Genetic Polymorphism And Disease
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Genetic Polymorphism And Disease
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Author : Syed Sameer Aga
language : en
Publisher: CRC Press
Release Date : 2022-12-06
Genetic Polymorphism And Disease written by Syed Sameer Aga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Science categories.
Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases especially cancers, cardiovascular diseases, immune disorders, neurological pathologies. This book collates the reviews on the roles played by polymorphisms in critical metabolic, signal transduction, cell cycle or DNA repair genes either directly or indirectly in the disease mechanisms. The focus is on various techniques for identifying the various Single Nucleotide Polymorphisms (SNPs). Polymorphism studies document the affect SNPs, and their expressions have upon the functionality of the enzymes, proteins. Key Features Describes the genetic polymorphism and its various types Discusses the role of genetic polymorphisms in modulating the risk of various human diseases Explores various molecular techniques used for detecting GPs Characterizes the role of SNPs in modulating the susceptibility of human diseases Provides a genetic basis for individual variations in response to therapeutics
The Recent Topics In Genetic Polymorphisms
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Author : Mahmut Çalışkan
language : en
Publisher:
Release Date : 2020
The Recent Topics In Genetic Polymorphisms written by Mahmut Çalışkan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Genetic Polymorphisms And Susceptibility To Disease
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Author : Mark Steven Miller
language : en
Publisher: CRC Press
Release Date : 2000-04-27
Genetic Polymorphisms And Susceptibility To Disease written by Mark Steven Miller and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-27 with Science categories.
Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but thorough overview of how allelic gene differences influence disease susceptibility in the human population, and will be a useful reference to researchers across a range of disciplines, for example, on
Discovering Biomolecular Mechanisms With Computational Biology
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Author : Frank Eisenhaber
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-20
Discovering Biomolecular Mechanisms With Computational Biology written by Frank Eisenhaber and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-20 with Science categories.
This anthology presents critical reviews of methods and high-impact applications in computational biology that lead to results that non-bioinformaticians must also know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology explores the methodology of translating sequence strings into biological knowledge and considers exemplary groundbreaking results such as unexpected enzyme discoveries. This book also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation.
Understanding Insulin And Insulin Resistance
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Author : Anil Gupta
language : en
Publisher: Elsevier
Release Date : 2021-11-17
Understanding Insulin And Insulin Resistance written by Anil Gupta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-17 with Medical categories.
Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.
Diagnostic Immunohistochemistry E Book
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Author : David J Dabbs
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-11-29
Diagnostic Immunohistochemistry E Book written by David J Dabbs and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-29 with Medical categories.
User-friendly and concise, the new edition of this popular reference is your #1 guide for the appropriate use of immunohistochemical stains. Dr. David J. Dabbs and leading experts in the field use a consistent, organ system approach to cover all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists. Features a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Contains new material on non-lymphoid malignancies, Hodgkin/non-Hodgkin lymphoma, and an expanded chapter on digital imaging and quantitative immunohistochemistry. Provides new grading schemes for several organs, along with new antibodies to cover more genomic immunohistochemistry applications. Offers more emphasis in the breast section of "eyes on" tissue for molecular/IHC prognostics compared to the current trend of gene-expression profiling of breast cancer. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Genetic Polymorphisms
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Author : Narasimha Reddy Parine
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-09-06
Genetic Polymorphisms written by Narasimha Reddy Parine and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-06 with Medical categories.
The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.
Brenner S Encyclopedia Of Genetics
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Author : Stanley Maloy
language : en
Publisher: Academic Press
Release Date : 2013-03-03
Brenner S Encyclopedia Of Genetics written by Stanley Maloy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-03 with Science categories.
The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike.Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics
Cytokine Gene Polymorphisms In Multifactorial Conditions
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Author : Koen Vandenbroeck
language : en
Publisher: CRC Press
Release Date : 2006-06-21
Cytokine Gene Polymorphisms In Multifactorial Conditions written by Koen Vandenbroeck and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-21 with Medical categories.
The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphism
Genetic Polymorphism And Cancer Susceptibility
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Author : Aga Syed Sameer
language : en
Publisher: Springer Nature
Release Date : 2021-04-22
Genetic Polymorphism And Cancer Susceptibility written by Aga Syed Sameer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-22 with Medical categories.
This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.