Gaba Outside The Cns
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Gaba Outside The Cns
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Author : Sandor L. Erdö
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Gaba Outside The Cns written by Sandor L. Erdö and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
during the past few years increasing interest has been focused on the role of gamma-aminobutyric acid (GABA) outside the central nervous systems (CNS).Biochemical, pharmacological, histochemical, physiological approaches have all been employed to investigate the role of GABA in themammalian periphery. The International Symposium on Peripheral GABAergic Mechanism held in Rome, July 1990, was devoted to gather scientists from allover the world in order to summarize and sythesize their most recent results and conceptions on the significance of GABA outside the CNS. Written in a thought-provoking style, this proceedings volume is an overviewof the timely knowledge about GABA in the peripheral nervous system and in non-neuronal tissues. Chapters of the book provide many examples for the diverse functions of this amino acid in the periphery as neurotransmitter, hormone, humoral or even trophic factor from the autonomic ganglia to the endocrine stomach and pancreas, from the tubular epithelium of the kidney to the spermatozoa.
Gaba Outside The Cns
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Author : Sandor L. Erdö
language : en
Publisher: Springer
Release Date : 1992-02-06
Gaba Outside The Cns written by Sandor L. Erdö and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-02-06 with Medical categories.
during the past few years increasing interest has been focused on the role of gamma-aminobutyric acid (GABA) outside the central nervous systems (CNS).Biochemical, pharmacological, histochemical, physiological approaches have all been employed to investigate the role of GABA in themammalian periphery. The International Symposium on Peripheral GABAergic Mechanism held in Rome, July 1990, was devoted to gather scientists from allover the world in order to summarize and sythesize their most recent results and conceptions on the significance of GABA outside the CNS. Written in a thought-provoking style, this proceedings volume is an overviewof the timely knowledge about GABA in the peripheral nervous system and in non-neuronal tissues. Chapters of the book provide many examples for the diverse functions of this amino acid in the periphery as neurotransmitter, hormone, humoral or even trophic factor from the autonomic ganglia to the endocrine stomach and pancreas, from the tubular epithelium of the kidney to the spermatozoa.
Gaba In The Nervous System
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Author : David L. Martin (M.D.)
language : en
Publisher:
Release Date : 2000
Gaba In The Nervous System written by David L. Martin (M.D.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
GABA in the Nervous System summarizes recent advances in understanding the role of GABA as a neurotransmitter. First discovered as an inhibitory signal in 1950, GABA may also fulfill a decisive role in diseases such as Parkinson's and Alzheimer's, stroke, and other clinical problems. This book provides a comprehensive understanding of GABA at both the molecular and systemic level. Each chapter provides a balanced view of current knowledge while referencing historical discoveries during the last half-century
Gaba In Nervous System Function
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Author : Eugene Roberts
language : en
Publisher:
Release Date : 1976
Gaba In Nervous System Function written by Eugene Roberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medical categories.
Gaba And Glutamate
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Author : Janko Samardzic
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-03-21
Gaba And Glutamate written by Janko Samardzic and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Medical categories.
This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.
Extrasynaptic Gabaa Receptors
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Author : Adam C. Errington
language : en
Publisher: Springer
Release Date : 2014-09-22
Extrasynaptic Gabaa Receptors written by Adam C. Errington and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-22 with Medical categories.
GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.
Magnesium In The Central Nervous System
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Author : Robert Vink
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Magnesium In The Central Nervous System written by Robert Vink and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
The Midbrain Periaqueductal Gray Matter
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Author : Antoine Depaulis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Midbrain Periaqueductal Gray Matter written by Antoine Depaulis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book constitutes the proceedings of a NATO Advanced Research Workshop held at Chateau de Bonas (France) from 10-15 July 1990 on the Midbrain Periaqueductal Gray Matter (PAG). The aim of this meeting was to review and integrate our knowledge about the functional, anatomical and neuro chemical organization of the PAG. The PAG has been the subject of many investi gations during the last decade usually on different topics (e.g., pain modulation, defensive and sexual behavior) and generally there has been little interchange between the different research areas. The main purpose of this meeting was to bring together, for the first time, scientists who have worked on the PAG from different perspectives. This book does not pretend to present an exhaustive review of the data collected during the last 20 years of research on the PAG. The contributors to this book have been selected because their data provide key elements in the search to understand both the organization of the PAG and the role of this structure in the integration of behavior. We believe that this book will provide clues that will assist in unraveling the organization of the PAG in the coming years.
Taurine 3
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Author : Stephen W. Schaffer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Taurine 3 written by Stephen W. Schaffer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
Proceedings of the International Taurine Symposium '97: Neurochemistry, Biochemistry, and Pharmacology held in Tucson, Arizona, July 15-19, 1997
Experimental Neurochemistry
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Author : Abel Lajtha
language : en
Publisher: Springer
Release Date : 1982-12-01
Experimental Neurochemistry written by Abel Lajtha and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-12-01 with Science categories.
The second volume of the Handbook does not parallel any volume of the first edition; it is one more sign, or reflection, of the expansion of the field. By emphasizing the experimental approach, it illustrates the tools that have re cently become available for investigating the nervous system. Also, perhaps even more than other volumes, it illustrates the multidisciplinary nature of the field, requiring multidisciplinary methodology. It is now recognized that the availability of methodology is often the rate-limiting determinant of studies and that improvements or innovations in instrumentation can open up new avenues. A new improved method, although opening up new possibilities and being crucial to making advances, is only a tool whose use will determine its use fulness. If we do not recognize its possibilities, its use will be limited; if we do not recognize its limitations, it will mislead us. It is the possibilities and limitations and the results obtained that are illustrated here.