficult to establish a general view of the field. Studies of the receptors are a multi-disciplinary task employing many specialised techniques. This book conveys recent discoveries in a framework of the basic concepts in the field of glutamate and GABA receptor research. Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology is suitable for postgraduate students studying ligand gated channels but also beneficial for industrial and academic research scientists in both the glutamate and GABA field. Universities offering programs in neuroscience, molecular pharmacology or medicinal chemistry will find this a valuable reference.
Pharmacology Of Gaba And Glycine Neurotransmission
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Author : Hanns Möhler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pharmacology Of Gaba And Glycine Neurotransmission written by Hanns Möhler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Highlighting the current developments and future directions in GABA and glycine research, this volume covers the major inhibitory neurotransmitters from the molecular mechanisms of signal transduction to their role in health and disease. It is of topical importance because these neurotransmitters are essential for brain function and therapy of diseases such as anxiety disorders, insomnias, epilepsy, depression, spasticity, and memory deficits. Distinguished scientists at the forefront of research contributed reviews on the role of these transmitters in governing neuronal networks, their signalling pathways, their receptors, the pharmacology of GABA A- and GABA B- and GABA C-receptors as well as of GABA- and glycine-transporters, and their role in disease. The volume serves as reference for pharmacologists/toxicologists, neuroscientists, neurologists and psychiatrists.
Gaba And Glutamate
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Author : Janko Samardzic
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-03-21
Gaba And Glutamate written by Janko Samardzic and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Medical categories.
This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.
Gaba And Sleep
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Author : Jaime M. Monti
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-28
Gaba And Sleep written by Jaime M. Monti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-28 with Medical categories.
GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. The GABA system is, therefore, of prime clinical relevance for the therapy of insomnia. The focus of this volume is on the neuropsychopharmacology and the clinical impact of the GABA system in regulating sleep and wakefulness. It presents molecular, neuropharmacological, systems-biological and clinical approaches to the understanding of the mechanism of action of GABA and GABAergic drugs. It also explores the role of GABA in the basic drives that affect sleep, and the influences that adapt sleep and wakefulness to external events.
Gaba In The Retina And Central Visual System
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Author :
language : en
Publisher: Elsevier
Release Date : 1992-04-21
Gaba In The Retina And Central Visual System written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-04-21 with Medical categories.
GABA in the Retina and Central Visual System
Diversity And Functions Of Gaba Receptors A Tribute To Hanns M Hler Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-01-12
Diversity And Functions Of Gaba Receptors A Tribute To Hanns M Hler Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-12 with Science categories.
This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development. Contributions from the best authors in the field An essential resource for pharmacologists, immunologists, and biochemists
