Gc Ms In Clinical Chemistry
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Gc Ms In Clinical Chemistry
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Author : Petra Gerhards
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-11
Gc Ms In Clinical Chemistry written by Petra Gerhards and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-11 with Science categories.
This book enables the reader to gain a rapid understanding of GC/MS analysis through a basic knowledge of the fundamental principles, linking these with simple and practical applications in the field of industrial medicine and analysis of drugs. Additional information from other specialist fields is also provided with the aim of helping the analyst to understand their relevance to the interpretation of results. The book describes efficient methods of sample preparation and quality assurance and provides information on epidemiology and pharmacology, without which drug screening is impossible. This comprehensive overview is mainly written for the practical analyst in the clinical laboratory but it is equally suited for teaching purposes.
Current Developments In The Clinical Applications Of Hplc Gc And Ms
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Author : A. M. Lawson
language : en
Publisher:
Release Date : 1980
Current Developments In The Clinical Applications Of Hplc Gc And Ms written by A. M. Lawson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.
Selected Approaches To Gas Chromatography Mass Spectrometry In Laboratory Medicine
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Author : Robert S. Melville
language : en
Publisher:
Release Date : 1975
Selected Approaches To Gas Chromatography Mass Spectrometry In Laboratory Medicine written by Robert S. Melville and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Clinical chemistry categories.
Mass Spectrometry For The Clinical Laboratory
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Author : Hari Nair
language : en
Publisher: Academic Press
Release Date : 2016-11-02
Mass Spectrometry For The Clinical Laboratory written by Hari Nair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-02 with Medical categories.
Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab
Chromatographic Methods In Clinical Chemistry And Toxicology
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Author : Roger Bertholf
language : en
Publisher: John Wiley & Sons
Release Date : 2007-01-30
Chromatographic Methods In Clinical Chemistry And Toxicology written by Roger Bertholf and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-30 with Science categories.
This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications. Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers.
Principles And Applications Of Clinical Mass Spectrometry
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Author : Nader Rifai
language : en
Publisher: Elsevier
Release Date : 2018-06-26
Principles And Applications Of Clinical Mass Spectrometry written by Nader Rifai and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-26 with Science categories.
Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field
Clinical Applications Of Mass Spectrometry
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Author :
language : en
Publisher:
Release Date : 2009
Clinical Applications Of Mass Spectrometry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Clinical Applications Of Mass Spectrometry
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Author : Uttam Garg
language : en
Publisher: Humana
Release Date : 2016-08-23
Clinical Applications Of Mass Spectrometry written by Uttam Garg and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.
As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls. Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology.
Clinical Applications Of Mass Spectrometry In Biomolecular Analysis
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Author : Uttam Garg
language : en
Publisher: Springer Nature
Release Date : 2022-09-20
Clinical Applications Of Mass Spectrometry In Biomolecular Analysis written by Uttam Garg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-20 with Science categories.
This updated volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and limited need for specialized reagents. These techniques are essential in laboratory fields including endocrinology, biochemical genetics, drug analysis, proteomics, and pathogen identification. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols, Second Edition is an ideal resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.
Clinical Applications Of Mass Spectrometry In Drug Analysis
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Author : Uttam Garg
language : en
Publisher: Springer Nature
Release Date : 2023-11-30
Clinical Applications Of Mass Spectrometry In Drug Analysis written by Uttam Garg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-30 with Science categories.
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.